RAB35 | ENSG00000111737 | NCBI 11021

Details for: RAB35

Gene ID: 11021

Symbol: RAB35

Ensembl ID: ENSG00000111737

Description: RAB35, member RAS oncogene family

Associated with

Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Rab gefs exchange gtp for gdp on rabs
(R-HSA-8876198)
Rab geranylgeranylation
(R-HSA-8873719)
Rab regulation of trafficking
(R-HSA-9007101)
Tbc/rabgaps
(R-HSA-8854214)
Vesicle-mediated transport
(R-HSA-5653656)
Antigen processing and presentation
(GO:0019882)
Cell projection membrane
(GO:0031253)
Cellular response to nerve growth factor stimulus
(GO:1990090)
Clathrin-coated endocytic vesicle
(GO:0045334)
Clathrin-coated endocytic vesicle membrane
(GO:0030669)
Clathrin-coated pit
(GO:0005905)
Cytosol
(GO:0005829)
Endocytic recycling
(GO:0032456)
Endosomal transport
(GO:0016197)
Endosome membrane
(GO:0010008)
Extracellular exosome
(GO:0070062)
Gdp binding
(GO:0019003)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Intercellular bridge
(GO:0045171)
Melanosome
(GO:0042470)
Mitotic cytokinesis
(GO:0000281)
Neuron projection development
(GO:0031175)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Plasma membrane
(GO:0005886)
Plasma membrane to endosome transport
(GO:0048227)
Protein binding
(GO:0005515)
Protein localization
(GO:0008104)
Protein localization to endosome
(GO:0036010)
Protein transport
(GO:0015031)
Rab protein signal transduction
(GO:0032482)
Recycling endosome membrane
(GO:0055038)

Other Information

Proteins

Ras-related protein Rab-35

Genular Protein ID: 4057798855

Symbol: RAB35_HUMAN

Name: Ras-related protein Rab-35

UniProtKB Accession Codes:

Q15286 B2R6E0 B4E390

Database IDs:

Citations:

PubMed ID: 7811277

Title: Molecular cloning of two small GTP-binding proteins from human skeletal muscle.

PubMed ID: 7811277

DOI: 10.1006/bbrc.1994.2889

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16950109

Title: Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis.

PubMed ID: 16950109

DOI: 10.1016/j.cub.2006.07.020

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 20154091

Title: The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.

PubMed ID: 20154091

DOI: 10.1074/jbc.m109.050930

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21822290

Title: Modulation of Rab GTPase function by a protein phosphocholine transferase.

PubMed ID: 21822290

DOI: 10.1038/nature10335

PubMed ID: 22307087

Title: Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins.

PubMed ID: 22307087

DOI: 10.1038/emboj.2012.16

PubMed ID: 21951725

Title: MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.

PubMed ID: 21951725

DOI: 10.1111/j.1600-0854.2011.01294.x

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29125462

Title: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

PubMed ID: 29125462

DOI: 10.7554/elife.31012

PubMed ID: 22065758

Title: Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.

PubMed ID: 22065758

DOI: 10.1073/pnas.1110415108

Sequence Information:

Length: 201
Mass: 23025
Checksum: 31EB15D6D42E076E
Sequence:

MARDYDHLFK LLIIGDSGVG KSSLLLRFAD NTFSGSYITT IGVDFKIRTV EINGEKVKLQ 
IWDTAGQERF RTITSTYYRG THGVIVVYDV TSAESFVNVK RWLHEINQNC DDVCRILVGN 
KNDDPERKVV ETEDAYKFAG QMGIQLFETS AKENVNVEEM FNCITELVLR AKKDNLAKQQ 
QQQQNDVVKL TKNSKRKKRC C

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RAB35

Associated with

Other Information

Molecular cloning of two small GTP-binding proteins from human skeletal muscle. PubMed ID: 7811277

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The finished DNA sequence of human chromosome 12. PubMed ID: 16541075

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis. PubMed ID: 16950109

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. PubMed ID: 17081065

The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery. PubMed ID: 20154091

Initial characterization of the human central proteome. PubMed ID: 21269460

Modulation of Rab GTPase function by a protein phosphocholine transferase. PubMed ID: 21822290

Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins. PubMed ID: 22307087

MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a. PubMed ID: 21951725

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. PubMed ID: 29125462

Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. PubMed ID: 22065758