Details for: CEACAMP9

Gene ID: 1097

Symbol: CEACAMP9

Ensembl ID: ENSG00000230529

Description: CEA cell adhesion molecule pseudogene 9

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0017
    Cell Significance Index: -0.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CEACAMP9 is a pseudogene, which means it is a non-functional copy of a gene that has undergone mutations or other alterations, rendering it incapable of producing a protein. Despite its pseudogenic status, CEACAMP9 is significantly expressed in stromal cells and neurons, suggesting a potential role in these cell types. The expression of CEACAMP9 in these cells is intriguing, as it may indicate involvement in cell-cell interactions, adhesion, or signaling pathways. **Pathways and Functions:** The exact pathways and functions of CEACAMP9 are not well understood, as it is a pseudogene. However, its expression in stromal cells and neurons suggests that it may be involved in cell-cell interactions, adhesion, or signaling pathways. CEACAM9, its functional counterpart, has been implicated in various cellular processes, including cell adhesion, migration, and immune responses. Although CEACAMP9 is a pseudogene, it is possible that it may interact with CEACAM9 or other molecules to modulate these processes. One potential pathway of interest is the Notch signaling pathway, which is crucial for cell fate determination, differentiation, and proliferation. CEACAM9 has been shown to interact with Notch receptors, suggesting that CEACAMP9 may also interact with this pathway. Further studies are necessary to determine the specific mechanisms by which CEACAMP9 influences cellular processes. **Clinical Significance:** Despite its pseudogenic status, CEACAMP9 has potential implications for various diseases, particularly those affecting the nervous system and immune system. The expression of CEACAMP9 in neurons suggests that it may play a role in neurodegenerative diseases, such as Alzheimer's or Parkinson's, where cell-cell interactions and signaling pathways are disrupted. Furthermore, CEACAMP9's expression in stromal cells implies that it may be involved in immune responses, potentially modulating the activity of immune cells or influencing the development of autoimmune diseases. Further research is needed to determine the specific mechanisms by which CEACAMP9 influences these processes. In conclusion, CEACAMP9, a pseudogene of the cell adhesion molecule CEACAM9, is a gene with significant expression in stromal cells and neurons. While its exact pathways and functions are not well understood, its potential implications for various diseases, particularly those affecting the nervous system and immune system, make it a gene of interest for further investigation. Further studies are necessary to determine the specific mechanisms by which CEACAMP9 influences cellular processes and to explore its potential therapeutic applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.