Details for: ASCC3

Gene ID: 10973

Symbol: ASCC3

Ensembl ID: ENSG00000112249

Description: activating signal cointegrator 1 complex subunit 3

Associated with

Other Information

Genular Protein ID: 1058257806

Symbol: ASCC3_HUMAN

Name: Activating signal cointegrator 1 complex subunit 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12077347

Title: Novel transcription coactivator complex containing activating signal cointegrator 1.

PubMed ID: 12077347

DOI: 10.1128/mcb.22.14.5203-5211.2002

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22055184

Title: DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.

PubMed ID: 22055184

DOI: 10.1016/j.molcel.2011.08.039

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29144457

Title: A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.

PubMed ID: 29144457

DOI: 10.1038/nature24484

PubMed ID: 28757607

Title: Ubiquitination of stalled ribosome triggers ribosome-associated quality control.

PubMed ID: 28757607

DOI: 10.1038/s41467-017-00188-1

PubMed ID: 29997253

Title: RNA ligase-like domain in activating signal cointegrator 1 complex subunit 1 (ASCC1) regulates ASCC complex function during alkylation damage.

PubMed ID: 29997253

DOI: 10.1074/jbc.ra117.000114

PubMed ID: 31799605

Title: The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.

PubMed ID: 31799605

DOI: 10.1093/nar/gkz1147

PubMed ID: 32579943

Title: The ASC-1 complex disassembles collided ribosomes.

PubMed ID: 32579943

DOI: 10.1016/j.molcel.2020.06.006

PubMed ID: 32099016

Title: Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.

PubMed ID: 32099016

DOI: 10.1038/s41598-020-60241-w

PubMed ID: 36302773

Title: A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.

PubMed ID: 36302773

DOI: 10.1038/s41467-022-34097-9

Sequence Information:

  • Length: 2202
  • Mass: 251460
  • Checksum: 9F074E6E5853399C
  • Sequence:
  • MALPRLTGAL RSFSNVTKQD NYNEEVADLK IKRSKLHEQV LDLGLTWKKI IKFLNEKLEK 
    SKMQSINEDL KDILHAAKQI VGTDNGREAI ESGAAFLFMT FHLKDSVGHK ETKAIKQMFG 
    PFPSSSATAA CNATNRIISH FSQDDLTALV QMTEKEHGDR VFFGKNLAFS FDMHDLDHFD 
    ELPINGETQK TISLDYKKFL NEHLQEACTP ELKPVEKTNG SFLWCEVEKY LNSTLKEMTE 
    VPRVEDLCCT LYDMLASIKS GDELQDELFE LLGPEGLELI EKLLQNRITI VDRFLNSSND 
    HRFQALQDNC KKILGENAKP NYGCQVTIQS EQEKQLMKQY RREEKRIARR EKKAGEDLEV 
    SEGLMCFDPK ELRIQREQAL LNARSVPILS RQRDADVEKI HYPHVYDSQA EAMKTSAFIA 
    GAKMILPEGI QRENNKLYEE VRIPYSEPMP LSFEEKPVYI QDLDEIGQLA FKGMKRLNRI 
    QSIVFETAYN TNENMLICAP TGAGKTNIAM LTVLHEIRQH FQQGVIKKNE FKIVYVAPMK 
    ALAAEMTDYF SRRLEPLGII VKELTGDMQL SKSEILRTQM LVTTPEKWDV VTRKSVGDVA 
    LSQIVRLLIL DEVHLLHEDR GPVLESIVAR TLRQVESTQS MIRILGLSAT LPNYLDVATF 
    LHVNPYIGLF FFDGRFRPVP LGQTFLGIKC ANKMQQLNNM DEVCYENVLK QVKAGHQVMV 
    FVHARNATVR TAMSLIERAK NCGHIPFFFP TQGHDYVLAE KQVQRSRNKQ VRELFPDGFS 
    IHHAGMLRQD RNLVENLFSN GHIKVLVCTA TLAWGVNLPA HAVIIKGTQI YAAKRGSFVD 
    LGILDVMQIF GRAGRPQFDK FGEGIIITTH DKLSHYLTLL TQRNPIESQF LESLADNLNA 
    EIALGTVTNV EEAVKWISYT YLYVRMRANP LAYGISHKAY QIDPTLRKHR EQLVIEVGRK 
    LDKAQMIRFE ERTGYFSSTD LGRTASHYYI KYNTIETFNE LFDAHKTEGD IFAIVSKAEE 
    FDQIKVREEE IEELDTLLSN FCELSTPGGV ENSYGKINIL LQTYISRGEM DSFSLISDSA 
    YVAQNAARIV RALFEIALRK RWPTMTYRLL NLSKVIDKRL WGWASPLRQF SILPPHILTR 
    LEEKKLTVDK LKDMRKDEIG HILHHVNIGL KVKQCVHQIP SVMMEASIQP ITRTVLRVTL 
    SIYADFTWND QVHGTVGEPW WIWVEDPTND HIYHSEYFLA LKKQVISKEA QLLVFTIPIF 
    EPLPSQYYIR AVSDRWLGAE AVCIINFQHL ILPERHPPHT ELLDLQPLPI TALGCKAYEA 
    LYNFSHFNPV QTQIFHTLYH TDCNVLLGAP TGSGKTVAAE LAIFRVFNKY PTSKAVYIAP 
    LKALVRERMD DWKVRIEEKL GKKVIELTGD VTPDMKSIAK ADLIVTTPEK WDGVSRSWQN 
    RNYVQQVTIL IIDEIHLLGE ERGPVLEVIV SRTNFISSHT EKPVRIVGLS TALANARDLA 
    DWLNIKQMGL FNFRPSVRPV PLEVHIQGFP GQHYCPRMAS MNKPAFQAIR SHSPAKPVLI 
    FVSSRRQTRL TALELIAFLA TEEDPKQWLN MDEREMENII ATVRDSNLKL TLAFGIGMHH 
    AGLHERDRKT VEELFVNCKV QVLIATSTLA WGVNFPAHLV IIKGTEYYDG KTRRYVDFPI 
    TDVLQMMGRA GRPQFDDQGK AVILVHDIKK DFYKKFLYEP FPVESSLLGV LSDHLNAEIA 
    GGTITSKQDA LDYITWTYFF RRLIMNPSYY NLGDVSHDSV NKFLSHLIEK SLIELELSYC 
    IEIGEDNRSI EPLTYGRIAS YYYLKHQTVK MFKDRLKPEC STEELLSILS DAEEYTDLPV 
    RHNEDHMNSE LAKCLPIESN PHSFDSPHTK AHLLLQAHLS RAMLPCPDYD TDTKTVLDQA 
    LRVCQAMLDV AANQGWLVTV LNITNLIQMV IQGRWLKDSS LLTLPNIENH HLHLFKKWKP 
    IMKGPHARGR TSIESLPELI HACGGKDHVF SSMVESELHA AKTKQAWNFL SHLPVINVGI 
    SVKGSWDDLV EGHNELSVST LTADKRDDNK WIKLHADQEY VLQVSLQRVH FGFHKGKPES 
    CAVTPRFPKS KDEGWFLILG EVDKRELIAL KRVGYIRNHH VASLSFYTPE IPGRYIYTLY 
    FMSDCYLGLD QQYDIYLNVT QASLSAQVNT KVSDSLTDLA LK

