Details for: RNPS1

Gene ID: 10921

Symbol: RNPS1

Ensembl ID: ENSG00000205937

Description: RNA binding protein with serine rich domain 1

Associated with

Other Information

Genular Protein ID: 1923633468

Symbol: RNPS1_HUMAN

Name: RNA-binding protein with serine-rich domain 1

UniProtKB Accession Codes:

Q15287 A8K1P0 B4DDU8 B4DZU7 B7ZA17 O75308 Q32P25 Q8WY42 Q9NYG3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EPD 1 Ensembl 6 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 6 RefSeq 8 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8543184

Title: Identification and characterisation of a novel human RNA-binding protein.

PubMed ID: 8543184

DOI: 10.1016/0378-1119(95)00571-4

PubMed ID: 9580558

Title: The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinases in vivo.

PubMed ID: 9580558

DOI: 10.1242/jcs.111.11.1495

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10449421

Title: Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing.

PubMed ID: 10449421

DOI: 10.1093/emboj/18.16.4560

PubMed ID: 11118221

Title: The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.

PubMed ID: 11118221

DOI: 10.1093/emboj/19.24.6860

PubMed ID: 11477570

Title: Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation.

PubMed ID: 11477570

DOI: 10.1002/ijc.1391

PubMed ID: 11546874

Title: Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.

PubMed ID: 11546874

DOI: 10.1126/science.1062786

PubMed ID: 12944400

Title: An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation.

PubMed ID: 12944400

DOI: 10.1074/jbc.m306856200

PubMed ID: 14517304

Title: Nuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA processing and export via interaction with RNPS1.

PubMed ID: 14517304

DOI: 10.1128/mcb.23.20.7363-7376.2003

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 14752011

Title: Splicing enhances translation in mammalian cells: an additional function of the exon junction complex.

PubMed ID: 14752011

DOI: 10.1101/gad.1163204

PubMed ID: 14625303

Title: A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex.

PubMed ID: 14625303

DOI: 10.1074/jbc.m307692200

PubMed ID: 14729963

Title: Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.

PubMed ID: 14729963

DOI: 10.1128/mcb.24.3.1174-1187.2004

PubMed ID: 15684395

Title: Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

PubMed ID: 15684395

DOI: 10.1128/mcb.25.4.1446-1457.2005

PubMed ID: 16209946

Title: Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.

PubMed ID: 16209946

DOI: 10.1016/j.molcel.2005.08.012

PubMed ID: 12665594

Title: ASAP, a novel protein complex involved in RNA processing and apoptosis.

PubMed ID: 12665594

DOI: 10.1128/mcb.23.8.2981-2990.2003

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16314458

Title: Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.

PubMed ID: 16314458

DOI: 10.1261/rna.2155905

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17586820

Title: The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the nonsense mediated decay pathway.

PubMed ID: 17586820

DOI: 10.1093/nar/gkm461

PubMed ID: 19324961

Title: Assembly and mobility of exon-exon junction complexes in living cells.

PubMed ID: 19324961

DOI: 10.1261/rna.1387009

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20966198

Title: Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold.

PubMed ID: 20966198

DOI: 10.1261/rna.2304410

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22203037

Title: Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

PubMed ID: 22203037

DOI: 10.1128/mcb.06130-11

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 22388736

Title: The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex.

PubMed ID: 22388736

DOI: 10.1038/nsmb.2242

Sequence Information:

  • Length: 305
  • Mass: 34208
  • Checksum: 930C9D36C2486144
  • Sequence:
    • MDLSGVKKKS LLGVKENNKK SSTRAPSPTK RKDRSDEKSK DRSKDKGATK ESSEKDRGRD 
KTRKRRSASS GSSSTRSRSS STSSSGSSTS TGSSSGSSSS SASSRSGSSS TSRSSSSSSS 
SGSPSPSRRR HDNRRRSRSK SKPPKRDEKE RKRRSPSPKP TKVHIGRLTR NVTKDHIMEI 
FSTYGKIKMI DMPVERMHPH LSKGYAYVEF ENPDEAEKAL KHMDGGQIDG QEITATAVLA 
PWPRPPPRRF SPPRRMLPPP PMWRRSPPRM RRRSRSPRRR SPVRRRSRSP GRRRHRSRSS 
SNSSR

Genular Protein ID: 828910968

Symbol: H3BMS0_HUMAN

Name: N/A

UniProtKB Accession Codes:

H3BMS0

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 257
  • Mass: 27431
  • Checksum: B26B399DE0BC3751
  • Sequence:
    • MAPSPTKRKD RSDEKSKDRS KDKGATKESS EKDRGRDKTR KRRSASSGSS STRSRSSSTS 
SSGSSTSTGS SSGSSSSSAS SRSGSSSTSR SSSSSSSSGS PSPSRRRHDN RRRSRSKSKP 
PKRDEKERKR RSPSPKPTKV HIGRLTRNVT KDHIMEIFST YGKIKMIDMP VERMHPHLSK 
GYAYVEFENP DEAEKALKHM DGGPAPRGAG PPCAGDHGPR AAAATGAAPA PTPPDKQATE 
ALAPVTYTPP SSVLSLF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.