SEC24A | ENSG00000113615 | NCBI 10802

Details for: SEC24A

Gene ID: 10802

Symbol: SEC24A

Ensembl ID: ENSG00000113615

Description: SEC24 homolog A, COPII coat complex component

Associated with

Adaptive immune system
(R-HSA-1280218)
Antigen presentation: folding, assembly and peptide loading of class i mhc
(R-HSA-983170)
Asparagine n-linked glycosylation
(R-HSA-446203)
Cargo concentration in the er
(R-HSA-5694530)
Class i mhc mediated antigen processing & presentation
(R-HSA-983169)
Copii-mediated vesicle transport
(R-HSA-204005)
Disease
(R-HSA-1643685)
Er to golgi anterograde transport
(R-HSA-199977)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Membrane trafficking
(R-HSA-199991)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Metabolism of proteins
(R-HSA-392499)
Metabolism of steroids
(R-HSA-8957322)
Mhc class ii antigen presentation
(R-HSA-2132295)
Post-translational protein modification
(R-HSA-597592)
Regulation of cholesterol biosynthesis by srebp (srebf)
(R-HSA-1655829)
Sars-cov-2 activates/modulates innate and adaptive immune responses
(R-HSA-9705671)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Viral infection pathways
(R-HSA-9824446)
Cholesterol homeostasis
(GO:0042632)
Copii-coated vesicle cargo loading
(GO:0090110)
Copii vesicle coat
(GO:0030127)
Cytosol
(GO:0005829)
Endoplasmic reticulum exit site
(GO:0070971)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum to golgi vesicle-mediated transport
(GO:0006888)
Er to golgi transport vesicle membrane
(GO:0012507)
Intracellular protein transport
(GO:0006886)
Positive regulation of protein secretion
(GO:0050714)
Protein binding
(GO:0005515)
Regulation of cholesterol transport
(GO:0032374)
Snare binding
(GO:0000149)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

SEC24-related protein A
B4E205_HUMAN

Genular Protein ID: 2486231775

Symbol: SC24A_HUMAN

Name: SEC24-related protein A

UniProtKB Accession Codes:

O95486 A8MVW3 Q8WUV2 Q96GP7

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10075675

Title: Sec24 proteins and sorting at the endoplasmic reticulum.

PubMed ID: 10075675

DOI: 10.1074/jbc.274.12.7833

PubMed ID: 20427317

Title: Selective export of human GPI-anchored proteins from the endoplasmic reticulum.

PubMed ID: 20427317

DOI: 10.1242/jcs.062950

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31806350

Title: The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.

PubMed ID: 31806350

DOI: 10.1016/j.molcel.2019.10.035

PubMed ID: 34349020

Title: Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization.

PubMed ID: 34349020

DOI: 10.1073/pnas.2100133118

PubMed ID: 17499046

Title: The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.

PubMed ID: 17499046

DOI: 10.1016/j.molcel.2007.03.017

PubMed ID: 18843296

Title: Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.

PubMed ID: 18843296

DOI: 10.1038/emboj.2008.208

PubMed ID: 32690950

Title: STEEP mediates STING ER exit and activation of signaling.

PubMed ID: 32690950

DOI: 10.1038/s41590-020-0730-5

PubMed ID: 32929276

Title:

PubMed ID: 32929276

DOI: 10.1038/s41590-020-0803-5

Sequence Information:

Length: 1093
Mass: 119749
Checksum: E21F3A1333674A6A
Sequence:

MSQPGIPASG GAPASLQAQN GAALASGSPY TNGPVQNALL SSQESVSQGY NFQLPGSYPH 
PIPAKTLNPV SGQSNYGGSQ GSGQTLNRPP VASNPVTPSL HSGPAPRMPL PASQNPATTP 
MPSSSFLPEA NLPPPLNWQY NYPSTASQTN HCPRASSQPT VSGNTSLTTN HQYVSSGYPS 
LQNSFIKSGP SVPPLVNPPL PTTFQPGAPH GPPPAGGPPP VRALTPLTSS YRDVPQPLFN 
SAVNQEGITS NTNNGSMVVH SSYDEIEGGG LLATPQLTNK NPKMSRSVGY SYPSLPPGYQ 
NTTPPGATGV PPSSLNYPSG PQAFTQTPLG ANHLTTSMSG LSLQPEGLRV VNLLQERNML 
PSTPLKPPVP NLHEDIQKLN CNPELFRCTL TSIPQTQALL NKAKLPLGLL LHPFKDLVQL 
PVVTSSTIVR CRSCRTYINP FVSFLDQRRW KCNLCYRVND VPEEFLYNPL TRVYGEPHRR 
PEVQNATIEF MAPSEYMLRP PQPPVYLFVF DVSHNAVETG YLNSVCQSLL DNLDLLPGNT 
RTKIGFITFD STIHFYGLQE SLSQPQMLIV SDIEDVFIPM PENLLVNLNE SKELVQDLLK 
TLPQMFTKTL ETQSALGPAL QAAFKLMSPT GGRMSVFQTQ LPTLGVGALK PREEPNHRSS 
AKDIHMTPST DFYKKLALDC SGQQVAVDLF LLSGQYSDLA SLGCISRYSA GSVYYYPSYH 
HQHNPVQVQK LQKELQRYLT RKIGFEAVMR IRCTKGLSIH TFHGNFFVRS TDLLSLPNVN 
PDAGYAVQMS VEESLTDTQL VSFQSALLYT SSKGERRIRV HTLCLPVVST LNDVFLGADV 
QAISGLLANM AVDRSMTASL SDARDALVNA VIDSLSAYRS SVLSNQQPGL MVPFSLRLFP 
LFVLALLKQK SFQTGTNARL DERIFAMCQV KNQPLVYLML TTHPSLYRVD NLSDEGALNI 
SDRTIPQPPI LQLSVEKLSR DGAFLMDAGS VLMLWVGKNC TQNFLSQVLG VQNYASIPQP 
MTDLPELDTP ESARIIAFIS WLREQRPFFP ILYVIRDESP MKANFLQNMI EDRTESALSY 
YEFLLHIQQQ VNK

Genular Protein ID: 3495087678

Symbol: B4E205_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E205

Database IDs:

Sequence Information:

Length: 857
Mass: 96273
Checksum: 94082DB1C1814008
Sequence:

MYPSPYLIQL STKKVLHQIP ITDLWWSTVV TTRLKEVAYW LTNKNPKMSR SVGYSYPSLP 
PGYQNTTPPG ATGVPPSSLN YPSGPQAFTQ TPLGANHLTT SMSGLSLQPE GLRVVNLLQE 
RNMLPSTPLK PPVPNLHEDI QKLNCNPELF RCTLTSIPQT QALLNKAKLP LGLLLHPFKD 
LVQLPVVTSS TIVRCRSCRT YINPFVSFLD QRRWKCNLCY RVNDVPEEFL YNPLTRVYGE 
PHRRPEVQNA TIEFMAPSEY MLRPPQPPVY LFVFDVSHNA VETGYLNSVC QSLLDNLDLL 
PGNTRTKIGF ITFDSTIHFY GLQESLSQPQ MLIVSDIEDV FIPMPENLLV NLNESKELVQ 
DLLKTLPQMF TKTLETQSAL GPALQAAFKL MSPTGGRMSV FQTQLPTLGV GALKPREEPN 
HRSSAKDIHM TPSTDFYKKL ALDCSGQQVA VDLFLLSGQY SDLASLGCIS RYSAGSVYYY 
PSYHHQHNPV QVQKLQKELQ RYLTRKIGFE AVMRIRCTKG LSIHTFHGNF FVRSTDLLSL 
PNVNPDAGYA VQMSVEESLT DTQLVSFQSA LLYTSSKGER RIRVHTLCLP VVSTLNDVFL 
GADVQAISGL LANMAVDRSM TASLSDARDA LVNAVIDSLS AYRSSVLSNQ QPGLMVPFSL 
RLFPLFVLAL LKQKSFQTGT NARLDERIFA MCQVKNQPLV YLMLTTHPSL YRVDNLSDEG 
ALNISDRTIP QPPILQLSVE KLSRDGAFLM DAGSVLMLWV GKNCTQNFLS QVLGVQNYAS 
IPQPMTDLPE LDTPESARII AFISWLREQR PFFPILYVIR DESPMKANFL QNMIEDRTES 
ALSYYEFLLH IQQQVNK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SEC24A

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sec24 proteins and sorting at the endoplasmic reticulum. PubMed ID: 10075675

Selective export of human GPI-anchored proteins from the endoplasmic reticulum. PubMed ID: 20427317

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1. PubMed ID: 31806350

Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization. PubMed ID: 34349020

The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope. PubMed ID: 17499046

Structural basis of cargo membrane protein discrimination by the human COPII coat machinery. PubMed ID: 18843296

STEEP mediates STING ER exit and activation of signaling. PubMed ID: 32690950