Details for: CGA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 42.9616
Cell Significance Index: 1147.1400 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 14.6859
Cell Significance Index: 91.2500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 9.5175
Cell Significance Index: 77.6100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 2.7326
Cell Significance Index: 16.5100 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.5015
Cell Significance Index: 36.3700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.3358
Cell Significance Index: 5.2000 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.2683
Cell Significance Index: 3.9100 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.2506
Cell Significance Index: 2.3800 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: 0.2341
Cell Significance Index: 1.1200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1857
Cell Significance Index: 21.6400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0674
Cell Significance Index: 42.1000 - Cell Name: perivascular cell (CL4033054)
Fold Change: 0.0552
Cell Significance Index: 0.2600 - Cell Name: trophoblast giant cell (CL0002488)
Fold Change: 0.0500
Cell Significance Index: 0.3600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0348
Cell Significance Index: 24.0400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0048
Cell Significance Index: 3.5600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0004
Cell Significance Index: -0.0500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0019
Cell Significance Index: -3.6500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0021
Cell Significance Index: -0.4400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0036
Cell Significance Index: -2.0100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0041
Cell Significance Index: -7.4700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0047
Cell Significance Index: -7.2500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0054
Cell Significance Index: -7.3200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0055
Cell Significance Index: -4.1900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0062
Cell Significance Index: -1.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0065
Cell Significance Index: -4.1300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0083
Cell Significance Index: -4.5600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0095
Cell Significance Index: -1.6300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0101
Cell Significance Index: -1.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0104
Cell Significance Index: -3.7200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0130
Cell Significance Index: -0.6600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0133
Cell Significance Index: -3.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0144
Cell Significance Index: -6.5200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0179
Cell Significance Index: -3.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0205
Cell Significance Index: -2.3500 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0214
Cell Significance Index: -0.8800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0243
Cell Significance Index: -3.3400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0267
Cell Significance Index: -3.2800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0288
Cell Significance Index: -4.1800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0348
Cell Significance Index: -0.9700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0373
Cell Significance Index: -1.7400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0389
Cell Significance Index: -4.0500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0428
Cell Significance Index: -5.5300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0431
Cell Significance Index: -4.4000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0434
Cell Significance Index: -0.6400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0512
Cell Significance Index: -3.4400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0528
Cell Significance Index: -6.2300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0544
Cell Significance Index: -1.4000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0547
Cell Significance Index: -4.0800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0553
Cell Significance Index: -4.3800 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0564
Cell Significance Index: -0.9300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0564
Cell Significance Index: -1.1800 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0653
Cell Significance Index: -0.9800 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.0689
Cell Significance Index: -0.6900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0701
Cell Significance Index: -4.3000 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0716
Cell Significance Index: -0.7900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0773
Cell Significance Index: -4.7500 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0790
Cell Significance Index: -1.0300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0794
Cell Significance Index: -3.5100 - Cell Name: suprabasal keratinocyte (CL4033013)
Fold Change: -0.0908
Cell Significance Index: -1.4600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0927
Cell Significance Index: -3.5100 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0929
Cell Significance Index: -4.0400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0934
Cell Significance Index: -5.2400 - Cell Name: chondrocyte (CL0000138)
Fold Change: -0.1006
Cell Significance Index: -1.1600 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: -0.1028
Cell Significance Index: -0.7900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.1039
Cell Significance Index: -1.1300 - Cell Name: myoepithelial cell (CL0000185)
Fold Change: -0.1040
Cell Significance Index: -1.1800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1065
Cell Significance Index: -3.7300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1109
Cell Significance Index: -3.8600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1111
Cell Significance Index: -5.7700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1177
Cell Significance Index: -1.6900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1210
Cell Significance Index: -3.9600 - Cell Name: osteoblast (CL0000062)
Fold Change: -0.1216
Cell Significance Index: -1.1800 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.1229
Cell Significance Index: -0.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1247
Cell Significance Index: -3.9700 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1267
Cell Significance Index: -3.1600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1302
Cell Significance Index: -3.4900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1367
Cell Significance Index: -3.9000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1382
Cell Significance Index: -4.0700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1429
Cell Significance Index: -3.7600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1438
Cell Significance Index: -5.2800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1522
Cell Significance Index: -7.1600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1554
Cell Significance Index: -2.1200 - Cell Name: thymocyte (CL0000893)
Fold Change: -0.1622
Cell Significance Index: -2.0500 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1629
Cell Significance Index: -4.1500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1646
Cell Significance Index: -4.8400 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1672
Cell Significance Index: -2.3200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1676
Cell Significance Index: -4.1800 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1677
Cell Significance Index: -2.8200 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.1762
Cell Significance Index: -2.2800 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.1830
Cell Significance Index: -1.9300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1874
Cell Significance Index: -5.4000 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1907
Cell Significance Index: -2.7100 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1922
Cell Significance Index: -4.8000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1939
Cell Significance Index: -4.1900 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1961
Cell Significance Index: -3.9900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1982
Cell Significance Index: -3.9800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2007
Cell Significance Index: -4.2600 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.2016
Cell Significance Index: -2.7200 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2022
Cell Significance Index: -4.2200 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.2036
Cell Significance Index: -4.0600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3294534032
Symbol: GLHA_HUMAN
Name: Glycoprotein hormones alpha chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 481597
Title: Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotropin.
