Details for: RAB10

Gene ID: 10890

Symbol: RAB10

Ensembl ID: ENSG00000084733

Description: RAB10, member RAS oncogene family

Associated with

Other Information

Genular Protein ID: 3156813418

Symbol: RAB10_HUMAN

Name: Ras-related protein Rab-10

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12450215

Title: Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues.

PubMed ID: 12450215

DOI: 10.3727/000000002783992406

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16641372

Title: Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.

PubMed ID: 16641372

DOI: 10.1091/mbc.e05-08-0799

PubMed ID: 19570034

Title: GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.

PubMed ID: 19570034

DOI: 10.1042/bj20090624

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20576682

Title: Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells.

PubMed ID: 20576682

DOI: 10.1152/ajprenal.00198.2010

PubMed ID: 20937701

Title: Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

PubMed ID: 20937701

DOI: 10.1083/jcb.201008051

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21248164

Title: Role of Rab GTPases in membrane traffic and cell physiology.

PubMed ID: 21248164

DOI: 10.1152/physrev.00059.2009

PubMed ID: 22908308

Title: Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes.

PubMed ID: 22908308

DOI: 10.1083/jcb.201111091

PubMed ID: 23263280

Title: Rab10 GTPase regulates ER dynamics and morphology.

PubMed ID: 23263280

DOI: 10.1038/ncb2647

PubMed ID: 24891604

Title: Rab18 and a Rab18 GEF complex are required for normal ER structure.

PubMed ID: 24891604

DOI: 10.1083/jcb.201403026

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26824392

Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

PubMed ID: 26824392

DOI: 10.7554/elife.12813

PubMed ID: 29125462

Title: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

PubMed ID: 29125462

DOI: 10.7554/elife.31012

PubMed ID: 28067790

Title: RAB10 Interacts with the Male Germ Cell-Specific GTPase-Activating Protein during Mammalian Spermiogenesis.

PubMed ID: 28067790

DOI: 10.3390/ijms18010097

PubMed ID: 29127255

Title: Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

PubMed ID: 29127255

DOI: 10.1042/bcj20170803

PubMed ID: 30398148

Title: A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.

PubMed ID: 30398148

DOI: 10.7554/elife.40202

PubMed ID: 29212815

Title: Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

PubMed ID: 29212815

DOI: 10.15252/embj.201798099

PubMed ID: 29562525

Title: Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease.

PubMed ID: 29562525

DOI: 10.3233/jad-180023

PubMed ID: 31540829

Title: Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.

PubMed ID: 31540829

DOI: 10.1016/j.chom.2019.08.017

PubMed ID: 30635421

Title: Crystal structure of the WD40 domain dimer of LRRK2.

PubMed ID: 30635421

DOI: 10.1073/pnas.1817889116

PubMed ID: 32344433

Title: GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR DeltaF508.

PubMed ID: 32344433

DOI: 10.1083/jcb.201811014

PubMed ID: 27552051

Title: bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.

PubMed ID: 27552051

DOI: 10.7554/elife.18675

Sequence Information:

  • Length: 200
  • Mass: 22541
  • Checksum: 7F02B8E8E46EE1E8
  • Sequence:
  • MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL 
    QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL 
    GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN 
    SENVDISSGG GVTGWKSKCC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.