Details for: MSL3

Gene ID: 10943

Symbol: MSL3

Ensembl ID: ENSG00000005302

Description: MSL complex subunit 3

Associated with

Other Information

Genular Protein ID: 4254236861

Symbol: MS3L1_HUMAN

Name: Male-specific lethal 3 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10395802

Title: Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3.

PubMed ID: 10395802

DOI: 10.1006/geno.1999.5844

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16227571

Title: A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.

PubMed ID: 16227571

DOI: 10.1128/mcb.25.21.9175-9188.2005

PubMed ID: 16543150

Title: Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila.

PubMed ID: 16543150

DOI: 10.1016/j.molcel.2006.02.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20018852

Title: Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.

PubMed ID: 20018852

DOI: 10.1074/jbc.c109.087981

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22547026

Title: Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex.

PubMed ID: 22547026

DOI: 10.1038/cr.2012.72

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 20657587

Title: Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.

PubMed ID: 20657587

DOI: 10.1038/nsmb.1856

PubMed ID: 20943666

Title: Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono- or dimethyllysine 20 on histone H4.

PubMed ID: 20943666

DOI: 10.1074/jbc.m110.134312

PubMed ID: 21217699

Title: Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1.

PubMed ID: 21217699

DOI: 10.1038/nsmb.1960

PubMed ID: 30224647

Title: De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation.

PubMed ID: 30224647

DOI: 10.1038/s41588-018-0220-y

Sequence Information:

  • Length: 521
  • Mass: 59824
  • Checksum: 6DFFB9E183D0CFB9
  • Sequence:
  • MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP EYLIHFNGWN 
    RSWDRWAAED HVLRDTDENR RLQRKLARKA VARLRSTGRK KKRCRLPGVD SVLKGLPTEE 
    KDENDENSLS SSSDCSENKD EEISEESDIE EKTEVKEEPE LQTRREMEER TITIEIPEVL 
    KKQLEDDCYY INRRKRLVKL PCQTNIITIL ESYVKHFAIN AAFSANERPR HHHVMPHANM 
    NVHYIPAEKN VDLCKEMVDG LRITFDYTLP LVLLYPYEQA QYKKVTSSKF FLPIKESATS 
    TNRSQEELSP SPPLLNPSTP QSTESQPTTG EPATPKRRKA EPEALQSLRR STRHSANCDR 
    LSESSASPQP KRRQQDTSAS MPKLFLHLEK KTPVHSRSSS PIPLTPSKEG SAVFAGFEGR 
    RTNEINEVLS WKLVPDNYPP GDQPPPPSYI YGAQHLLRLF VKLPEILGKM SFSEKNLKAL 
    LKHFDLFLRF LAEYHDDFFP ESAYVAACEA HYSTKNPRAI Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.