Details for: LILRB1

Gene ID: 10859

Symbol: LILRB1

Ensembl ID: ENSG00000104972

Description: leukocyte immunoglobulin like receptor B1

Associated with

  • Adaptive immune system
    (R-HSA-1280218)
  • Immune system
    (R-HSA-168256)
  • Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
    (R-HSA-198933)
  • Adaptive immune response
    (GO:0002250)
  • Amyloid-beta binding
    (GO:0001540)
  • Cellular response to lipopolysaccharide
    (GO:0071222)
  • Cytokine-mediated signaling pathway
    (GO:0019221)
  • Cytoplasm
    (GO:0005737)
  • Defense response to virus
    (GO:0051607)
  • Dendritic cell differentiation
    (GO:0097028)
  • External side of plasma membrane
    (GO:0009897)
  • Extracellular region
    (GO:0005576)
  • Fc receptor mediated inhibitory signaling pathway
    (GO:0002774)
  • Hla-a specific inhibitory mhc class i receptor activity
    (GO:0030107)
  • Hla-b specific inhibitory mhc class i receptor activity
    (GO:0030109)
  • Immune response-inhibiting cell surface receptor signaling pathway
    (GO:0002767)
  • Inhibitory mhc class i receptor activity
    (GO:0032396)
  • Mhc class ib protein binding
    (GO:0023029)
  • Mhc class ib protein complex binding
    (GO:0023025)
  • Mhc class ib receptor activity
    (GO:0032394)
  • Mhc class i protein binding
    (GO:0042288)
  • Mhc class i receptor activity
    (GO:0032393)
  • Negative regulation of alpha-beta t cell activation
    (GO:0046636)
  • Negative regulation of calcium ion transport
    (GO:0051926)
  • Negative regulation of cd8-positive, alpha-beta t cell activation
    (GO:2001186)
  • Negative regulation of cell cycle
    (GO:0045786)
  • Negative regulation of cytokine production involved in immune response
    (GO:0002719)
  • Negative regulation of dendritic cell apoptotic process
    (GO:2000669)
  • Negative regulation of dendritic cell differentiation
    (GO:2001199)
  • Negative regulation of endocytosis
    (GO:0045806)
  • Negative regulation of interferon-beta production
    (GO:0032688)
  • Negative regulation of interleukin-10 production
    (GO:0032693)
  • Negative regulation of interleukin-12 production
    (GO:0032695)
  • Negative regulation of mononuclear cell proliferation
    (GO:0032945)
  • Negative regulation of natural killer cell mediated cytotoxicity
    (GO:0045953)
  • Negative regulation of osteoclast development
    (GO:2001205)
  • Negative regulation of serotonin secretion
    (GO:0014063)
  • Negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
    (GO:2001189)
  • Negative regulation of t cell mediated cytotoxicity
    (GO:0001915)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Negative regulation of transforming growth factor beta production
    (GO:0071635)
  • Negative regulation of tumor necrosis factor production
    (GO:0032720)
  • Negative regulation of type ii interferon production
    (GO:0032689)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of defense response to virus by host
    (GO:0002230)
  • Positive regulation of gamma-delta t cell activation involved in immune response
    (GO:2001193)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of macrophage cytokine production
    (GO:0060907)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of type ii interferon production
    (GO:0032729)
  • Protein binding
    (GO:0005515)
  • Protein homodimerization activity
    (GO:0042803)
  • Protein phosphatase 1 binding
    (GO:0008157)
  • Receptor internalization
    (GO:0031623)
  • Response to virus
    (GO:0009615)
  • Sh2 domain binding
    (GO:0042169)
  • Signal transduction
    (GO:0007165)
  • T cell proliferation involved in immune response
    (GO:0002309)