PubMed ID: 481597
DOI: 10.1038/281351a0
PubMed ID: 8196184
Title: Structure and regulation of human thyroid-stimulating hormone (TSH) gene.
PubMed ID: 8196184
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6286817
Title: The gene encoding the common alpha subunit of the four human glycoprotein hormones.
PubMed ID: 6286817
PubMed ID: 7462224
Title: The amino acid sequences of the prepeptides contained in the alpha and beta subunits of human choriogonadotropin.
PubMed ID: 7462224
PubMed ID: 890569
Title: Human pituitary thyrotropin. The primary structure of the alpha and beta subunits.
PubMed ID: 890569
DOI: 10.1139/o77-108
PubMed ID: 5065401
Title: Human pituitary interstitial cell stimulating hormone: primary structure of the alpha-subunit.
PubMed ID: 5065401
PubMed ID: 1158880
Title: Primary amino acid sequence of follicle-stimulating hormone from human pituitary glands. I. alpha subunit.
PubMed ID: 1158880
PubMed ID: 4835135
Title: Human follicle stimulating hormone (hFSH): first proposal for the amino acid sequence of the alpha-subunit (hFSHa) and first demonstration of its identity with the alpha-subunit of human luteinizing hormone (hLHa).
PubMed ID: 4835135
PubMed ID: 1150658
Title: The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.
PubMed ID: 1150658
PubMed ID: 4745444
Title: Human chorionic gonadotropin. Linear amino acid sequence of the alpha subunit.
PubMed ID: 4745444
PubMed ID: 6774759
Title: Studies on the disulfide bonds in human pituitary follicle-stimulating hormone.
PubMed ID: 6774759
PubMed ID: 7410374
Title: Assignment of disulfide bonds in the alpha subunit of human chorionic gonadotropin.
PubMed ID: 7410374
PubMed ID: 1991473
Title: NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin.
PubMed ID: 1991473
PubMed ID: 2494176
Title: Expression of biologically active human follitropin in Chinese hamster ovary cells.
PubMed ID: 2494176
PubMed ID: 8202136
PubMed ID: 8898911
Title: NMR studies of the free alpha subunit of human chorionic gonadotropin. Structural influences of N-glycosylation and the beta subunit on the conformation of the alpha subunit.
PubMed ID: 8898911
PubMed ID: 15662415
Title: Structure of human follicle-stimulating hormone in complex with its receptor.
PubMed ID: 15662415
DOI: 10.1038/nature03206
PubMed ID: 24692546
Title: Evidence for follicle-stimulating hormone receptor as a functional trimer.
PubMed ID: 24692546
Sequence Information:
- Length: 116
- Mass: 13075
- Checksum: F0623CD8CC90CFCD
- Sequence:
MDYYRKYAAI FLVTLSVFLH VLHSAPDVQD CPECTLQENP FFSQPGAPIL QCMGCCFSRA YPTPLRSKKT MLVQKNVTSE STCCVAKSYN RVTVMGGFKV ENHTACHCST CYYHKS
Genular Protein ID: 2593547026
Symbol: A0A087WYZ4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 147
- Mass: 16306
- Checksum: AEE3CD031FEF95AE
- Sequence:
MDYYRKYAAI FLVTLSVFLH VLHSAPDVQE TGFHHVAQAA LKLLSSSNPP TKASQSARIT DCPECTLQEN PFFSQPGAPI LQCMGCCFSR AYPTPLRSKK TMLVQKNVTS ESTCCVAKSY NRVTVMGGFK VENHTACHCS TCYYHKS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.