Details for: STARD3

Gene ID: 10948

Symbol: STARD3

Ensembl ID: ENSG00000131748

Description: StAR related lipid transfer domain containing 3

Associated with

Other Information

Genular Protein ID: 1957222103

Symbol: STAR3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7490069

Title: Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.

PubMed ID: 7490069

DOI: 10.1006/geno.1995.1163

PubMed ID: 9270027

Title: Isolation of a candidate gene, CAB1, for cholesterol transport to mitochondria from the c-ERBB-2 amplicon by a modified cDNA selection method.

PubMed ID: 9270027

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11053434

Title: The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.

PubMed ID: 11053434

DOI: 10.1074/jbc.m006279200

PubMed ID: 12070139

Title: MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondria.

PubMed ID: 12070139

DOI: 10.1074/jbc.m200003200

PubMed ID: 15718238

Title: Functional characterization of the MENTAL domain.

PubMed ID: 15718238

DOI: 10.1074/jbc.m500723200

PubMed ID: 15930133

Title: MLN64 is involved in actin-mediated dynamics of late endocytic organelles.

PubMed ID: 15930133

DOI: 10.1091/mbc.e04-12-1105

PubMed ID: 16709157

Title: MLN64 and MENTHO, two mediators of endosomal cholesterol transport.

PubMed ID: 16709157

DOI: 10.1042/bst0340343

PubMed ID: 16990645

Title: Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol.

PubMed ID: 16990645

DOI: 10.1194/jlr.m600232-jlr200

PubMed ID: 19965586

Title: MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein.

PubMed ID: 19965586

DOI: 10.1194/jlr.m002345

PubMed ID: 21322544

Title: Identification of StARD3 as a lutein-binding protein in the macula of the primate retina.

PubMed ID: 21322544

DOI: 10.1021/bi101906y

PubMed ID: 22514632

Title: MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site.

PubMed ID: 22514632

DOI: 10.1371/journal.pone.0034424

PubMed ID: 24105263

Title: STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

PubMed ID: 24105263

DOI: 10.1242/jcs.139295

PubMed ID: 27679500

Title: The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64), in BRIN-BD11 insulinoma cells.

PubMed ID: 27679500

DOI: 10.1007/s13238-016-0315-0

PubMed ID: 28377464

Title: STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites.

PubMed ID: 28377464

DOI: 10.15252/embj.201695917

PubMed ID: 29858488

Title: Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

PubMed ID: 29858488

DOI: 10.15252/embr.201745453

PubMed ID: 10802740

Title: Structure and lipid transport mechanism of a StAR-related domain.

PubMed ID: 10802740

DOI: 10.1038/75192

PubMed ID: 27487925

Title: Structure of the lutein-binding domain of human StARD3 at 1.74A resolution and model of a complex with lutein.

PubMed ID: 27487925

DOI: 10.1107/s2053230x16010694

PubMed ID: 33124732

Title: FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

PubMed ID: 33124732

DOI: 10.15252/embj.2019104369

Sequence Information:

  • Length: 445
  • Mass: 50502
  • Checksum: 8EBFBAF013CFDC7E
  • Sequence:
  • MSKLPRELTR DLERSLPAVA SLGSSLSHSQ SLSSHLLPPP EKRRAISDVR RTFCLFVTFD 
    LLFISLLWII ELNTNTGIRK NLEQEIIQYN FKTSFFDIFV LAFFRFSGLL LGYAVLRLRH 
    WWVIAVTTLV SSAFLIVKVI LSELLSKGAF GYLLPIVSFV LAWLETWFLD FKVLPQEAEE 
    ERWYLAAQVA VARGPLLFSG ALSEGQFYSP PESFAGSDNE SDEEVAGKKS FSAQEREYIR 
    QGKEATAVVD QILAQEENWK FEKNNEYGDT VYTIEVPFHG KTFILKTFLP CPAELVYQEV 
    ILQPERMVLW NKTVTACQIL QRVEDNTLIS YDVSAGAAGG VVSPRDFVNV RRIERRRDRY 
    LSSGIATSHS AKPPTHKYVR GENGPGGFIV LKSASNPRVC TFVWILNTDL KGRLPRYLIH 
    QSLAATMFEF AFHLRQRISE LGARA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.