Details for: USP20
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,967 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.38
Marker Score: 14,272 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.23
Marker Score: 11,648 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.21
Marker Score: 74,583 - Cell Name: germ cell (CL0000586)
Fold Change: 1.2
Marker Score: 2,105 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.19
Marker Score: 1,837 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.19
Marker Score: 10,212 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.18
Marker Score: 11,081 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.16
Marker Score: 42,765 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.15
Marker Score: 4,439 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.12
Marker Score: 1,242 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.08
Marker Score: 40,981 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,758 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1
Marker Score: 19,828 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,983 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.99
Marker Score: 14,807 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,402 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.96
Marker Score: 2,253 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.95
Marker Score: 7,264 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.95
Marker Score: 2,079 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,406 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.94
Marker Score: 566 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 483 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 438 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,721 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.9
Marker Score: 1,715 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.89
Marker Score: 3,709 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.88
Marker Score: 5,045 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,290 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.86
Marker Score: 3,561 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.82
Marker Score: 258 - Cell Name: neuron (CL0000540)
Fold Change: 0.82
Marker Score: 3,322 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.81
Marker Score: 341 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8
Marker Score: 12,557 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.8
Marker Score: 17,019 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.76
Marker Score: 1,230 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 570 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 374 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.72
Marker Score: 418 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.72
Marker Score: 3,004 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.7
Marker Score: 283 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.69
Marker Score: 222 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.68
Marker Score: 187 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 614 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 169 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.66
Marker Score: 943 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.62
Marker Score: 157 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.6
Marker Score: 726 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.59
Marker Score: 2,170 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.58
Marker Score: 784 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.58
Marker Score: 2,674 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 0.58
Marker Score: 1,589 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.56
Marker Score: 3,363 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.55
Marker Score: 168 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.55
Marker Score: 160 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.55
Marker Score: 1,050 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.54
Marker Score: 28,704 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 432 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.54
Marker Score: 468 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.53
Marker Score: 426 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.53
Marker Score: 567 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.52
Marker Score: 333 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.51
Marker Score: 161 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.49
Marker Score: 199 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.49
Marker Score: 562 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.49
Marker Score: 815 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.48
Marker Score: 153 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.48
Marker Score: 166 - Cell Name: interneuron (CL0000099)
Fold Change: 0.47
Marker Score: 216 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.46
Marker Score: 189 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.46
Marker Score: 220 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.46
Marker Score: 391 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.46
Marker Score: 269 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.46
Marker Score: 1,277 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.45
Marker Score: 307 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.43
Marker Score: 1,368 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.43
Marker Score: 765 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.42
Marker Score: 110 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.41
Marker Score: 381 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.41
Marker Score: 212 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.41
Marker Score: 269 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.4
Marker Score: 572 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.4
Marker Score: 1,563 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.4
Marker Score: 384 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.4
Marker Score: 249 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 0.4
Marker Score: 683 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.4
Marker Score: 261 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.4
Marker Score: 776 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.39
Marker Score: 340 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.39
Marker Score: 263 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.39
Marker Score: 77 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.39
Marker Score: 440 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 0.39
Marker Score: 955 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.39
Marker Score: 471 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.39
Marker Score: 3,842 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.39
Marker Score: 187 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.38
Marker Score: 2,457 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 0.38
Marker Score: 81 - Cell Name: Unknown (CL0000548)
Fold Change: 0.38
Marker Score: 277
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2523111887
Symbol: UBP20_HUMAN
Name: Ubiquitin carboxyl-terminal hydrolase 20
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12056827
Title: Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.
PubMed ID: 12056827
PubMed ID: 10231032
Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10231032
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10369878
Title: Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes.
PubMed ID: 10369878
DOI: 10.1093/hmg/8.7.1313
PubMed ID: 12865408
Title: Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
PubMed ID: 12865408
DOI: 10.1172/jci18348
PubMed ID: 15776016
Title: VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.
PubMed ID: 15776016
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19424180
Title: The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.
PubMed ID: 19424180
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23166351
Title: MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound beta(2)-adrenergic receptors.
PubMed ID: 23166351
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23486064
Title: USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.
PubMed ID: 23486064
DOI: 10.1038/nature11941
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 26839314
Title: Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of beta-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor kappaB (NFkappaB) Activation.
PubMed ID: 26839314
PubMed ID: 27801882
Title: USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.
PubMed ID: 27801882
DOI: 10.1038/cr.2016.125
PubMed ID: 29487085
Title: The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.
PubMed ID: 29487085
PubMed ID: 32354117
Title: The Deubiquitinating Enzyme USP20 Regulates the TNFalpha-Induced NF-kappaB Signaling Pathway through Stabilization of p62.
PubMed ID: 32354117
DOI: 10.3390/ijms21093116
PubMed ID: 33792613
Title: Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.
PubMed ID: 33792613
PubMed ID: 35063767
Title: The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
PubMed ID: 35063767
Sequence Information:
- Length: 914
- Mass: 102003
- Checksum: DC094570A396D20E
- Sequence:
MGDSRDLCPH LDSIGEVTKE DLLLKSKGTC QSCGVTGPNL WACLQVACPY VGCGESFADH STIHAQAKKH NLTVNLTTFR LWCYACEKEV FLEQRLAAPL LGSSSKFSEQ DSPPPSHPLK AVPIAVADEG ESESEDDDLK PRGLTGMKNL GNSCYMNAAL QALSNCPPLT QFFLECGGLV RTDKKPALCK SYQKLVSEVW HKKRPSYVVP TSLSHGIKLV NPMFRGYAQQ DTQEFLRCLM DQLHEELKEP VVATVALTEA RDSDSSDTDE KREGDRSPSE DEFLSCDSSS DRGEGDGQGR GGGSSQAETE LLIPDEAGRA ISEKERMKDR KFSWGQQRTN SEQVDEDADV DTAMAALDDQ PAEAQPPSPR SSSPCRTPEP DNDAHLRSSS RPCSPVHHHE GHAKLSSSPP RASPVRMAPS YVLKKAQVLS AGSRRRKEQR YRSVISDIFD GSILSLVQCL TCDRVSTTVE TFQDLSLPIP GKEDLAKLHS AIYQNVPAKP GACGDSYAAQ GWLAFIVEYI RRFVVSCTPS WFWGPVVTLE DCLAAFFAAD ELKGDNMYSC ERCKKLRNGV KYCKVLRLPE ILCIHLKRFR HEVMYSFKIN SHVSFPLEGL DLRPFLAKEC TSQITTYDLL SVICHHGTAG SGHYIAYCQN VINGQWYEFD DQYVTEVHET VVQNAEGYVL FYRKSSEEAM RERQQVVSLA AMREPSLLRF YVSREWLNKF NTFAEPGPIT NQTFLCSHGG IPPHKYHYID DLVVILPQNV WEHLYNRFGG GPAVNHLYVC SICQVEIEAL AKRRRIEIDT FIKLNKAFQA EESPGVIYCI SMQWFREWEA FVKGKDNEPP GPIDNSRIAQ VKGSGHVQLK QGADYGQISE ETWTYLNSLY GGGPEIAIRQ SVAQPLGPEN LHGEQKIEAE TRAV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.