Details for: CBX1

Gene ID: 10951

Symbol: CBX1

Ensembl ID: ENSG00000108468

Description: chromobox 1

Associated with

Other Information

Genular Protein ID: 4089657506

Symbol: CBX1_HUMAN

Name: Chromobox protein homolog 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9169582

Title: Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis.

PubMed ID: 9169582

DOI: 10.1007/s004120050219

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10460410

Title: Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells.

PubMed ID: 10460410

DOI: 10.1007/s004120050372

PubMed ID: 10202156

Title: Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.

PubMed ID: 10202156

DOI: 10.1093/emboj/18.7.1923

PubMed ID: 14651845

Title: EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.

PubMed ID: 14651845

DOI: 10.1016/s0092-8674(03)00930-9

PubMed ID: 15947784

Title: Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69.

PubMed ID: 15947784

DOI: 10.1038/sj.embor.7400415

PubMed ID: 15899859

Title: In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation.

PubMed ID: 15899859

DOI: 10.1128/mcb.25.11.4552-4564.2005

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 20850016

Title: Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

PubMed ID: 20850016

DOI: 10.1016/j.cell.2010.08.020

PubMed ID: 19880879

Title: ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1.

PubMed ID: 19880879

DOI: 10.1074/jbc.m109.065862

PubMed ID: 25750265

Title: Retraction: 'ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1'.

PubMed ID: 25750265

DOI: 10.1074/jbc.a109.065862

PubMed ID: 20562864

Title: Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

PubMed ID: 20562864

DOI: 10.1038/ncb2075

PubMed ID: 20498703

Title: Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10.

PubMed ID: 20498703

DOI: 10.1371/journal.pone.0010620

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23542155

Title: Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway.

PubMed ID: 23542155

DOI: 10.1038/nsmb.2532

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 26721387

Title: Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.

PubMed ID: 26721387

DOI: 10.1093/nar/gkv1526

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28977666

Title: CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

PubMed ID: 28977666

DOI: 10.1093/nar/gkx711

PubMed ID: 16615912

Title: Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.

PubMed ID: 16615912

DOI: 10.1016/j.str.2006.01.007

PubMed ID: 21346195

Title: Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.

PubMed ID: 21346195

DOI: 10.1091/mbc.e11-01-0009

Sequence Information:

  • Length: 185
  • Mass: 21418
  • Checksum: BE687AF9C66E48E3
  • Sequence:
  • MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN TWEPEENLDC 
    PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP RGFARGLEPE 
    RIIGATDSSG ELMFLMKWKN SDEADLVPAK EANVKCPQVV ISFYEERLTW HSYPSEDDDK 
    KDDKN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.