Details for: LILRB4

Gene ID: 11006

Symbol: LILRB4

Ensembl ID: ENSG00000186818

Description: leukocyte immunoglobulin like receptor B4

Associated with

  • Adaptive immune system
    (R-HSA-1280218)
  • Immune system
    (R-HSA-168256)
  • Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
    (R-HSA-198933)
  • Adaptive immune response
    (GO:0002250)
  • Apolipoprotein binding
    (GO:0034185)
  • Cell surface
    (GO:0009986)
  • Cytokine-mediated signaling pathway
    (GO:0019221)
  • Cytoplasmic side of plasma membrane
    (GO:0009898)
  • Extracellular exosome
    (GO:0070062)
  • Fc receptor mediated inhibitory signaling pathway
    (GO:0002774)
  • Fibronectin binding
    (GO:0001968)
  • Inhibitory mhc class i receptor activity
    (GO:0032396)
  • Interleukin-10-mediated signaling pathway
    (GO:0140105)
  • Negative regulation of activated t cell proliferation
    (GO:0046007)
  • Negative regulation of canonical nf-kappab signal transduction
    (GO:0043124)
  • Negative regulation of chemokine production
    (GO:0032682)
  • Negative regulation of cytokine production involved in inflammatory response
    (GO:1900016)
  • Negative regulation of cytotoxic t cell differentiation
    (GO:0045584)
  • Negative regulation of interleukin-1 beta production
    (GO:0032691)
  • Negative regulation of interleukin-2 production
    (GO:0032703)
  • Negative regulation of interleukin-5 production
    (GO:0032714)
  • Negative regulation of interleukin-6 production
    (GO:0032715)
  • Negative regulation of interleukin-10 production
    (GO:0032693)
  • Negative regulation of ip-10 production
    (GO:0071659)
  • Negative regulation of mapk cascade
    (GO:0043409)
  • Negative regulation of mirna transcription
    (GO:1902894)
  • Negative regulation of monocyte activation
    (GO:0150102)
  • Negative regulation of osteoclast differentiation
    (GO:0045671)
  • Negative regulation of protein localization to nucleus
    (GO:1900181)
  • Negative regulation of protein tyrosine kinase activity
    (GO:0061099)
  • Negative regulation of signaling receptor activity
    (GO:2000272)
  • Negative regulation of t cell costimulation
    (GO:2000524)
  • Negative regulation of t cell cytokine production
    (GO:0002725)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Negative regulation of t cell receptor signaling pathway
    (GO:0050860)
  • Negative regulation of tumor necrosis factor production
    (GO:0032720)
  • Negative regulation of type ii interferon production
    (GO:0032689)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of cd8-positive, alpha-beta t cell differentiation
    (GO:0043378)
  • Positive regulation of regulatory t cell differentiation
    (GO:0045591)
  • Positive regulation of t cell anergy
    (GO:0002669)
  • Protein binding
    (GO:0005515)
  • Protein phosphatase binding
    (GO:0019903)
  • Receptor internalization
    (GO:0031623)
  • Signaling receptor inhibitor activity
    (GO:0030547)
  • Tolerance induction
    (GO:0002507)
  • Transmembrane receptor protein tyrosine kinase inhibitor activity
    (GO:0030293)

