FRS3 | ENSG00000137218 | NCBI 10817

Details for: FRS3

Gene ID: 10817

Symbol: FRS3

Ensembl ID: ENSG00000137218

Description: fibroblast growth factor receptor substrate 3

Associated with

Activated ntrk2 signals through frs2 and frs3
(R-HSA-9028731)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Downstream signaling of activated fgfr1
(R-HSA-5654687)
Downstream signaling of activated fgfr2
(R-HSA-5654696)
Downstream signaling of activated fgfr3
(R-HSA-5654708)
Downstream signaling of activated fgfr4
(R-HSA-5654716)
Frs-mediated fgfr1 signaling
(R-HSA-5654693)
Frs-mediated fgfr2 signaling
(R-HSA-5654700)
Frs-mediated fgfr3 signaling
(R-HSA-5654706)
Frs-mediated fgfr4 signaling
(R-HSA-5654712)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Raf/map kinase cascade
(R-HSA-5673001)
Rho gtpase cycle
(R-HSA-9012999)
Rnd1 gtpase cycle
(R-HSA-9696273)
Rnd2 gtpase cycle
(R-HSA-9696270)
Signaling by alk fusions and activated point mutants
(R-HSA-9725370)
Signaling by alk in cancer
(R-HSA-9700206)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr1
(R-HSA-5654736)
Signaling by fgfr2
(R-HSA-5654738)
Signaling by fgfr3
(R-HSA-5654741)
Signaling by fgfr4
(R-HSA-5654743)
Signaling by ntrk2 (trkb)
(R-HSA-9006115)
Signaling by ntrks
(R-HSA-166520)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Cytoplasm
(GO:0005737)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Identical protein binding
(GO:0042802)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)
Transmembrane receptor protein tyrosine kinase adaptor activity
(GO:0005068)

Other Information

Proteins

Fibroblast growth factor receptor substrate 3

Genular Protein ID: 3303155181

Symbol: FRS3_HUMAN

Name: Fibroblast growth factor receptor substrate 3

UniProtKB Accession Codes:

O43559 Q5T3D5

Database IDs:

Citations:

PubMed ID: 9660748

Title: Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins.

PubMed ID: 9660748

DOI: 10.1074/jbc.273.29.17987

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15485655

Title: SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.

PubMed ID: 15485655

DOI: 10.1016/j.bbrc.2004.09.152

PubMed ID: 15094036

Title: FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts.

PubMed ID: 15094036

DOI: 10.1016/s0014-5793(04)00287-x

Sequence Information:

Length: 492
Mass: 54462
Checksum: F06BFC662B531765
Sequence:

MGSCCSCLNR DSVPDNHPTK FKVTNVDDEG VELGSGVMEL TQSELVLHLH RREAVRWPYL 
CLRRYGYDSN LFSFESGRRC QTGQGIFAFK CSRAEEIFNL LQDLMQCNSI NVMEEPVIIT 
RNSHPAELDL PRAPQPPNAL GYTVSSFSNG CPGEGPRFSA PRRLSTSSLR HPSLGEESTH 
ALIAPDEQSH TYVNTPASED DHRRGRHCLQ PLPEGQAPFL PQARGPDQRD PQVFLQPGQV 
KFVLGPTPAR RHMVKCQGLC PSLHDPPHHN NNNEAPSECP AQPKCTYENV TGGLWRGAGW 
RLSPEEPGWN GLAHRRAALL HYENLPPLPP VWESQAQQLG GEAGDDGDSR DGLTPSSNGF 
PDGEEDETPL QKPTSTRAAI RSHGSFPVPL TRRRGSPRVF NFDFRRPGPE PPRQLNYIQV 
ELKGWGGDRP KGPQNPSSPQ APMPTTHPAR SSDSYAVIDL KKTVAMSNLQ RALPRDDGTA 
RKTRHNSTDL PL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FRS3

Associated with

Other Information

Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. PubMed ID: 9660748

The DNA sequence and analysis of human chromosome 6. PubMed ID: 14574404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334