Details for: UGT2A1

Gene ID: 10941

Symbol: UGT2A1

Ensembl ID: ENSG00000173610

Description: UDP glucuronosyltransferase family 2 member A1 complex locus

Associated with

Other Information

Genular Protein ID: 1343536481

Symbol: UD2A1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10359671

Title: Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase.

PubMed ID: 10359671

DOI: 10.1042/bj3400837

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18719240

Title: The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

PubMed ID: 18719240

DOI: 10.1124/dmd.108.022731

PubMed ID: 19858781

Title: Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.

PubMed ID: 19858781

DOI: 10.1097/fpc.0b013e3283330767

PubMed ID: 19022937

Title: UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly.

PubMed ID: 19022937

DOI: 10.1124/dmd.108.024844

PubMed ID: 23756265

Title: The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation.

PubMed ID: 23756265

DOI: 10.1124/dmd.113.052613

PubMed ID: 23288867

Title: Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.

PubMed ID: 23288867

DOI: 10.1124/dmd.112.049072

PubMed ID: 26220143

Title: Glucuronidation of estrone and 16alpha-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7.

PubMed ID: 26220143

DOI: 10.1016/j.jsbmb.2015.07.013

Sequence Information:

  • Length: 527
  • Mass: 59963
  • Checksum: CFC20162D2AEBBB6
  • Sequence:
  • MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 
    ITPTSNPSLT FEIYKVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 
    VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 
    KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALGG 
    LLLCCPGWSA VADLGSLQPL LPGFKRFSRL SLHCSWDYRL PAGRPTTLCE TMGKAEIWLI 
    RTYWDFEFPR PYLPNFEFVG GLHCKPAKPL PKVLWRYKGK KPATLGNNTQ LFDWIPQNDL 
    LGHPKTKAFI THGGTNGIYE AIYHGVPMVG VPMFADQPDN IAHMKAKGAA VEVNLNTMTS 
    VDLLSALRTV INEPSYKENA MRLSRIHHDQ PVKPLDRAVF WIEFVMRHKG AKHLRVAAHD 
    LTWFQYHSLD VIGFLLVCVT TAIFLVIQCC LFSCQKFGKI GKKKKRE

Genular Protein ID: 3330626758

Symbol: D6RFW5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 483
  • Mass: 55179
  • Checksum: F3B3E51D23530FA2
  • Sequence:
  • MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 
    ITPTSNPSLT FEIYKVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 
    VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 
    KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALGR 
    PTTLCETMGK AEIWLIRTYW DFEFPRPYLP NFEFVGGLHC KPAKPLPKVL WRYKGKKPAT 
    LGNNTQLFDW IPQNDLLGHP KTKAFITHGG TNGIYEAIYH GVPMVGVPMF ADQPDNIAHM 
    KAKGAAVEVN LNTMTSVDLL SALRTVINEP SYKENAMRLS RIHHDQPVKP LDRAVFWIEF 
    VMRHKGAKHL RVAAHDLTWF QYHSLDVIGF LLVCVTTAIF LVIQCCLFSC QKFGKIGKKK 
    KRE

Genular Protein ID: 4051074417

Symbol: A0A140T9Z0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 693
  • Mass: 79063
  • Checksum: 99A2A6FABC31A089
  • Sequence:
  • MLNNLLLFSL QISLIGTTLG GNVLIWPMEG SHWLNVKIII DELIKKEHNV TVLVASGALF 
    ITPTSNPSLT FEIYKVPFGK ERIEGVIKDF VLTWLENRPS PSTIWRFYQE MAKVIKDFHM 
    VSQEICDGVL KNQQLMAKLK KSKFEVLVSD PVFPCGDIVA LKLGIPFMYS LRFSPASTVE 
    KHCGKVPYPP SYVPAVLSEL TDQMSFTDRI RNFISYHLQD YMFETLWKSW DSYYSKALDG 
    SHWLNIKIIL EELIQRNHNV TVLASSATLF INSNPDSPVN FEVIPVSYKK SNIDSLIEHM 
    IMLWIDHRPT PLTIWAFYKE LGKLLDTFFQ INIQLCDGVL KNPKLMARLQ KGGFDVLVAD 
    PVTICGDLVA LKLGIPFMYT LRFSPASTVE RHCGKIPAPV SYVPAALSEL TDQMTFGERI 
    KNTISYSLQD YIFQSYWGEW NSYYSKILGR PTTLCETMGK AEIWLIRTYW DFEFPRPYLP 
    NFEFVGGLHC KPAKPLPKVL WRYKGKKPAT LGNNTQLFDW IPQNDLLGHP KTKAFITHGG 
    TNGIYEAIYH GVPMVGVPMF ADQPDNIAHM KAKGAAVEVN LNTMTSVDLL SALRTVINEP 
    SYKENAMRLS RIHHDQPVKP LDRAVFWIEF VMRHKGAKHL RVAAHDLTWF QYHSLDVIGF 
    LLVCVTTAIF LVIQCCLFSC QKFGKIGKKK KRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.