Details for: MALT1

Gene ID: 10892

Symbol: MALT1

Ensembl ID: ENSG00000172175

Description: MALT1 paracaspase

Associated with

Other Information

Genular Protein ID: 400074567

Symbol: MALT1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10339464

Title: The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.

PubMed ID: 10339464

PubMed ID: 10523859

Title: A novel gene, MALT1 at 18q21, is involved in t(11;18)(q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue.

PubMed ID: 10523859

DOI: 10.1038/sj.onc.1203018

PubMed ID: 11090634

Title: Identification of paracaspases and metacaspases. Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.

PubMed ID: 11090634

DOI: 10.1016/s1097-2765(00)00094-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10610122

Title: API1-MALT1-MLT is involved in mucosa-associated lymphoid tissue lymphoma with t(11;18).(q21;q21).

PubMed ID: 10610122

PubMed ID: 10702396

Title: API2-MALT1 chimeric transcripts involved in mucosa-associated lymphoid tissue type lymphoma predict heterogeneous products.

PubMed ID: 10702396

DOI: 10.1016/s0002-9440(10)64948-6

PubMed ID: 11262391

Title: Bcl10 and MALT1, independent targets of chromosomal translocation in MALT lymphoma, cooperate in a novel NF-kappa B signaling pathway.

PubMed ID: 11262391

DOI: 10.1074/jbc.m009984200

PubMed ID: 15125833

Title: The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes.

PubMed ID: 15125833

DOI: 10.1016/s1097-2765(04)00236-9

PubMed ID: 14695475

Title: Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.

PubMed ID: 14695475

DOI: 10.1038/nature02273

PubMed ID: 16123224

Title: MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10.

PubMed ID: 16123224

DOI: 10.1182/blood-2004-12-4785

PubMed ID: 18264101

Title: The proteolytic activity of the paracaspase MALT1 is key in T cell activation.

PubMed ID: 18264101

DOI: 10.1038/ni1568

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24074955

Title: Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly.

PubMed ID: 24074955

DOI: 10.1016/j.molcel.2013.08.032

PubMed ID: 27113748

Title: The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.

PubMed ID: 27113748

DOI: 10.15252/embr.201642109

PubMed ID: 28628108

Title: Germline hypomorphic CARD11 mutations in severe atopic disease.

PubMed ID: 28628108

DOI: 10.1038/ng.3898

PubMed ID: 31133753

Title: N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.

PubMed ID: 31133753

DOI: 10.1038/s41564-019-0460-3

PubMed ID: 23727036

Title: A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.

PubMed ID: 23727036

DOI: 10.1016/j.jaci.2013.04.047

Sequence Information:

  • Length: 824
  • Mass: 92272
  • Checksum: 28AFB80DA025F8AB
  • Sequence:
  • MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL 
    AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ 
    LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV 
    HVKDAGFYVC RVNNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP 
    GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD 
    SKKVEIIIGR TDEAVECTED ELNNLGHPDN KEQTTDQPLA KDKVALLIGN MNYREHPKLK 
    APLVDVYELT NLLRQLDFKV VSLLDLTEYE MRNAVDEFLL LLDKGVYGLL YYAGHGYENF 
    GNSFMVPVDA PNPYRSENCL CVQNILKLMQ EKETGLNVFL LDMCRKRNDY DDTIPILDAL 
    KVTANIVFGY ATCQGAEAFE IQHSGLANGI FMKFLKDRLL EDKKITVLLD EVAEDMGKCH 
    LTKGKQALEI RSSLSEKRAL TDPIQGTEYS AESLVRNLQW AKAHELPESM CLKFDCGVQI 
    QLGFAAEFSN VMIIYTSIVY KPPEIIMCDA YVTDFPLDLD IDPKDANKGT PEETGSYLVS 
    KDLPKHCLYT RLSSLQKLKE HLVFTVCLSY QYSGLEDTVE DKQEVNVGKP LIAKLDMHRG 
    LGRKTCFQTC LMSNGPYQSS AATSGGAGHY HSLQDPFHGV YHSHPGNPSN VTPADSCHCS 
    RTPDAFISSF AHHASCHFSR SNVPVETTDE IPFSFSDRLR ISEK

Genular Protein ID: 1153707988

Symbol: A8K5S1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 824
  • Mass: 92244
  • Checksum: 026300CB9725FE7D
  • Sequence:
  • MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL 
    AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ 
    LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV 
    HVKDAGFYVC RANNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP 
    GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD 
    SKKVEIIIGR TDEAVECTED ELNNLGHPDN KEQTTDQPLA KDKVALLIGN MNYREHPKLK 
    APLVDVYELT NLLRQLDFKV VSLLDLTEYE MRNAVDEFLL LLDKGVYGLL YYAGHGYENF 
    GNSFMVPVDA PNPYRSENCL CVQNILKLMQ EKETGLNVFL LDMCRKRNDY DDTIPILDAL 
    KVTANIVFGY ATCQGAEAFE IQHSGLANGI FMKFLKDRLL EDKKITVLLD EVAEDMGKCH 
    LTKGKQALEI RSSLSEKRAL TDPIQGTEYS AESLVRNLQW AKAHELPESM CLKFDCGVQI 
    QLGFAAEFSN VMIIYTSIVY KPPEIIMCDA YVTDFPLDLD IDPKDANKGT PEETGSYLVS 
    KDLPKHCLYT RLSSLQKLKE HLVFTVCLSY QYSGLEDTVE DKQEVNVGKP LIAKLDMHRG 
    LGRKTCFQTC LMSNGPYQSS AATSGGAGHY HSLQDPFHGV YHSHPGNPSN VTPADSCHCS 
    RTPDAFISSF AHHASCHFSR SNVPVETTDE IPFSFSDRLR ISEK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.