SDCCAG8 | ENSG00000054282 | NCBI 10806

Details for: SDCCAG8

Gene ID: 10806

Symbol: SDCCAG8

Ensembl ID: ENSG00000054282

Description: SHH signaling and ciliogenesis regulator SDCCAG8

Associated with

Anchoring of the basal body to the plasma membrane
(R-HSA-5620912)
Aurka activation by tpx2
(R-HSA-8854518)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Centrosome maturation
(R-HSA-380287)
Cilium assembly
(R-HSA-5617833)
G2/m transition
(R-HSA-69275)
Loss of nlp from mitotic centrosomes
(R-HSA-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-HSA-380284)
Mitotic g2-g2/m phases
(R-HSA-453274)
Mitotic prometaphase
(R-HSA-68877)
M phase
(R-HSA-68886)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Recruitment of mitotic centrosome proteins and complexes
(R-HSA-380270)
Recruitment of numa to mitotic centrosomes
(R-HSA-380320)
Regulation of plk1 activity at g2/m transition
(R-HSA-2565942)
Cell-cell junction
(GO:0005911)
Cell projection organization
(GO:0030030)
Centriolar satellite
(GO:0034451)
Centriole
(GO:0005814)
Centrosome
(GO:0005813)
Centrosome cycle
(GO:0007098)
Ciliary basal body
(GO:0036064)
Cytosol
(GO:0005829)
Establishment of cell polarity
(GO:0030010)
Microtubule organizing center organization
(GO:0031023)
Neuron migration
(GO:0001764)
Photoreceptor cell cilium
(GO:0097733)
Protein binding
(GO:0005515)
Regulation of cilium assembly
(GO:1902017)
Tube formation
(GO:0035148)

Other Information

Proteins

Serologically defined colon cancer antigen 8

Genular Protein ID: 2147329120

Symbol: SDCG8_HUMAN

Name: Serologically defined colon cancer antigen 8

UniProtKB Accession Codes:

Q86SQ7 O60527 Q3ZCR6 Q8N5F2 Q9P0F1

Database IDs:

Citations:

PubMed ID: 12559564

Title: Identification and characterization of the novel centrosome-associated protein CCCAP.

PubMed ID: 12559564

DOI: 10.1016/s0378-1119(02)01141-1

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 9610721

Title: Characterization of human colon cancer antigens recognized by autologous antibodies.

PubMed ID: 9610721

DOI: 10.1002/(sici)1097-0215(19980529)76:5<652::aid-ijc7>3.0.co;2-p

PubMed ID: 20835237

Title: Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy.

PubMed ID: 20835237

DOI: 10.1038/ng.662

PubMed ID: 22940612

Title: FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies.

PubMed ID: 22940612

DOI: 10.1093/hmg/dds368

PubMed ID: 22626039

Title: Mutational analysis of SDCCAG8 in Bardet-Biedl syndrome patients with renal involvement and absent polydactyly.

PubMed ID: 22626039

DOI: 10.3109/13816810.2012.689411

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27224062

Title: SDCCAG8 interacts with RAB effector proteins RABEP2 and ERC1 and is required for Hedgehog Signaling.

PubMed ID: 27224062

DOI: 10.1371/journal.pone.0156081

Sequence Information:

Length: 713
Mass: 82682
Checksum: 04D5304DC3E17640
Sequence:

MAKSPENSTL EEILGQYQRS LREHASRSIH QLTCALKEGD VTIGEDAPNL SFSTSVGNED 
ARTAWPELQQ SHAVNQLKDL LRQQADKESE VSPSRRRKMS PLRSLEHEET NMPTMHDLVH 
TINDQSQYIH HLEAEVKFCK EELSGMKNKI QVVVLENEGL QQQLKSQRQE ETLREQTLLD 
ASGNMHNSWI TTGEDSGVGE TSKRPFSHDN ADFGKAASAG EQLELEKLKL TYEEKCEIEE 
SQLKFLRNDL AEYQRTCEDL KEQLKHKEFL LAANTCNRVG GLCLKCAQHE AVLSQTHTNV 
HMQTIERLVK ERDDLMSALV SVRSSLADTQ QREASAYEQV KQVLQISEEA NFEKTKALIQ 
CDQLRKELER QAERLEKELA SQQEKRAIEK DMMKKEITKE REYMGSKMLI LSQNIAQLEA 
QVEKVTKEKI SAINQLEEIQ SQLASREMDV TKVCGEMRYQ LNKTNMEKDE AEKEHREFRA 
KTNRDLEIKD QEIEKLRIEL DESKQHLEQE QQKAALAREE CLRLTELLGE SEHQLHLTRQ 
EKDSIQQSFS KEAKAQALQA QQREQELTQK IQQMEAQHDK TENEQYLLLT SQNTFLTKLK 
EECCTLAKKL EQISQKTRSE IAQLSQEKRY TYDKLGKLQR RNEELEEQCV QHGRVHETMK 
QRLRQLDKHS QATAQQLVQL LSKQNQLLLE RQSLSEEVDR LRTQLPSMPQ SDC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SDCCAG8

Associated with

Other Information

Identification and characterization of the novel centrosome-associated protein CCCAP. PubMed ID: 12559564

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. PubMed ID: 11042152

Characterization of human colon cancer antigens recognized by autologous antibodies. PubMed ID: 9610721

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. PubMed ID: 20835237

FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies. PubMed ID: 22940612

Mutational analysis of SDCCAG8 in Bardet-Biedl syndrome patients with renal involvement and absent polydactyly. PubMed ID: 22626039

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

SDCCAG8 interacts with RAB effector proteins RABEP2 and ERC1 and is required for Hedgehog Signaling. PubMed ID: 27224062