Details for: HCST
Associated with
Other Information
Genular Protein ID: 1662083828
Symbol: HCST_HUMAN
Name: Hematopoietic cell signal transducer
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10528161
Title: KAP10, a novel transmembrane adapter protein genetically linked to DAP12 but with unique signaling properties.
PubMed ID: 10528161
PubMed ID: 10426994
Title: An activating immunoreceptor complex formed by NKG2D and DAP10.
PubMed ID: 10426994
PubMed ID: 11398969
Title: Molecular cloning and characterization of pig immunoreceptor DAP10 and NKG2D.
PubMed ID: 11398969
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11015446
Title: DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells.
PubMed ID: 11015446
PubMed ID: 11777960
Title: UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.
PubMed ID: 11777960
PubMed ID: 12740575
Title: NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway.
PubMed ID: 12740575
DOI: 10.1038/ni929
PubMed ID: 12740576
Title: NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.
PubMed ID: 12740576
DOI: 10.1038/ni930
PubMed ID: 15294961
Title: A Structural basis for the association of DAP12 with mouse, but not human, NKG2D.
PubMed ID: 15294961
PubMed ID: 16002667
Title: Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo.
PubMed ID: 16002667
PubMed ID: 16339517
Title: Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells.
PubMed ID: 16339517
PubMed ID: 15894612
Title: The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure.
PubMed ID: 15894612
PubMed ID: 16424177
Title: IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells.
PubMed ID: 16424177
PubMed ID: 16582911
Title: NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.
PubMed ID: 16582911
DOI: 10.1038/ni1325
PubMed ID: 18097042
Title: Regulation of human DAP10 gene expression in NK and T cells by Ap-1 transcription factors.
PubMed ID: 18097042
PubMed ID: 26221034
Title: Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family.
PubMed ID: 26221034
Sequence Information:
- Length: 93
- Mass: 9489
- Checksum: 97786F24F8A2EE44
- Sequence:
MIHLGHILFL LLLPVAAAQT TPGERSSLPA FYPGTSGSCS GCGSLSLPLL AGLVAADAVA SLLIVGAVFL CARPRRSPAQ EDGKVYINMP GRG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.