Details for: PGRMC1

Gene ID: 10857

Symbol: PGRMC1

Ensembl ID: ENSG00000101856

Description: progesterone receptor membrane component 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.49
    Marker Score: 61,971
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.75
    Marker Score: 5,583
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.73
    Marker Score: 3,302
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.7
    Marker Score: 17,537
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 2.62
    Marker Score: 2,231
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.53
    Marker Score: 86,232
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.5
    Marker Score: 32,935
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.49
    Marker Score: 5,194
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 2.46
    Marker Score: 2,318
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.41
    Marker Score: 1,002
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.38
    Marker Score: 8,439
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.37
    Marker Score: 26,660
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 2.35
    Marker Score: 2,535
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.35
    Marker Score: 2,209
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.3
    Marker Score: 5,805
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.27
    Marker Score: 6,093
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.26
    Marker Score: 5,310
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.24
    Marker Score: 2,395
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.22
    Marker Score: 3,675
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 2.19
    Marker Score: 735
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.17
    Marker Score: 3,194
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 2.12
    Marker Score: 1,093
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.11
    Marker Score: 73,195
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.1
    Marker Score: 1,319
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.08
    Marker Score: 1,390
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.07
    Marker Score: 785
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 2.05
    Marker Score: 2,172
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.03
    Marker Score: 3,599
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 2.03
    Marker Score: 847
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.02
    Marker Score: 7,797
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2
    Marker Score: 6,295
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2
    Marker Score: 11,872
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.98
    Marker Score: 3,046
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.96
    Marker Score: 2,085
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.94
    Marker Score: 16,851
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.94
    Marker Score: 3,084
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.9
    Marker Score: 9,128
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.85
    Marker Score: 1,020
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.84
    Marker Score: 1,865
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.84
    Marker Score: 423
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 1.82
    Marker Score: 454
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.81
    Marker Score: 8,911
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.81
    Marker Score: 1,934
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 1.81
    Marker Score: 454
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.8
    Marker Score: 4,704
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 1.78
    Marker Score: 2,742
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.74
    Marker Score: 558
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.74
    Marker Score: 990
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.73
    Marker Score: 2,837
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.72
    Marker Score: 2,440
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.72
    Marker Score: 17,315
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.72
    Marker Score: 7,948
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 1.7
    Marker Score: 2,213
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.7
    Marker Score: 4,027
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.68
    Marker Score: 1,787
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.67
    Marker Score: 483
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 1.67
    Marker Score: 579
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.67
    Marker Score: 825
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.65
    Marker Score: 468
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.65
    Marker Score: 2,654
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.65
    Marker Score: 2,265
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.65
    Marker Score: 6,706
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.64
    Marker Score: 1,037
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.64
    Marker Score: 1,918
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.64
    Marker Score: 3,918
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.63
    Marker Score: 2,016
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.63
    Marker Score: 951
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.63
    Marker Score: 3,973
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.62
    Marker Score: 380
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.61
    Marker Score: 1,993
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.6
    Marker Score: 951
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.6
    Marker Score: 756
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.6
    Marker Score: 3,000
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.59
    Marker Score: 8,370
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.59
    Marker Score: 1,654
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.56
    Marker Score: 1,465
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.55
    Marker Score: 1,061
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.55
    Marker Score: 6,687
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.54
    Marker Score: 10,058
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.53
    Marker Score: 5,656
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.52
    Marker Score: 5,974
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.52
    Marker Score: 4,137
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.52
    Marker Score: 9,669
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.51
    Marker Score: 3,017
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.51
    Marker Score: 1,081
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.5
    Marker Score: 3,425
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.5
    Marker Score: 2,114
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.5
    Marker Score: 11,177
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.48
    Marker Score: 1,164
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.47
    Marker Score: 1,585
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.47
    Marker Score: 1,042
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.45
    Marker Score: 285
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.45
    Marker Score: 3,297
  • Cell Name: platelet (CL0000233)
    Fold Change: 1.45
    Marker Score: 656
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.45
    Marker Score: 545
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.41
    Marker Score: 526
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.41
    Marker Score: 1,103
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.41
    Marker Score: 12,115
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.38
    Marker Score: 4,736
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.36
    Marker Score: 4,469