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 4.75
    Marker Score: 3,349
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 2.19
    Marker Score: 4,258
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.07
    Marker Score: 8,597
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.99
    Marker Score: 1,986
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 1.89
    Marker Score: 1,150
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 1.68
    Marker Score: 4,044
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6
    Marker Score: 1,163
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.58
    Marker Score: 1,974
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.48
    Marker Score: 82,962
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.47
    Marker Score: 1,475
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.4
    Marker Score: 16,223
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.25
    Marker Score: 849
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 1.24
    Marker Score: 1,188
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.17
    Marker Score: 798
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.16
    Marker Score: 481
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.15
    Marker Score: 416
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,803
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.14
    Marker Score: 7,576
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.1
    Marker Score: 2,734
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.05
    Marker Score: 1,072
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,812
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,037
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,407
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 503
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.97
    Marker Score: 403
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 456
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,412
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 368
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,739
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.9
    Marker Score: 415
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 321
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,280
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.83
    Marker Score: 632
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.8
    Marker Score: 398
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.79
    Marker Score: 273
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,266
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 705
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 391
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.71
    Marker Score: 456
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 176
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 0.68
    Marker Score: 783
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.68
    Marker Score: 1,096
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.67
    Marker Score: 17,146
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.66
    Marker Score: 1,893
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 0.65
    Marker Score: 394
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.65
    Marker Score: 952
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.65
    Marker Score: 1,674
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.64
    Marker Score: 1,907
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.64
    Marker Score: 1,865
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 0.62
    Marker Score: 556
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.61
    Marker Score: 218
  • Cell Name: centroblast (CL0009112)
    Fold Change: 0.61
    Marker Score: 300
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 445
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.55
    Marker Score: 331
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.54
    Marker Score: 172
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.54
    Marker Score: 5,498
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.53
    Marker Score: 354
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.53
    Marker Score: 3,207
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.52
    Marker Score: 304
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.51
    Marker Score: 340
  • Cell Name: plasmacytoid dendritic cell, human (CL0001058)
    Fold Change: 0.51
    Marker Score: 133
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.49
    Marker Score: 369
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.48
    Marker Score: 638
  • Cell Name: Langerhans cell (CL0000453)
    Fold Change: 0.47
    Marker Score: 141
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.45
    Marker Score: 193
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 0.44
    Marker Score: 416
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.43
    Marker Score: 482
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.42
    Marker Score: 219
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.42
    Marker Score: 238
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 0.42
    Marker Score: 409
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 0.41
    Marker Score: 1,129
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.4
    Marker Score: 400
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.4
    Marker Score: 213
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.39
    Marker Score: 104
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.39
    Marker Score: 510
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 0.39
    Marker Score: 332
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 0.39
    Marker Score: 1,226
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.38
    Marker Score: 86
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 0.38
    Marker Score: 132
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 0.37
    Marker Score: 121
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.37
    Marker Score: 118
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 0.36
    Marker Score: 148
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.36
    Marker Score: 3,021
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.35
    Marker Score: 244
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 0.35
    Marker Score: 84
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.34
    Marker Score: 119
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.34
    Marker Score: 325
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.34
    Marker Score: 329
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.33
    Marker Score: 168
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 0.33
    Marker Score: 216
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.33
    Marker Score: 393
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 0.32
    Marker Score: 85
  • Cell Name: colon macrophage (CL0009038)
    Fold Change: 0.32
    Marker Score: 87
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.31
    Marker Score: 432
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.31
    Marker Score: 271
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.31
    Marker Score: 906
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 0.31
    Marker Score: 640
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.3
    Marker Score: 84
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.3
    Marker Score: 844

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Inhibitory receptor**: LILRB1 acts as an inhibitory receptor, which means that it can suppress the activation of immune cells in response to certain stimuli. 2. **Surface receptor**: LILRB1 is a surface receptor, which allows it to interact with its ligands and regulate the immune response. 3. **Monocyte and dendritic cell expression**: LILRB1 is expressed on the surface of monocytes and dendritic cells, which are key players in the initiation and regulation of the immune response. 4. **Negative regulation of immune responses**: LILRB1 can negatively regulate the immune response by controlling the production of cytokines, the activation of T cells, and the phagocytosis of pathogens. 5. **Positive regulation of immune responses**: LILRB1 can also positively regulate the immune response by promoting the activation of gamma-delta T cells and the production of cytokines. **Pathways and Functions** 1. **Adaptive immune response**: LILRB1 plays a role in regulating the adaptive immune response by controlling the activation of T cells and the production of cytokines. 2. **Inhibitory MHC class I receptor activity**: LILRB1 acts as an inhibitory MHC class I receptor, which means that it can suppress the activation of T cells in response to specific antigens. 3. **Cytokine-mediated signaling pathway**: LILRB1 can regulate the production of cytokines by controlling the signaling pathways that lead to their production. 4. **Dendritic cell differentiation**: LILRB1 can regulate the differentiation of dendritic cells by controlling the production of cytokines and the activation of T cells. 5. **Immune system regulation**: LILRB1 plays a role in regulating the immune system by controlling the activity of various immune cells and the production of cytokines. **Clinical Significance** 1. **Autoimmune diseases**: LILRB1 has been implicated in the pathogenesis of several autoimmune diseases, including multiple sclerosis and rheumatoid arthritis. 2. **Cancer**: LILRB1 has been shown to be overexpressed in several types of cancer, including melanoma and lung cancer. 3. **Infectious diseases**: LILRB1 can play a role in regulating the immune response to infectious diseases, such as HIV and tuberculosis. 4. **Immunotherapy**: LILRB1 has been identified as a potential target for immunotherapy, which aims to modulate the immune response to treat diseases such as cancer and autoimmune disorders. In conclusion, LILRB1 is an important regulator of the immune response, and its dysregulation has been implicated in several diseases. Further research is needed to fully understand the role of LILRB1 in the immune system and to explore its potential as a therapeutic target.