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 3.6
    Marker Score: 2,183
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 3.19
    Marker Score: 2,254
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 2.02
    Marker Score: 843
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.97
    Marker Score: 1,340
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.74
    Marker Score: 1,745
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 1.65
    Marker Score: 6,845
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.58
    Marker Score: 1,608
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.53
    Marker Score: 85,555
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.47
    Marker Score: 2,870
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 1.24
    Marker Score: 508
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.23
    Marker Score: 611
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.15
    Marker Score: 7,663
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.15
    Marker Score: 1,317
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.09
    Marker Score: 12,641
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.08
    Marker Score: 2,791
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,820
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,044
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,408
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,317
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.92
    Marker Score: 5,603
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,738
  • Cell Name: plasmacytoid dendritic cell, human (CL0001058)
    Fold Change: 0.88
    Marker Score: 231
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,286
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.86
    Marker Score: 1,147
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.86
    Marker Score: 654
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 0.84
    Marker Score: 294
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,267
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 708
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 396
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 0.74
    Marker Score: 1,795
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.72
    Marker Score: 261
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.7
    Marker Score: 17,936
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.69
    Marker Score: 1,108
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.69
    Marker Score: 438
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.66
    Marker Score: 438
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.65
    Marker Score: 1,622
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.65
    Marker Score: 162
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.63
    Marker Score: 217
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.62
    Marker Score: 172
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.61
    Marker Score: 6,144
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.61
    Marker Score: 326
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.58
    Marker Score: 463
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.58
    Marker Score: 697
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.57
    Marker Score: 284
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.53
    Marker Score: 591
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.49
    Marker Score: 158
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.48
    Marker Score: 463
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 0.46
    Marker Score: 144
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.41
    Marker Score: 270
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.41
    Marker Score: 707
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.39
    Marker Score: 200
  • Cell Name: colon macrophage (CL0009038)
    Fold Change: 0.38
    Marker Score: 106
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.38
    Marker Score: 101
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 0.38
    Marker Score: 100
  • Cell Name: Langerhans cell (CL0000453)
    Fold Change: 0.38
    Marker Score: 113
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.37
    Marker Score: 369
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.37
    Marker Score: 666
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.35
    Marker Score: 122
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.35
    Marker Score: 459
  • Cell Name: pre-conventional dendritic cell (CL0002010)
    Fold Change: 0.35
    Marker Score: 103
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.34
    Marker Score: 383
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.32
    Marker Score: 158
  • Cell Name: promonocyte (CL0000559)
    Fold Change: 0.32
    Marker Score: 206
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 0.31
    Marker Score: 227
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.31
    Marker Score: 213
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.31
    Marker Score: 210
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 0.28
    Marker Score: 341
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 0.28
    Marker Score: 166
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.27
    Marker Score: 154
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.25
    Marker Score: 689
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.25
    Marker Score: 147
  • Cell Name: B-2 B cell (CL0000822)
    Fold Change: 0.24
    Marker Score: 296
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.24
    Marker Score: 134
  • Cell Name: B-1a B cell (CL0000820)
    Fold Change: 0.23
    Marker Score: 55
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.23
    Marker Score: 139
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: 0.23
    Marker Score: 99
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.18
    Marker Score: 63
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 0.18
    Marker Score: 153
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.17
    Marker Score: 96
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.17
    Marker Score: 269
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.16
    Marker Score: 1,608
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.16
    Marker Score: 162
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.15
    Marker Score: 170
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.14
    Marker Score: 239
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.14
    Marker Score: 80
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.13
    Marker Score: 66
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 0.13
    Marker Score: 30
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.13
    Marker Score: 30
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 0.13
    Marker Score: 57
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.13
    Marker Score: 262
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.13
    Marker Score: 31
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.12
    Marker Score: 119
  • Cell Name: phagocyte (CL0000234)
    Fold Change: 0.12
    Marker Score: 41
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.12
    Marker Score: 55
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 0.12
    Marker Score: 31
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.12
    Marker Score: 31
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.12
    Marker Score: 81
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.12
    Marker Score: 30

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Immunoregulatory function:** LILRB4 is a negative regulator of the adaptive immune response, inhibiting the activation and proliferation of T cells, as well as the production of cytokines and chemokines. 2. **Expression on immune cells:** LILRB4 is expressed on the surface of myeloid dendritic cells, monocytes, macrophages, and regulatory T cells, indicating its role in modulating immune responses. 3. **Inhibition of Fc receptor-mediated signaling:** LILRB4 inhibits Fc receptor-mediated signaling, which is essential for the activation of immune cells. 4. **Regulation of cytokine production:** LILRB4 regulates the production of various cytokines, including IL-10, IL-1β, and IL-6, which are involved in inflammatory responses. 5. **Signaling pathways:** LILRB4 is involved in various signaling pathways, including the cytoplasmic side of the plasma membrane, extracellular exosome, and Fc receptor-mediated inhibitory signaling pathway. **Pathways and Functions:** 1. **Adaptive immune response:** LILRB4 is involved in the negative regulation of activated T cell proliferation, which is essential for preventing excessive immune activation. 2. **Inhibitory mHC class I receptor activity:** LILRB4 inhibits the activation of T cells through its interaction with MHC class I molecules. 3. **Interleukin-10-mediated signaling pathway:** LILRB4 regulates the production of IL-10, which is a key anti-inflammatory cytokine. 4. **Negative regulation of activated T cell differentiation:** LILRB4 inhibits the differentiation of activated T cells into effector cells. 5. **Regulation of cytokine production:** LILRB4 regulates the production of various cytokines, including IL-10, IL-1β, and IL-6, which are involved in inflammatory responses. **Clinical Significance:** 1. **Immunotherapy:** LILRB4 is a potential target for immunotherapy, as its inhibition can enhance the efficacy of cancer treatments. 2. **Autoimmune diseases:** LILRB4 may play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and type 1 diabetes, by regulating the immune response. 3. **Infectious diseases:** LILRB4 may be involved in the regulation of immune responses to infectious diseases, such as HIV and tuberculosis. 4. **Cancer:** LILRB4 may be involved in the regulation of immune responses to cancer, including the inhibition of tumor necrosis factor production and the promotion of regulatory T cell differentiation. In conclusion, LILRB4 is a critical component of the immune system that plays a pivotal role in regulating the adaptive immune response. Its expression on the surface of various immune cells and its involvement in various immunoregulatory pathways make it an essential target for the development of immunotherapies and the study of immune diseases.

