CGB3 | ENSG00000104827 | NCBI 1082

Details for: CGB3

Gene ID: 1082

Symbol: CGB3

Ensembl ID: ENSG00000104827

Description: chorionic gonadotropin subunit beta 3

Associated with

Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Glycoprotein hormones
(R-HSA-209822)
Metabolism of proteins
(R-HSA-392499)
Peptide hormone biosynthesis
(R-HSA-209952)
Peptide hormone metabolism
(R-HSA-2980736)
Rna polymerase ii transcription
(R-HSA-73857)
Tfap2 (ap-2) family regulates transcription of growth factors and their receptors
(R-HSA-8866910)
Transcriptional regulation by the ap-2 (tfap2) family of transcription factors
(R-HSA-8864260)
Apoptotic process
(GO:0006915)
Cell-cell signaling
(GO:0007267)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Female gamete generation
(GO:0007292)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone-mediated signaling pathway
(GO:0009755)
Hormone activity
(GO:0005179)
Pituitary gonadotropin complex
(GO:0061696)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

Choriogonadotropin subunit beta 3

Genular Protein ID: 14877223

Symbol: CGB3_HUMAN

Name: Choriogonadotropin subunit beta 3

UniProtKB Accession Codes:

P0DN86 A1A5E0 B9ZVP5 P01233 Q13991 Q14000 Q3KPI3 Q3SY41 Q8WTT5 Q8WXL1 Q8WXL2 Q8WXL3 Q8WXL4

Database IDs:

Citations:

PubMed ID: 6774259

Title: The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region.

PubMed ID: 6774259

DOI: 10.1038/286684a0

PubMed ID: 6690982

Title: Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone.

PubMed ID: 6690982

DOI: 10.1038/307037a0

PubMed ID: 6194155

Title: The beta subunit of human chorionic gonadotropin is encoded by multiple genes.

PubMed ID: 6194155

DOI: 10.1016/s0021-9258(17)44254-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7462224

Title: The amino acid sequences of the prepeptides contained in the alpha and beta subunits of human choriogonadotropin.

PubMed ID: 7462224

DOI: 10.1016/s0021-9258(19)69881-9

PubMed ID: 2422163

Title: A map of the hCG beta-LH beta gene cluster.

PubMed ID: 2422163

DOI: 10.1016/s0021-9258(17)38469-7

PubMed ID: 11861891

Title: Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection.

PubMed ID: 11861891

DOI: 10.1093/oxfordjournals.molbev.a004085

PubMed ID: 1150658

Title: The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

PubMed ID: 1150658

DOI: 10.1016/s0021-9258(19)41303-3

PubMed ID: 4795659

Title: Human chorionic gonadotropin. Linear amino acid sequence of the beta subunit.

PubMed ID: 4795659

DOI: 10.1016/s0021-9258(19)43425-x

PubMed ID: 7240231

Title: Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.

PubMed ID: 7240231

DOI: 10.1016/s0021-9258(19)69030-7

PubMed ID: 1688430

Title: Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.

PubMed ID: 1688430

DOI: 10.1016/s0021-9258(19)40231-7

PubMed ID: 1820200

Title: Site-specific N-glycosylation of human chorionic gonadotrophin -- structural analysis of glycopeptides by one- and two-dimensional 1H NMR spectroscopy.

PubMed ID: 1820200

DOI: 10.1093/glycob/1.4.393

PubMed ID: 8202136

Title: Crystal structure of human chorionic gonadotropin.

PubMed ID: 8202136

DOI: 10.1038/369455a0

PubMed ID: 16123088

Title: Expression of beta-subunit of HCG genes during normal and failed pregnancy.

PubMed ID: 16123088

DOI: 10.1093/humrep/dei261

Sequence Information:

Length: 165
Mass: 17739
Checksum: 5598FB9E51A05748
Sequence:

MEMFQGLLLL LLLSMGGTWA SKEPLRPRCR PINATLAVEK EGCPVCITVN TTICAGYCPT 
MTRVLQGVLP ALPQVVCNYR DVRFESIRLP GCPRGVNPVV SYAVALSCQC ALCRRSTTDC 
GGPKDHPLTC DDPRFQDSSS SKAPPPSLPS PSRLPGPSDT PILPQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CGB3

Associated with

Other Information

The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region. PubMed ID: 6774259

Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. PubMed ID: 6690982

The beta subunit of human chorionic gonadotropin is encoded by multiple genes. PubMed ID: 6194155

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The amino acid sequences of the prepeptides contained in the alpha and beta subunits of human choriogonadotropin. PubMed ID: 7462224

A map of the hCG beta-LH beta gene cluster. PubMed ID: 2422163

Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection. PubMed ID: 11861891

The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit. PubMed ID: 1150658

Human chorionic gonadotropin. Linear amino acid sequence of the beta subunit. PubMed ID: 4795659

Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin. PubMed ID: 7240231

Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form. PubMed ID: 1688430

Site-specific N-glycosylation of human chorionic gonadotrophin -- structural analysis of glycopeptides by one- and two-dimensional 1H NMR spectroscopy. PubMed ID: 1820200

Crystal structure of human chorionic gonadotropin. PubMed ID: 8202136

Expression of beta-subunit of HCG genes during normal and failed pregnancy. PubMed ID: 16123088