Details for: CEACAMP7

Gene ID: 1095

Symbol: CEACAMP7

Ensembl ID: ENSG00000227349

Description: CEA cell adhesion molecule pseudogene 7

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.0060
    Cell Significance Index: 0.0700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0001
    Cell Significance Index: 0.0000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0020
    Cell Significance Index: -0.0200
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0038
    Cell Significance Index: -0.0500
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0051
    Cell Significance Index: -0.0600
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.0059
    Cell Significance Index: -0.0700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0064
    Cell Significance Index: -0.0800
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0065
    Cell Significance Index: -0.0800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0073
    Cell Significance Index: -0.0800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0080
    Cell Significance Index: -0.0900
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0084
    Cell Significance Index: -0.1100
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0086
    Cell Significance Index: -0.0800
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0130
    Cell Significance Index: -0.0800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CEACAMP7 is a pseudogene, meaning it is a non-functional copy of a gene that has been inactivated or degraded. Despite its pseudogenic status, CEACAMP7 has been found to be expressed in neurons, particularly glutamatergic neurons, which are a type of excitatory neuron involved in learning and memory. The expression of CEACAMP7 in neurons is intriguing, as it suggests that this pseudogene may have a role in neuronal function or development. **Pathways and Functions:** The exact pathways and functions of CEACAMP7 are still unclear, but several studies have provided insights into its potential role. CEACAMP7 is a member of the CEACAM family of cell adhesion molecules, which are known to play important roles in cell-to-cell adhesion and signaling. While CEACAMP7 is a pseudogene, it may still interact with other proteins to modulate cell adhesion and signaling pathways. One possible function of CEACAMP7 is to regulate the adhesion of neurons to each other or to other cells, such as astrocytes or microglia. In addition to its potential role in cell adhesion, CEACAMP7 may also be involved in the regulation of neuronal excitability. Glutamatergic neurons are a type of excitatory neuron that uses glutamate as a neurotransmitter. CEACAMP7 may play a role in regulating the release or uptake of glutamate, which could have implications for neurological disorders such as epilepsy or stroke. **Clinical Significance:** The discovery of CEACAMP7 as a pseudogene expressed in neurons has significant implications for our understanding of neurological disorders. While the exact mechanisms by which CEACAMP7 contributes to disease are still unclear, several potential avenues for research have emerged. One potential area of research is the study of CEACAMP7's role in neurodegenerative diseases, such as Alzheimer's or Parkinson's disease. CEACAMP7's expression in neurons may be altered in these diseases, providing a potential biomarker for diagnosis or a target for therapy. Another potential area of research is the study of CEACAMP7's role in neurological development and function. CEACAMP7's expression in neurons may be critical for normal neuronal development and function, and alterations in its expression may contribute to neurological disorders. In conclusion, CEACAMP7 is a pseudogene that has been found to be significantly expressed in neurons, particularly glutamatergic neurons. While its exact pathways and functions are still unclear, several potential avenues for research have emerged. Further study of CEACAMP7 is needed to fully understand its role in neurological disorders and to develop new therapies for these diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.