Details for: BRD8

Gene ID: 10902

Symbol: BRD8

Ensembl ID: ENSG00000112983

Description: bromodomain containing 8

Associated with

Other Information

Genular Protein ID: 931823346

Symbol: BRD8_HUMAN

Name: Bromodomain-containing protein 8

UniProtKB Accession Codes:

Q9H0E9 O43178 Q15355 Q58AB0 Q59GN0 Q969M9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 6 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8611617

Title: Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain.

PubMed ID: 8611617

DOI: 10.1016/0167-4781(95)00239-1

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9368056

Title: Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein.

PubMed ID: 9368056

DOI: 10.1074/jbc.272.47.29834

PubMed ID: 12963728

Title: Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.

PubMed ID: 12963728

DOI: 10.1074/jbc.c300389200

PubMed ID: 10517671

Title: p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers.

PubMed ID: 10517671

DOI: 10.1210/mend.13.10.0353

PubMed ID: 15196461

Title: The highly conserved and multifunctional NuA4 HAT complex.

PubMed ID: 15196461

DOI: 10.1016/j.gde.2004.02.009

PubMed ID: 14966270

Title: Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

PubMed ID: 14966270

DOI: 10.1128/mcb.24.5.1884-1896.2004

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 24463511

Title: ANP32E is a histone chaperone that removes H2A.Z from chromatin.

PubMed ID: 24463511

DOI: 10.1038/nature12922

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1235
  • Mass: 135336
  • Checksum: 3738078C77FC17D1
  • Sequence:
    • MATGTGKHKL LSTGPTEPWS IREKLCLASS VMRSGDQNWV SVSRAIKPFA EPGRPPDWFS 
QKHCASQYSE LLETTETPKR KRGEKGEVVE TVEDVIVRKL TAERVEELKK VIKETQERYR 
RLKRDAELIQ AGHMDSRLDE LCNDIATKKK LEEEEAEVKR KATDAAYQAR QAVKTPPRRL 
PTVMVRSPID SASPGGDYPL GDLTPTTMEE ATSGVNESEM AVASGHLNST GVLLEVGGVL 
PMIHGGEIQQ TPNTVAASPA ASGAPTLSRL LEAGPTQFTT PLASFTTVAS EPPVKLVPPP 
VESVSQATIV MMPALPAPSS APAVSTTESV APVSQPDNCV PMEAVGDPHT VTVSMDSSEI 
SMIINSIKEE CFRSGVAEAP VGSKAPSIDG KEELDLAEKM DIAVSYTGEE LDFETVGDII 
AIIEDKVDDH PEVLDVAAVE AALSFCEEND DPQSLPGPWE HPIQQERDKP VPLPAPEMTV 
KQERLDFEET ENKGIHELVD IREPSAEIKV EPAEPEPVIS GAEIVAGVVP ATSMEPPELR 
SQDLDEELGS TAAGEIVEAD VAIGKGDETP LTNVKTEASP ESMLSPSHGS NPIEDPLEAE 
TQHKFEMSDS LKEESGTIFG SQIKDAPGED EEEDGVSEAA SLEEPKEEDQ GEGYLSEMDN 
EPPVSESDDG FSIHNATLQS HTLADSIPSS PASSQFSVCS EDQEAIQAQK IWKKAIMLVW 
RAAANHRYAN VFLQPVTDDI APGYHSIVQR PMDLSTIKKN IENGLIRSTA EFQRDIMLMF 
QNAVMYNSSD HDVYHMAVEM QRDVLEQIQQ FLATQLIMQT SESGISAKSL RGRDSTRKQD 
ASEKDSVPMG SPAFLLSLFM GHEWVWLDSE QDHPNDSELS NDCRSLFSSW DSSLDLDVGN 
WRETEDPEAE ELEESSPERE PSELLVGDGG SEESQEAARK ASHQNLLHFL SEVAYLMEPL 
CISSNESSEG CCPPSGTRQE GREIKASEGE RELCRETEEL SAKGDPLVAE KPLGENGKPE 
VASAPSVICT VQGLLTESEE GEAQQESKGE DQGEVYVSEM EDQPPSGECD DAFNIKETPL 
VDTLFSHATS SKLTDLSQDD PVQDHLLFKK TLLPVWKMIA SHRFSSPFLK PVSERQAPGY 
KDVVKRPMDL TSLKRNLSKG RIRTMAQFLR DLMLMFQNAV MYNDSDHHVY HMAVEMRQEV 
LEQIQVLNIW LDKRKGSSSL EGEPANPVDD GKPVF

