Details for: SRCAP

Gene ID: 10847

Symbol: SRCAP

Ensembl ID: ENSG00000080603

Description: Snf2 related CREBBP activator protein

Associated with

Other Information

Genular Protein ID: 1665360694

Symbol: SRCAP_HUMAN

Name: Helicase SRCAP

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10347196

Title: Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

PubMed ID: 10347196

DOI: 10.1074/jbc.274.23.16370

PubMed ID: 10702287

Title: Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAP.

PubMed ID: 10702287

DOI: 10.1074/jbc.275.10.7184

PubMed ID: 11522779

Title: Regulation of cAMP-responsive element-binding protein-mediated transcription by the SNF2/SWI-related protein, SRCAP.

PubMed ID: 11522779

DOI: 10.1074/jbc.m103615200

PubMed ID: 11581372

Title: Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription.

PubMed ID: 11581372

DOI: 10.1128/jvi.75.21.10033-10040.2001

PubMed ID: 14500758

Title: SNF2-related CBP activator protein (SRCAP) functions as a coactivator of steroid receptor-mediated transcription through synergistic interactions with CARM-1 and GRIP-1.

PubMed ID: 14500758

DOI: 10.1210/me.2003-0208

PubMed ID: 14966270

Title: Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

PubMed ID: 14966270

DOI: 10.1128/mcb.24.5.1884-1896.2004

PubMed ID: 15647280

Title: The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.

PubMed ID: 15647280

DOI: 10.1074/jbc.m500001200

PubMed ID: 16024792

Title: Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathway.

PubMed ID: 16024792

DOI: 10.1128/mcb.25.15.6559-6569.2005

PubMed ID: 16634648

Title: Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes.

PubMed ID: 16634648

DOI: 10.1021/bi060043d

PubMed ID: 17617668

Title: The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters.

PubMed ID: 17617668

DOI: 10.1074/jbc.m703418200

PubMed ID: 22265015

Title: Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.

PubMed ID: 22265015

DOI: 10.1016/j.ajhg.2011.12.001

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 33909990

Title: Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature.

PubMed ID: 33909990

DOI: 10.1016/j.ajhg.2021.04.008

Sequence Information:

  • Length: 3230
  • Mass: 343555
  • Checksum: 3CFB74C7BDFBEAD0
  • Sequence:
  • MQSSPSPAHP QLPVLQTQMV SDGMTGSNPV SPASSSSPAS SGAGGISPQH IAQDSSLDGP 
    PGPPDGATVP LEGFSLSQAA DLANKGPKWE KSHAEIAEQA KHEAEIETRI AELRKEGFWS 
    LKRLPKVPEP PRPKGHWDYL CEEMQWLSAD FAQERRWKRG VARKVVRMVI RHHEEQRQKE 
    ERARREEQAK LRRIASTMAK DVRQFWSNVE KVVQFKQQSR LEEKRKKALD LHLDFIVGQT 
    EKYSDLLSQS LNQPLTSSKA GSSPCLGSSS AASSPPPPAS RLDDEDGDFQ PQEDEEEDDE 
    ETIEVEEQQE GNDAEAQRRE IELLRREGEL PLEELLRSLP PQLLEGPSSP SQTPSSHDSD 
    TRDGPEEGAE EEPPQVLEIK PPPSAVTQRN KQPWHPDEDD EEFTANEEEA EDEEDTIAAE 
    EQLEGEVDHA MELSELAREG ELSMEELLQQ YAGAYAPGSG SSEDEDEDEV DANSSDCEPE 
    GPVEAEEPPQ EDSSSQSDSV EDRSEDEEDE HSEEEETSGS SASEESESEE SEDAQSQSQA 
    DEEEEDDDFG VEYLLARDEE QSEADAGSGP PTPGPTTLGP KKEITDIAAA AESLQPKGYT 
    LATTQVKTPI PLLLRGQLRE YQHIGLDWLV TMYEKKLNGI LADEMGLGKT IQTISLLAHL 
    ACEKGNWGPH LIIVPTSVML NWEMELKRWC PSFKILTYYG AQKERKLKRQ GWTKPNAFHV 
    CITSYKLVLQ DHQAFRRKNW RYLILDEAQN IKNFKSQRWQ SLLNFNSQRR LLLTGTPLQN 
    SLMELWSLMH FLMPHVFQSH REFKEWFSNP LTGMIEGSQE YNEGLVKRLH KVLRPFLLRR 
    VKVDVEKQMP KKYEHVIRCR LSKRQRCLYD DFMAQTTTKE TLATGHFMSV INILMQLRKV 
    CNHPNLFDPR PVTSPFITPG ICFSTASLVL RATDVHPLQR IDMGRFDLIG LEGRVSRYEA 
    DTFLPRHRLS RRVLLEVATA PDPPPRPKPV KMKVNRMLQP VPKQEGRTVV VVNNPRAPLG 
    PVPVRPPPGP ELSAQPTPGP VPQVLPASLM VSASPAGPPL IPASRPPGPV LLPPLQPNSG 
    SLPQVLPSPL GVLSGTSRPP TPTLSLKPTP PAPVRLSPAP PPGSSSLLKP LTVPPGYTFP 
    PAAATTTSTT TATATTTAVP APTPAPQRLI LSPDMQARLP SGEVVSIGQL ASLAQRPVAN 
    AGGSKPLTFQ IQGNKLTLTG AQVRQLAVGQ PRPLQRNVVH LVSAGGQHHL ISQPAHVALI 
    QAVAPTPGPT PVSVLPSSTP STTPAPTGLS LPLAANQVPP TMVNNTGVVK IVVRQAPRDG 
    LTPVPPLAPA PRPPSSGLPA VLNPRPTLTP GRLPTPTLGT ARAPMPTPTL VRPLLKLVHS 
    PSPEVSASAP GAAPLTISSP LHVPSSLPGP ASSPMPIPNS SPLASPVSST VSVPLSSSLP 
    ISVPTTLPAP ASAPLTIPIS APLTVSASGP ALLTSVTPPL APVVPAAPGP PSLAPSGASP 
    SASALTLGLA TAPSLSSSQT PGHPLLLAPT SSHVPGLNST VAPACSPVLV PASALASPFP 
    SAPNPAPAQA SLLAPASSAS QALATPLAPM AAPQTAILAP SPAPPLAPLP VLAPSPGAAP 
    VLASSQTPVP VMAPSSTPGT SLASASPVPA PTPVLAPSST QTMLPAPVPS PLPSPASTQT 
    LALAPALAPT LGGSSPSQTL SLGTGNPQGP FPTQTLSLTP ASSLVPTPAQ TLSLAPGPPL 
    GPTQTLSLAP APPLAPASPV GPAPAHTLTL APASSSASLL APASVQTLTL SPAPVPTLGP 
    AAAQTLALAP ASTQSPASQA SSLVVSASGA APLPVTMVSR LPVSKDEPDT LTLRSGPPSP 
    PSTATSFGGP RPRRQPPPPP RSPFYLDSLE EKRKRQRSER LERIFQLSEA HGALAPVYGT 
    EVLDFCTLPQ PVASPIGPRS PGPSHPTFWT YTEAAHRAVL FPQQRLDQLS EIIERFIFVM 
    PPVEAPPPSL HACHPPPWLA PRQAAFQEQL ASELWPRARP LHRIVCNMRT QFPDLRLIQY 
    DCGKLQTLAV LLRQLKAEGH RVLIFTQMTR MLDVLEQFLT YHGHLYLRLD GSTRVEQRQA 
    LMERFNADKR IFCFILSTRS GGVGVNLTGA DTVVFYDSDW NPTMDAQAQD RCHRIGQTRD 
    VHIYRLISER TVEENILKKA NQKRMLGDMA IEGGNFTTAY FKQQTIRELF DMPLEEPSSS 
    SVPSAPEEEE ETVASKQTHI LEQALCRAED EEDIRAATQA KAEQVAELAE FNENDGFPAG 
    EGEEAGRPGA EDEEMSRAEQ EIAALVEQLT PIERYAMKFL EASLEEVSRE ELKQAEEQVE 
    AARKDLDQAK EEVFRLPQEE EEGPGAGDES SCGTGGGTHR RSKKAKAPER PGTRVSERLR 
    GARAETQGAN HTPVISAHQT RSTTTPPRCS PARERVPRPA PRPRPTPASA PAAIPALVPV 
    PVSAPVPISA PNPITILPVH ILPSPPPPSQ IPPCSSPACT PPPACTPPPA HTPPPAQTCL 
    VTPSSPLLLG PPSVPISASV TNLPLGLRPE AELCAQALAS PESLELASVA SSETSSLSLV 
    PPKDLLPVAV EILPVSEKNL SLTPSAPSLT LEAGSIPNGQ EQEAPDSAEG TTLTVLPEGE 
    ELPLCVSESN GLELPPSAAS DEPLQEPLEA DRTSEELTEA KTPTSSPEKP QELVTAEVAA 
    PSTSSSATSS PEGPSPARPP RRRTSADVEI RGQGTGRPGQ PPGPKVLRKL PGRLVTVVEE 
    KELVRRRRQQ RGAASTLVPG VSETSASPGS PSVRSMSGPE SSPPIGGPCE AAPSSSLPTP 
    PQQPFIARRH IELGVTGGGS PENGDGALLA ITPPAVKRRR GRPPKKNRSP ADAGRGVDEA 
    PSSTLKGKTN GADPVPGPET LIVADPVLEP QLIPGPQPLG PQPVHRPNPL LSPVEKRRRG 
    RPPKARDLPI PGTISSAGDG NSESRTQPPP HPSPLTPLPP LLVCPTATVA NTVTTVTIST 
    SPPKRKRGRP PKNPPSPRPS QLPVLDRDST SVLESCGLGR RRQPQGQGES EGSSSDEDGS 
    RPLTRLARLR LEAEGMRGRK SGGSMVVAVI QDDLDLADSG PGGLELTPPV VSLTPKLRST 
    RLRPGSLVPP LETEKLPRKR AGAPVGGSPG LAKRGRLQPP SPLGPEGSVE ESEAEASGEE 
    EEGDGTPRRR PGPRRLVGTT NQGDQRILRS SAPPSLAGPA VSHRGRKAKT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.