Genular Protein ID: 3558230216

Symbol: LIRB4_HUMAN

Name: Leukocyte immunoglobulin-like receptor subfamily B member 4

UniProtKB Accession Codes:

Q8NHJ6 A8MVL8 O15468 O75021 Q6FGQ9 Q8N1C7 Q8NHL5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 4 ExpressionAtlas 1 GO 43 Gene3D 1 GeneCards 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9278324

Title: Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

PubMed ID: 9278324

PubMed ID: 9548455

Title: A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

PubMed ID: 9548455

PubMed ID: 10941837

Title: Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4.

PubMed ID: 10941837

DOI: 10.1007/s002510000183

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9151699

Title: A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing.

PubMed ID: 9151699

DOI: 10.1084/jem.185.10.1743

PubMed ID: 11875462

Title: Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4.

PubMed ID: 11875462

DOI: 10.1038/ni760

PubMed ID: 16493035

Title: Recombinant Ig-like transcript 3-Fc modulates T cell responses via induction of Th anergy and differentiation of CD8+ T suppressor cells.

PubMed ID: 16493035

DOI: 10.4049/jimmunol.176.5.2790

PubMed ID: 19860908

Title: The inhibitory receptor LILRB4 (ILT3) modulates antigen presenting cell phenotype and, along with LILRB2 (ILT4), is upregulated in response to Salmonella infection.

PubMed ID: 19860908

DOI: 10.1186/1471-2172-10-56

PubMed ID: 19833736

Title: Leukocyte Ig-like receptor B4 (LILRB4) is a potent inhibitor of FcgammaRI-mediated monocyte activation via dephosphorylation of multiple kinases.

PubMed ID: 19833736

DOI: 10.1074/jbc.m109.035683

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29263213

Title: ILT3.Fc-CD166 Interaction Induces Inactivation of p70 S6 Kinase and Inhibits Tumor Cell Growth.

PubMed ID: 29263213

DOI: 10.4049/jimmunol.1700553

PubMed ID: 30333625

Title: LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.

PubMed ID: 30333625

DOI: 10.1038/s41586-018-0615-z

PubMed ID: 34089617

Title: Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice.

PubMed ID: 34089617

DOI: 10.1093/intimm/dxab028

PubMed ID: 21454581

Title: Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.

PubMed ID: 21454581

DOI: 10.1074/jbc.m111.221028

Sequence Information:

  • Length: 448
  • Mass: 49356
  • Checksum: C18C21694F283FBB
  • Sequence:
    • MIPTFTALLC LGLSLGPRTH MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL 
DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA 
YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF 
PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEDPRPSPTR SVSTAAGPED 
QPLMPTGSVP HSGLRRHWEV LIGVLVVSIL LLSLLLFLLL QHWRQGKHRT LAQRQADFQR 
PPGAAEPEPK DGGLQRRSSP AADVQGENFC AAVKNTQPED GVEMDTRQSP HDEDPQAVTY 
AKVKHSRPRR EMASPPSPLS GEFLDTKDRQ AEEDRQMDTE AAASEAPQDV TYAQLHSFTL 
RQKATEPPPS QEGASPAEPS VYATLAIH

Genular Protein ID: 3203344391

Symbol: A0A0A0MSZ8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MSZ8

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 4 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 447
  • Mass: 49198
  • Checksum: 60368274B7C6F63D
  • Sequence:
    • MIPTFTALLC LGLSLGPRTH MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL 
DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA 
YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF 
PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEGPRPSPTR SVSTAAGPED 
QPLMPTGSVP HSGLRRHWEV LIGVLVVSIL LLSLLLFLLL QHWRQGKHRT LAQRQADFQR 
PPGAAEPEPK DGGLQRRSSP AADVQGENFC AAVKNTQPED GVEMDTRSPH DEDPQAVTYA 
KVKHSRPRRE MASPPSPLSG EFLDTKDRQA EEDRQMDTEA AASEAPQDVT YARLHSFTLR 
QKATEPPPSQ EGASPAEPSV YATLAIH

Genular Protein ID: 3964452018

Symbol: A0A8Q3SHR1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8Q3SHR1

Database IDs:

ARBA 1 CDD 1 CTD 1 EMBL 2 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 KEGG 1 MANE-Select 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 448
  • Mass: 49326
  • Checksum: 76D1E0B7AD3A1399
  • Sequence:
    • MIPTFTALLC LGLSLGPRTH MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL 
DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA 
YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF 
PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEGPRPSPTR SVSTAAGPED 
QPLMPTGSVP HSGLRRHWEV LIGVLVVSIL LLSLLLFLLL QHWRQGKHRT LAQRQADFQR 
PPGAAEPEPK DGGLQRRSSP AADVQGENFC AAVKNTQPED GVEMDTRQSP HDEDPQAVTY 
AKVKHSRPRR EMASPPSPLS GEFLDTKDRQ AEEDRQMDTE AAASEAPQDV TYARLHSFTL 
RQKATEPPPS QEGASPAEPS VYATLAIH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.