Genular Protein ID: 983557120

Symbol: B4DR60_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1041
  • Mass: 119066
  • Checksum: 4B1A50580B968ED1
  • Sequence:
  • MTFHLKDSVG HKETKAIKQM FGPFPSSSAT AACNATNRII SHFSQDDFTA LVQMTEKEHG 
    DRVFFGKNLA FSFDMHDLDH FDELPINGET QKTISLDYKK FLNEHLQEAC TPELKPVEKT 
    NGSFLWCEVE KYLNSTLKEM TEVPRVEDLC CTLYDMLASI KSGDELQDEL FELLGPEGLE 
    LIEKLLQNRI TIVDRFLNSS NDHRFQALQD NCKKILGENA KPNYGCQVTI QSEQEKQLMK 
    QYRREEKRIA RREKKAGEDL EVSEGLMCFD PKELRIQREQ ALLNARSVPI LSRQRDADVE 
    KIHYPHVYDS QAEAMKTSAF IAGAKMILPE GIQRENNKLY EEVRIPYSEP MPLSFEEKPV 
    YIQDLDEIGQ LAFKGMKRLN RIQSIVFETA YNTNENMLIC APTGAGKTNI AMLTVLHEIR 
    QHFQQGVIKK NEFKIVYVAP MKALAAEMTD YFSRRLEPLG IIVKELTGDM QLSKSEILRT 
    QMLVTTPEKW DVVTRKSVGD VALSQIVRLL ILDEVHLLHE DRGPVLESIV ARTLRQVEST 
    QSMIRILGLS ATLPNYLDVA TFLHVNPYIG LFFFDGRFRP VPLGQTFLGI KCANKMQQLN 
    NMDEVCYENV LKQVKAGHQV MVFVHARNAT VRTAMSLIER AKNCGHIPFF FPTQGHDYVL 
    AEKQVQRSRN KQVRELFPDG FSIHHAGMLR QDRNLVENLF SNGHIKVLVC TATLAWGVNL 
    PAHAVIIKGT QIYAAKRGSF VDLGILDVMQ IFGRAGRPQF DKFGEGIIIT THDKLSHYLT 
    LLTQRNPIES QFLESLADNL NAEIALGTVT NVEEAVKWIS YTYLYVRMRA NPLAYGISHK 
    AYQIDPTLRK HREQLVIEVG RKLDKAQMIR FEERTGYFSP TDLGRTASHY YIKYNTIETF 
    NELFDAHKTE GDIFAIVSKA EEFDQIKVRE EEIEELDTLL SNFCELSTPG GVENSYGKIN 
    ILLQTYISRG EMDSFSLISD SAYVAQNAAR IVRALFEIAL RKRWPTMTYR LLNLSKVIDK 
    RLWGWASPLR QFSILPPHIL T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.