KDELR1 | ENSG00000105438 | NCBI 10945

Details for: KDELR1

Gene ID: 10945

Symbol: KDELR1

Ensembl ID: ENSG00000105438

Description: KDEL endoplasmic reticulum protein retention receptor 1

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Copi-dependent golgi-to-er retrograde traffic
(R-HSA-6811434)
Copi-mediated anterograde transport
(R-HSA-6807878)
Er to golgi anterograde transport
(R-HSA-199977)
Golgi-to-er retrograde transport
(R-HSA-8856688)
Intra-golgi and retrograde golgi-to-er traffic
(R-HSA-6811442)
Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Cis-golgi network
(GO:0005801)
Copi-coated vesicle membrane
(GO:0030663)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum-golgi intermediate compartment
(GO:0005793)
Endoplasmic reticulum-golgi intermediate compartment membrane
(GO:0033116)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum to golgi vesicle-mediated transport
(GO:0006888)
Er retention sequence binding
(GO:0046923)
Golgi membrane
(GO:0000139)
Kdel sequence binding
(GO:0005046)
Protein binding
(GO:0005515)
Protein retention in er lumen
(GO:0006621)
Protein transport
(GO:0015031)
Retrograde vesicle-mediated transport, golgi to endoplasmic reticulum
(GO:0006890)
T cell apoptotic process
(GO:0070231)
T cell differentiation
(GO:0030217)
Transport vesicle
(GO:0030133)

Other Information

Proteins

ER lumen protein-retaining receptor 1

Genular Protein ID: 1331031125

Symbol: ERD21_HUMAN

Name: ER lumen protein-retaining receptor 1

UniProtKB Accession Codes:

P24390 B2R6N4 Q54A39 Q8NBW7

Database IDs:

Citations:

PubMed ID: 2172835

Title: A human homologue of the yeast HDEL receptor.

PubMed ID: 2172835

DOI: 10.1038/348162a0

PubMed ID: 12761501

Title: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

PubMed ID: 12761501

DOI: 10.1038/sj.onc.1206406

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8392934

Title: Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

PubMed ID: 8392934

DOI: 10.1002/j.1460-2075.1993.tb05943.x

PubMed ID: 11703931

Title: KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET.

PubMed ID: 11703931

DOI: 10.1016/s1534-5807(01)00004-1

PubMed ID: 14517323

Title: The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus.

PubMed ID: 14517323

DOI: 10.1091/mbc.e03-04-0194

PubMed ID: 18086916

Title: A molecular specificity code for the three mammalian KDEL receptors.

PubMed ID: 18086916

DOI: 10.1083/jcb.200705180

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30846601

Title: Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.

PubMed ID: 30846601

DOI: 10.1126/science.aaw2859

Sequence Information:

Length: 212
Mass: 24542
Checksum: B863C0F09CFC0551
Sequence:

MNLFRFLGDL SHLLAIILLL LKIWKSRSCA GISGKSQVLF AVVFTARYLD LFTNYISLYN 
TCMKVVYIAC SFTTVWLIYS KFKATYDGNH DTFRVEFLVV PTAILAFLVN HDFTPLEILW 
TFSIYLESVA ILPQLFMVSK TGEAETITSH YLFALGVYRT LYLFNWIWRY HFEGFFDLIA 
IVAGLVQTVL YCDFFYLYIT KVLKGKKLSL PA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: KDELR1

Associated with

Other Information

A human homologue of the yeast HDEL receptor. PubMed ID: 2172835

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. PubMed ID: 12761501

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport. PubMed ID: 8392934

KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET. PubMed ID: 11703931

The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus. PubMed ID: 14517323

A molecular specificity code for the three mammalian KDEL receptors. PubMed ID: 18086916

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor. PubMed ID: 30846601