Genular Protein ID: 1153032655

Symbol: LIRB1_HUMAN

Name: Leukocyte immunoglobulin-like receptor subfamily B member 1

UniProtKB Accession Codes:

Q8NHL6 A2IXV4 A8MXT0 O75024 O75025 Q8NHJ9 Q8NHK0

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EMDB 1 Ensembl 5 EvolutionaryTrace 1 GO 54 Gene3D 1 GeneCards 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 25 PDBsum 16 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 1 RefSeq 6 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9259559

Title: A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors.

PubMed ID: 9259559

DOI: 10.1016/s0960-9822(06)00263-6

PubMed ID: 9285411

Title: A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules.

PubMed ID: 9285411

DOI: 10.1016/s1074-7613(00)80529-4

PubMed ID: 10941837

Title: Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4.

PubMed ID: 10941837

DOI: 10.1007/s002510000183

PubMed ID: 19658091

Title: Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes.

PubMed ID: 19658091

DOI: 10.1002/eji.200839080

PubMed ID: 20600445

Title: LILRB1 polymorphism and surface phenotypes of natural killer cells.

PubMed ID: 20600445

DOI: 10.1016/j.humimm.2010.06.015

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9842885

Title: The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes.

PubMed ID: 9842885

DOI: 10.1002/(sici)1521-4141(199811)28:11<3423::aid-immu3423>3.0.co;2-2

PubMed ID: 10591185

Title: The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18.

PubMed ID: 10591185

DOI: 10.1016/s1074-7613(00)80135-1

PubMed ID: 11907092

Title: Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor.

PubMed ID: 11907092

DOI: 10.4049/jimmunol.168.7.3351

PubMed ID: 16455647

Title: Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer.

PubMed ID: 16455647

DOI: 10.1074/jbc.m512305200

PubMed ID: 19304799

Title: HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells.

PubMed ID: 19304799

DOI: 10.1073/pnas.0901173106

PubMed ID: 20448110

Title: Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway.

PubMed ID: 20448110

DOI: 10.1182/blood-2009-07-234872

PubMed ID: 24453251

Title: Binding of HLA-G to ITIM-bearing Ig-like transcript 2 receptor suppresses B cell responses.

PubMed ID: 24453251

DOI: 10.4049/jimmunol.1300438

PubMed ID: 29262349

Title: Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors.

PubMed ID: 29262349

DOI: 10.1016/j.immuni.2017.11.018

PubMed ID: 28636952

Title: Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

PubMed ID: 28636952

DOI: 10.1016/j.immuni.2017.06.002

PubMed ID: 11114384

Title: Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2).

PubMed ID: 11114384

DOI: 10.1016/s1074-7613(00)00071-6

Sequence Information:

  • Length: 650
  • Mass: 70819
  • Checksum: 549196EA4ED2767C
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTALWI TRIPQELVKK GQFPIPSITW EHAGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VILQCDSQVA FDGFSLCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
GPSGGPSSPT TGPTSTSGPE DQPLTPTGSD PQSGLGRHLG VVIGILVAVI LLLLLLLLLF 
LILRHRRQGK HWTSTQRKAD FQHPAGAVGP EPTDRGLQWR SSPAADAQEE NLYAAVKHTQ 
PEDGVEMDTR SPHDEDPQAV TYAEVKHSRP RREMASPPSP LSGEFLDTKD RQAEEDRQMD 
TEAAASEAPQ DVTYAQLHSL TLRREATEPP PSQEGPSPAV PSIYATLAIH

