Details for: NOXA1

Gene ID: 10811

Symbol: NOXA1

Ensembl ID: ENSG00000188747

Description: NADPH oxidase activator 1

Associated with

Other Information

Genular Protein ID: 1249225188

Symbol: NOXA1_HUMAN

Name: NADPH oxidase activator 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12657628

Title: Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells.

PubMed ID: 12657628

DOI: 10.1074/jbc.m301289200

PubMed ID: 12716910

Title: Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.

PubMed ID: 12716910

DOI: 10.1074/jbc.m212856200

PubMed ID: 17602954

Title: NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain.

PubMed ID: 17602954

DOI: 10.1016/j.freeradbiomed.2007.04.022

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9610721

Title: Characterization of human colon cancer antigens recognized by autologous antibodies.

PubMed ID: 9610721

DOI: 10.1002/(sici)1097-0215(19980529)76:5<652::aid-ijc7>3.0.co;2-p

PubMed ID: 14617635

Title: NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain.

PubMed ID: 14617635

DOI: 10.1074/jbc.m305968200

PubMed ID: 15181005

Title: Nox3 regulation by NOXO1, p47phox, and p67phox.

PubMed ID: 15181005

DOI: 10.1074/jbc.m400660200

PubMed ID: 14978110

Title: Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells.

PubMed ID: 14978110

DOI: 10.4049/jimmunol.172.5.3051

PubMed ID: 15824103

Title: The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.

PubMed ID: 15824103

DOI: 10.1074/jbc.m414548200

PubMed ID: 16329988

Title: Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1.

PubMed ID: 16329988

DOI: 10.1016/j.bbrc.2005.11.108

PubMed ID: 16636067

Title: Nox1-dependent reactive oxygen generation is regulated by Rac1.

PubMed ID: 16636067

DOI: 10.1074/jbc.m512751200

PubMed ID: 16762923

Title: Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.

PubMed ID: 16762923

DOI: 10.1074/jbc.m513665200

PubMed ID: 16507994

Title: Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases.

PubMed ID: 16507994

DOI: 10.1128/mcb.26.6.2160-2174.2006

PubMed ID: 17126813

Title: Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1).

PubMed ID: 17126813

DOI: 10.1016/j.bbrc.2006.11.060

PubMed ID: 17913709

Title: Regulation of Nox1 activity via PKA-mediated phosphorylation of NoxA1 and 14-3-3 binding.

PubMed ID: 17913709

DOI: 10.1074/jbc.m704754200

PubMed ID: 19755710

Title: Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.

PubMed ID: 19755710

DOI: 10.1126/scisignal.2000370

PubMed ID: 20609497

Title: Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation.

PubMed ID: 20609497

DOI: 10.1016/j.ejcb.2010.05.007

Sequence Information:

  • Length: 476
  • Mass: 50933
  • Checksum: 64DFBF64C59722AD
  • Sequence:
  • MASLGDLVRA WHLGAQAVDR GDWARALHLF SGVPAPPARL CFNAGCVHLL AGDPEAALRA 
    FDQAVTKDTC MAVGFFQRGV ANFQLARFQE ALSDFWLALE QLRGHAAIDY TQLGLRFKLQ 
    AWEVLHNVAS AQCQLGLWTE AASSLREAMS KWPEGSLNGL DSALDQVQRR GSLPPRQVPR 
    GEVFRPHRWH LKHLEPVDFL GKAKVVASAI PDDQGWGVRP QQPQGPGANH DARSLIMDSP 
    RAGTHQGPLD AETEVGADRC TSTAYQEQRP QVEQVGKQAP LSPGLPAMGG PGPGPCEDPA 
    GAGGAGAGGS EPLVTVTVQC AFTVALRARR GADLSSLRAL LGQALPHQAQ LGQLSYLAPG 
    EDGHWVPIPE EESLQRAWQD AAACPRGLQL QCRGAGGRPV LYQVVAQHSY SAQGPEDLGF 
    RQGDTVDVLC EVDQAWLEGH CDGRIGIFPK CFVVPAGPRM SGAPGRLPRS QQGDQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.