SLC38A3 | ENSG00000188338 | NCBI 10991

Details for: SLC38A3

Gene ID: 10991

Symbol: SLC38A3

Ensembl ID: ENSG00000188338

Description: solute carrier family 38 member 3

Associated with

Amino acid transport across the plasma membrane
(R-HSA-352230)
Slc-mediated transmembrane transport
(R-HSA-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-HSA-425393)
Transport of small molecules
(R-HSA-382551)
Amino acid transmembrane transport
(GO:0003333)
Amino acid transmembrane transporter activity
(GO:0015171)
Amino acid transport
(GO:0006865)
Apical plasma membrane
(GO:0016324)
Asparagine transport
(GO:0006867)
Basolateral plasma membrane
(GO:0016323)
Cellular response to potassium ion starvation
(GO:0051365)
Female pregnancy
(GO:0007565)
Glutamine secretion
(GO:0010585)
Glutamine transport
(GO:0006868)
Histidine transport
(GO:0015817)
Intracellular amino acid homeostasis
(GO:0080144)
L-alanine transmembrane transporter activity
(GO:0015180)
L-alanine transport
(GO:0015808)
L-asparagine, sodium:proton antiporter activity
(GO:0140831)
L-asparagine import across plasma membrane
(GO:1903811)
L-asparagine transmembrane transporter activity
(GO:0015182)
L-glutamine, sodium:proton antiporter activity
(GO:0140830)
L-glutamine import across plasma membrane
(GO:1903803)
L-glutamine transmembrane transporter activity
(GO:0015186)
L-histidine, sodium:proton antiporter activity
(GO:0140832)
L-histidine import across plasma membrane
(GO:1903810)
L-histidine transmembrane transporter activity
(GO:0005290)
L-histidine transport
(GO:1902024)
Neutral l-amino acid:sodium symporter activity
(GO:0005295)
Plasma membrane
(GO:0005886)
Positive regulation of glutamine transport
(GO:2000487)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Sodium ion transport
(GO:0006814)
Transport across blood-brain barrier
(GO:0150104)

Other Information

Proteins

N-system amino acid transporter 1

Genular Protein ID: 1004986245

Symbol: S38A3_HUMAN

Name: N-system amino acid transporter 1

UniProtKB Accession Codes:

Q99624 B2R8Q0 Q6IB34

Database IDs:

Citations:

PubMed ID: 10823827

Title: Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.

PubMed ID: 10823827

DOI: 10.1074/jbc.m002282200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 34605855

Title: Biallelic variants in SLC38A3 encoding a glutamine transporter cause epileptic encephalopathy.

PubMed ID: 34605855

DOI: 10.1093/brain/awab369

Sequence Information:

Length: 504
Mass: 55773
Checksum: 86E7D205C6001C60
Sequence:

MEAPLQTEMV ELVPNGKHSE GLLPVITPMA GNQRVEDPAR SCMEGKSFLQ KSPSKEPHFT 
DFEGKTSFGM SVFNLSNAIM GSGILGLAYA MANTGIILFL FLLTAVALLS SYSIHLLLKS 
SGVVGIRAYE QLGYRAFGTP GKLAAALAIT LQNIGAMSSY LYIIKSELPL VIQTFLNLEE 
KTSDWYMNGN YLVILVSVTI ILPLALMRQL GYLGYSSGFS LSCMVFFLIA VIYKKFHVPC 
PLPPNFNNTT GNFSHVEIVK EKVQLQVEPE ASAFCTPSYF TLNSQTAYTI PIMAFAFVCH 
PEVLPIYTEL KDPSKKKMQH ISNLSIAVMY IMYFLAALFG YLTFYNGVES ELLHTYSKVD 
PFDVLILCVR VAVLTAVTLT VPIVLFPVRR AIQQMLFPNQ EFSWLRHVLI AVGLLTCINL 
LVIFAPNILG IFGVIGATSA PFLIFIFPAI FYFRIMPTEK EPARSTPKIL ALCFAMLGFL 
LMTMSLSFII IDWASGTSRH GGNH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC38A3

Associated with

Other Information

Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter. PubMed ID: 10823827

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Biallelic variants in SLC38A3 encoding a glutamine transporter cause epileptic encephalopathy. PubMed ID: 34605855