Genular Protein ID: 121305181

Symbol: A0A087WSV6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WSV6

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 3 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 652
  • Mass: 71047
  • Checksum: 0A1F1E01C09F58FC
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
GPSGGPSSPT TGPTSTSAGP EDQPLTPTGS DPQSGLGRHL GVVIGILVAV ILLLLLLLLL 
FLILRHRRQG KHWTSTQRKA DFQHPAGAVG PEPTDRGLQW RSSPAADAQE ENLYAAVKHT 
QPEDGVEMDT RQSPHDEDPQ AVTYAEVKHS RPRREMASPP SPLSGEFLDT KDRQAEEDRQ 
MDTEAAASEA PQDVTYAQLH SLTLRREATE PPPSQEGPSP AVPSIYATLA IH

Genular Protein ID: 159907260

Symbol: A8MVE2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8MVE2

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 634
  • Mass: 69462
  • Checksum: 7917B74BD4FC8721
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
AGPEDQPLTP TGSDPQSGLG RHLGVVIGIL VAVILLLLLL LLLFLILRHR RQGKHWTSTQ 
RKADFQHPAG AVGPEPTDRG LQWRSSPAAD AQEENLYAAV KHTQPEDGVE MDTRSPHDED 
PQAVTYAEVK HSRPRREMAS PPSPLSGEFL DTKDRQAEED RQMDTEAAAS EAPQDVTYAQ 
LHSLTLRREA TEPPPSQEGP SPAVPSIYAT LAIH

Genular Protein ID: 332948196

Symbol: D9IDM5_HUMAN

Name: N/A

UniProtKB Accession Codes:

D9IDM5

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 20600445

Title: LILRB1 polymorphism and surface phenotypes of natural killer cells.

PubMed ID: 20600445

DOI: 10.1016/j.humimm.2010.06.015

Sequence Information:

  • Length: 651
  • Mass: 70976
  • Checksum: 82F752D3CE2DA351
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
GPSGGPSSPT TGPTSTSGPE DQPLTPTGSD PQSGLGRHLG VVIGILVAVI LLLLLLLLLF 
LILRHRRQGK HWTSTQRKAD FQHPAGAVGP EPTDRGLQWR SSPAADAQEE NLYAAVKHTQ 
PEDGVEMDTR QSPHDEDPQA VTYAEVKHSR PRREMASPPS PLSGEFLDTK DRQAEEDRQM 
DTEAAASEAP QDVTYAQLHS LTLRREATEP PPSQEGPSPA VPSIYATLAI H

Genular Protein ID: 2528621575

Symbol: A0A0B4J1W1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0B4J1W1

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 KEGG 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 2 SAM 3 SMART 2 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 650
  • Mass: 70847
  • Checksum: D5924C5782B386BB
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
GPSGGPSSPT TGPTSTSGPE DQPLTPTGSD PQSGLGRHLG VVIGILVAVI LLLLLLLLLF 
LILRHRRQGK HWTSTQRKAD FQHPAGAVGP EPTDRGLQWR SSPAADAQEE NLYAAVKHTQ 
PEDGVEMDTR SPHDEDPQAV TYAEVKHSRP RREMASPPSP LSGEFLDTKD RQAEEDRQMD 
TEAAASEAPQ DVTYAQLHSL TLRREATEPP PSQEGPSPAV PSIYATLAIH

Genular Protein ID: 2038468171

Symbol: A0A087WSX8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WSX8

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 651
  • Mass: 70918
  • Checksum: CDDE9E5930482B56
  • Sequence:
    • MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL 
YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG 
AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA 
IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE 
TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA 
HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE 
GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS 
GPSGGPSSPT TGPTSTSAGP EDQPLTPTGS DPQSGLGRHL GVVIGILVAV ILLLLLLLLL 
FLILRHRRQG KHWTSTQRKA DFQHPAGAVG PEPTDRGLQW RSSPAADAQE ENLYAAVKHT 
QPEDGVEMDT RSPHDEDPQA VTYAEVKHSR PRREMASPPS PLSGEFLDTK DRQAEEDRQM 
DTEAAASEAP QDVTYAQLHS LTLRREATEP PPSQEGPSPA VPSIYATLAI H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.