Genular Protein ID: 940913525

Symbol: B4DMS9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DMS9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 657
  • Mass: 71502
  • Checksum: DB4651ED0B6D6CB4
  • Sequence:
    • MQELLSSFET IRIFLVESSS SYCFLFMCFL LTSFCVPLYM LGAPTLSRLL EAGPTQFTTP 
LASFTTVASE PPVKLVPPPV ESVSQATIVM MPALPAPSSA PAVSTTESVA PVSQPDNCVP 
MEAVGDPHTV TVSMDSSEIS MIINSIKEEC FRSGVAEAPV GSKAPSIDGK EELDLAEKMD 
IAVSYTGEEL DFETVGDIIA IIEDKVDDHP EVLDVAAVEA ALSFCEENDD PQSLPGPWEH 
PIQQERDKPV PLPAPEMTVK QERLDFEEME NKGIHELVDI REPSAEIKVE PAEPEPVISG 
AEIVAGVVPA TSMEPPELRS QDLDEELGST AAGEIVEADV AIGKGDETPL TNVKTEASPE 
SMLSPSHGSN PIEDPLEAET QHKFEMSDSL KEESGTIFGS QIKDAPGEDE EEDGVSEAAS 
LEEPKEEDQG EGYLSEMDNE PPVSESDDGF SIHNATLQSH TLADSIPSSP ASSQFSVCSE 
DQEAIQAQKI WKKAIMLVWR AAANHRYANV FLQPVTDDIA PGYHSIVQRP MDLSTIKKNI 
ENGLIRSTAE FQRDIMLMFQ NAVMYNSSDH DVYHMAVEMQ RDVLEQIQQF LATQLIMQTS 
ESGISAKSLR GRDSTRKQDA SEKDSVPMGS PAFLLSLFDG GTRGRRCAIE ADMKMKK

Genular Protein ID: 574351522

Symbol: B4DN43_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DN43

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 862
  • Mass: 93975
  • Checksum: FAB178C82F8F8D16
  • Sequence:
    • MVHPREAMFS IFCHEKWRSK LVRVSVSRAI KPFAEPGRPP DWFSQKHCAS QYSELLETTE 
TPKRKRGEKG EVVETVEDVI VRKLTAERVE ELKKVIKETQ ERYRRLKRDA ELIQAGHMDS 
RLDELCNDIA TKKKLEEEEA EVKRKATDAA YQARQAVKTP PRRLPTVMVR SPIDSASPGG 
DYPLGDLTPT TMEEATSGVN ESEMAVASGH LNSTGVLLEV GGVLPMIHGG EIQQTPNTVA 
ASPAASGAPT LSRLLEAGPT QFTTPLASFT TVASEPPVKL VPPPVESVSQ ATIVMMPALP 
APSSAPAVST TESVAPVSQP DNCVPMEAVG DPHTVTVSMD SSEISMIINS IKEECFRSGV 
AEAPVGSKAP SIDGKEELDL AEKMDIAVSY TGEELDFETV GDIIAIIEDK VDDHPEVLDV 
AAVEAALSFC EENDDPQSLP GPWEHPIQQE RDKPVPLPAP EMTVKQERLD FEETENKGIH 
ELVDIREPSA EIKVEPAEPE PVISGAEIVA GVVPATSMEP PELRSQDLDE ELGSTAAGEI 
VEADVAIGKG DETPLTNVKT EASPESMLSP SHGSNPIEDP LEAETQHKFE MSDSLKEESG 
TIFGSQIKDA PGEDEEEDGV SEAASLEEPK EEDQGEGYLS EMDNEPPVSE SDDGFSIHNA 
TLQSHTLADS IPSSPASSQF SVCSEDQEAI QAQKIWKKAI MLVWRAAANH RYANVFLQPV 
TDDIAPGYHS IVQRPMDLST IKKNIENGLI RSTAEFQRDI MLMFQNAVMY NSSDHDVYHM 
AVEMQRDVLE QIQQFLATQL IMQTSESGIS AKSLRGRDST RKQDASEKDS VPMGSPAFLL 
SLFDGGTRGR RCAIEADMKM KK

Genular Protein ID: 3782940923

Symbol: B4DEG9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DEG9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 837
  • Mass: 91080
  • Checksum: 9B8114830F28F1B5
  • Sequence:
    • MVHPREAMFS IFCHEKWRSK LHCASQYSEL LETTETPKRK RGEKGEVVET VEDVIVRKLT 
AERVEELKKV IKETQERYRR LKRDAELIQA GHMDSRLDEL CNDIATKKKL EEEEAEVKRK 
ATDAAYQARQ AVKTPPRRLP TVMVRSPIDS ASPGGDYPLG DLTPTTMEEA TSGVNESEMA 
VASGHLNSTG VLLEVGGVLP MIHGGEIQQT PNTVAASPAA SGAPTLSRLL EAGPTQFTTP 
LASFTTVASE PPVKLVPPPV ESVSQATIVM MPALPAPSSA PAVSTTESVA PVSQPDNCVP 
MEAVGDPHTV TVSMDSSEIS MIINSIKEEC FRSGVAEAPV GSKAPSIDGK EELDLAEKMD 
IAVSYTGEEL DFETVGDIIA IIEDKVDDHP EVLDVAAVEA ALSFCEENDD PQSLPGPWEH 
PIQQERDKPV PLPAPEMTVK QERLDFEETE NKGIHELVDI REPSAEIKVE PAEPEPVISG 
AEIVAGVVPA TSMEPPELRS QDLDEELGST AAGEIVEADV AIGKGDETPL TNVKTEASPE 
SMLSPSHGSN PIEDPLEAET QHKFEMSDSL KEESGTIFGS QIKDAPGEDE EEDGVSEAAS 
LEEPKEEDQG EGYLSEMGNE PPVSESDDGF SIHNATLQSH TLADSIPSSP ASSQFSVCSE 
DQEAIQAQKI WKKAIMLVWR AAANHRYANV FLQPVTDDIA PGYHSIVQRP MDLSTIKKNI 
ENGLIRSTAE FQRDIMLMFQ NAVMYNSSDH DVYHMAVEMQ RDVLEQIQQF LATQLIMQTS 
ESGISAKSLR GRDSTRKQDA SEKDSVPMGS PAFLLSLFDG GTRGRRCAIE ADMKMKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.