Details for: SF3A3

Gene ID: 10946

Symbol: SF3A3

Ensembl ID: ENSG00000183431

Description: splicing factor 3a subunit 3

Associated with

Other Information

Genular Protein ID: 2818186516

Symbol: SF3A3_HUMAN

Name: Splicing factor 3A subunit 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8022796

Title: Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114.

PubMed ID: 8022796

DOI: 10.1073/pnas.91.14.6403

PubMed ID: 7816610

Title: Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.

PubMed ID: 7816610

DOI: 10.1093/nar/22.24.5223

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10882114

Title: Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.

PubMed ID: 10882114

DOI: 10.1016/s1097-2765(00)80318-4

PubMed ID: 11533230

Title: Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.

PubMed ID: 11533230

DOI: 10.1128/mcb.21.19.6406-6417.2001

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21349847

Title: Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.

PubMed ID: 21349847

DOI: 10.1074/jbc.m110.201491

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17098193

Title: Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP.

PubMed ID: 17098193

DOI: 10.1016/j.str.2006.09.009

PubMed ID: 29360106

Title: Structure of the human activated spliceosome in three conformational states.

PubMed ID: 29360106

DOI: 10.1038/cr.2018.14

PubMed ID: 30315277

Title: Structures of the human pre-catalytic spliceosome and its precursor spliceosome.

PubMed ID: 30315277

DOI: 10.1038/s41422-018-0094-7

PubMed ID: 32494006

Title: Molecular architecture of the human 17S U2 snRNP.

PubMed ID: 32494006

DOI: 10.1038/s41586-020-2344-3

PubMed ID: 34822310

Title: Structural basis of branch site recognition by the human spliceosome.

PubMed ID: 34822310

DOI: 10.1126/science.abm4245

PubMed ID: 36797247

Title: Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.

PubMed ID: 36797247

DOI: 10.1038/s41467-023-36489-x

Sequence Information:

  • Length: 501
  • Mass: 58849
  • Checksum: 6E6F6EA17777E1E2
  • Sequence:
  • METILEQQRR YHEEKERLMD VMAKEMLTKK STLRDQINSD HRTRAMQDRY MEVSGNLRDL 
    YDDKDGLRKE ELNAISGPNE FAEFYNRLKQ IKEFHRKHPN EICVPMSVEF EELLKARENP 
    SEEAQNLVEF TDEEGYGRYL DLHDCYLKYI NLKASEKLDY ITYLSIFDQL FDIPKERKNA 
    EYKRYLEMLL EYLQDYTDRV KPLQDQNELF GKIQAEFEKK WENGTFPGWP KETSSALTHA 
    GAHLDLSAFS SWEELASLGL DRLKSALLAL GLKCGGTLEE RAQRLFSTKG KSLESLDTSL 
    FAKNPKSKGT KRDTERNKDI AFLEAQIYEY VEILGEQRHL THENVQRKQA RTGEEREEEE 
    EEQISESESE DEENEIIYNP KNLPLGWDGK PIPYWLYKLH GLNINYNCEI CGNYTYRGPK 
    AFQRHFAEWR HAHGMRCLGI PNTAHFANVT QIEDAVSLWA KLKLQKASER WQPDTEEEYE 
    DSSGNVVNKK TYEDLKRQGL L

Genular Protein ID: 1152352684

Symbol: B4DW90_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 448
  • Mass: 52428
  • Checksum: F8734FA03680CFAD
  • Sequence:
  • METILEQQRR YHEEKERLMD VMAKEMLTKK STLRDQINSD HRTRAMQDIC VPMSVEFEEL 
    LKARENPSEE AQNLVEFTDE EGYGRYLDLH DCYLKYINLK ASEKLDYITY LSIFDQLFDI 
    PKERKNAEYK RYLEMLLEYL QDYTDRVKPL QDQNELFGKI QAEFEKKWEN GTFPGWPKET 
    SSALTHAGAH LDLSAFSSWE ELASLGLDRL KSALLALGLK CGGTLEERAQ RLFSTKGKSL 
    ESLDTSLFAK SPKSKGTKRD TERNKDIAFL EAQIYEYVEI LGEQRHLTHE NVQRKQARTG 
    EEREEEEEEQ ISESESEDEE NEIIYNPKNL PLGWDGKPIP YWLYKLHGLN INYNCEICGN 
    YTYRGPKAFQ RHFAEWRHAH GMRCLGIPNT AHFANVTQIE DAVSLWAKLK LQKASERWQP 
    DTEEEYEDSS GNVVNKKTYE DLKRQGLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.