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PGRMC1 is a transmembrane protein, comprising two distinct domains: a membrane-associated domain and a cytoplasmic domain. The membrane-associated domain is essential for ligand binding and transmembrane transport, while the cytoplasmic domain is involved in protein-protein interactions and signaling. PGRMC1 is highly expressed in various cell types, including cortical cells of the adrenal gland, GABAergic amacrine cells, and fibroblasts from different tissues. **Pathways and Functions:** PGRMC1 is implicated in numerous cellular processes, including: 1. **Heme biosynthesis**: PGRMC1 plays a crucial role in the biosynthesis of heme, a vital component of hemoglobin and other proteins. 2. **Immune system regulation**: PGRMC1 modulates immune responses, influencing the activity of neutrophils and the regulation of lipoprotein transport. 3. **Synaptic plasticity**: PGRMC1 is involved in the regulation of synaptic structure and function, particularly in neurons and glial cells. 4. **Amyloid-beta binding**: PGRMC1 interacts with amyloid-beta peptides, a hallmark of Alzheimer's disease, and may play a role in their clearance. 5. **Steroid hormone regulation**: PGRMC1 is a receptor for progesterone and other steroid hormones, influencing their cellular effects. **Clinical Significance:** PGRMC1's involvement in various diseases highlights its potential as a therapeutic target. Some of the conditions associated with PGRMC1 dysregulation include: 1. **Alzheimer's disease**: PGRMC1's interaction with amyloid-beta peptides suggests its potential as a therapeutic target for Alzheimer's disease treatment. 2. **Prostate cancer**: PGRMC1's expression in prostate cancer cells indicates its possible role in cancer progression and metastasis. 3. **Immune system disorders**: PGRMC1's involvement in immune system regulation suggests its potential as a therapeutic target for autoimmune diseases. 4. **Neurological disorders**: PGRMC1's role in synaptic plasticity and neuronal function may contribute to the pathogenesis of neurological disorders, such as Parkinson's disease and multiple sclerosis. In conclusion, PGRMC1 is a multifunctional protein with diverse roles in various cellular processes. Further research is essential to unravel the complexities of PGRMC1 and its potential applications in disease treatment and prevention. As an expert immunologist, it is crucial to continue exploring the intricacies of PGRMC1 to unlock its full therapeutic potential.

Genular Protein ID: 568808419

Symbol: PGRC1_HUMAN

Name: Membrane-associated progesterone receptor component 1

UniProtKB Accession Codes:

O00264 B7Z1L3 Q9UGJ9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9705155

Title: Cloning and tissue expression of two putative steroid membrane receptors.

PubMed ID: 9705155

DOI: 10.1515/bchm.1998.379.7.907

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11697142

Title: The human membrane progesterone receptor gene: genomic structure and promoter analysis.

PubMed ID: 11697142

DOI: 10.3109/10425170109042047

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21730960

Title: Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

PubMed ID: 21730960

DOI: 10.1038/ncomms1386

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22292588

Title: S2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling.

PubMed ID: 22292588

DOI: 10.1517/17425255.2012.658367

PubMed ID: 23763432

Title: Nonclassical progesterone signalling molecules in the nervous system.

PubMed ID: 23763432

DOI: 10.1111/jne.12060

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23793472

Title: Expression patterns of progesterone receptor membrane components 1 and 2 in endometria from women with and without endometriosis.

PubMed ID: 23793472

DOI: 10.1177/1933719113492208

PubMed ID: 25675345

Title: Spectroscopic and mutagenesis studies of human PGRMC1.

PubMed ID: 25675345

DOI: 10.1021/bi501177e

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27599036

Title: A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase.

PubMed ID: 27599036

DOI: 10.1021/acs.biochem.6b00756

PubMed ID: 28396637

Title: Membrane associated progesterone receptors: promiscuous proteins with pleiotropic functions - focus on interactions with cytochromes P450.

PubMed ID: 28396637

DOI: 10.3389/fphar.2017.00159

PubMed ID: 28559337

Title: Identification of the gene that codes for the sigma2 receptor.

PubMed ID: 28559337

DOI: 10.1073/pnas.1705154114

PubMed ID: 28007569

Title: Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1.

PubMed ID: 28007569

DOI: 10.1016/j.phrs.2016.12.023

PubMed ID: 36213313

Title: Mass spectrometric analysis of chondroitin sulfate-linked peptides.

PubMed ID: 36213313

DOI: 10.1007/s42485-022-00092-3

PubMed ID: 37453717

Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.

PubMed ID: 37453717

DOI: 10.1016/j.mcpro.2023.100617

PubMed ID: 26988023

Title: Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.

PubMed ID: 26988023

DOI: 10.1038/ncomms11030

Sequence Information:

  • Length: 195
  • Mass: 21671
  • Checksum: CCD5E802E1C9E604
  • Sequence:
    • MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ PAASGDSDDD 
EPPPLPRLKR RDFTPAELRR FDGVQDPRIL MAINGKVFDV TKGRKFYGPE GPYGVFAGRD 
ASRGLATFCL DKEALKDEYD DLSDLTAAQQ ETLSDWESQF TFKYHHVGKL LKEGEEPTVY 
SDEEEPKDES ARKND

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.