Details for: CHAT

Gene ID: 1103

Symbol: CHAT

Ensembl ID: ENSG00000070748

Description: choline O-acetyltransferase

Associated with

Other Information

Genular Protein ID: 1959035332

Symbol: CLAT_HUMAN

Name: Choline O-acetyltransferase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1337937

Title: A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells.

PubMed ID: 1337937

DOI: 10.1016/0169-328x(92)90237-6

PubMed ID: 11172068

Title: Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans.

PubMed ID: 11172068

DOI: 10.1073/pnas.98.4.2017

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1388731

Title: Two mRNAs are transcribed from the human gene for choline acetyltransferase.

PubMed ID: 1388731

DOI: 10.1089/dna.1992.11.593

PubMed ID: 1339386

Title: Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions.

PubMed ID: 1339386

DOI: 10.1016/0888-7543(92)90395-9

PubMed ID: 3183663

Title: Conservation of amino acid sequences between human and porcine choline acetyltransferase.

PubMed ID: 3183663

DOI: 10.1111/j.1471-4159.1988.tb01166.x

PubMed ID: 1784419

Title: Isolation and sub-chromosomal localization of a DNA fragment of the human choline acetyltransferase gene.

PubMed ID: 1784419

DOI: 10.1016/0304-3940(91)90299-9

PubMed ID: 17144655

Title: Substrate binding and catalytic mechanism of human choline acetyltransferase.

PubMed ID: 17144655

DOI: 10.1021/bi061536l

PubMed ID: 12756141

Title: Congenital myasthenic syndrome with episodic apnea in patients homozygous for a CHAT missense mutation.

PubMed ID: 12756141

DOI: 10.1001/archneur.60.5.761

Sequence Information:

  • Length: 748
  • Mass: 82536
  • Checksum: A902364081915391
  • Sequence:
  • MGLRTAKKRG LGGGGKWKRE EGGGTRGRRE VRPACFLQSG GRGDPGDVGG PAGNPGCSPH 
    PRAATRPPPL PAHTPAHTPE WCGAASAEAA EPRRAGPHLC IPAPGLTKTP ILEKVPRKMA 
    AKTPSSEESG LPKLPVPPLQ QTLATYLQCM RHLVSEEQFR KSQAIVQQFG APGGLGETLQ 
    QKLLERQEKT ANWVSEYWLN DMYLNNRLAL PVNSSPAVIF ARQHFPGTDD QLRFAASLIS 
    GVLSYKALLD SHSIPTDCAK GQLSGQPLCM KQYYGLFSSY RLPGHTQDTL VAQNSSIMPE 
    PEHVIVACCN QFFVLDVVIN FRRLSEGDLF TQLRKIVKMA SNEDERLPPI GLLTSDGRSE 
    WAEARTVLVK DSTNRDSLDM IERCICLVCL DAPGGVELSD THRALQLLHG GGYSKNGANR 
    WYDKSLQFVV GRDGTCGVVC EHSPFDGIVL VQCTEHLLKH VTQSSRKLIR ADSVSELPAP 
    RRLRWKCSPE IQGHLASSAE KLQRIVKNLD FIVYKFDNYG KTFIKKQKCS PDAFIQVALQ 
    LAFYRLHRRL VPTYESASIR RFQEGRVDNI RSATPEALAF VRAVTDHKAA VPASEKLLLL 
    KDAIRAQTAY TVMAITGMAI DNHLLALREL ARAMCKELPE MFMDETYLMS NRFVLSTSQV 
    PTTTEMFCCY GPVVPNGYGA CYNPQPETIL FCISSFHSCK ETSSSKFAKA VEESLIDMRD 
    LCSLLPPTES KPLATKEKAT RPSQGHQP

Genular Protein ID: 1303887906

Symbol: Q6LEN6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1337937

Title: A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells.

PubMed ID: 1337937

DOI: 10.1016/0169-328X(92)90237-6

PubMed ID: 1400357

Title: Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region.

PubMed ID: 1400357

PubMed ID: 8479291

Title: Multiple mRNA species of choline acetyltransferase from rat spinal cord.

PubMed ID: 8479291

DOI: 10.1016/0169-328X(93)90174-N

PubMed ID: 9073174

Title: Human choline acetyltransferase mRNAs with different 5'-region produce a 69-kDa major translation product.

PubMed ID: 9073174

DOI: 10.1016/S0169-328X(96)00231-8

Sequence Information:

  • Length: 138
  • Mass: 15355
  • Checksum: E760480EC357D2EA
  • Sequence:
  • MAAKTPSSEE SGLPKLPVPP LQQTLATYLQ CMRHLVSEEQ FRKSQAIVQQ FGAPGGLGET 
    LQQKLLERQE KTANWVSEYW LNDMYLNNRL ALPVNSSPAV IFARQHFPGT DDQLRFAASL 
    ISGVLSYKAL LDSHSIPT

Genular Protein ID: 3644719406

Symbol: Q6LEN5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1337937

Title: A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells.

PubMed ID: 1337937

DOI: 10.1016/0169-328X(92)90237-6

PubMed ID: 1400357

Title: Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region.

PubMed ID: 1400357

PubMed ID: 8479291

Title: Multiple mRNA species of choline acetyltransferase from rat spinal cord.

PubMed ID: 8479291

DOI: 10.1016/0169-328X(93)90174-N

PubMed ID: 7616604

Title: Human choline acetyltransferase gene: localization of alternative first exons.

PubMed ID: 7616604

DOI: 10.1002/jnr.490400402

PubMed ID: 9073174

Title: Human choline acetyltransferase mRNAs with different 5'-region produce a 69-kDa major translation product.

PubMed ID: 9073174

DOI: 10.1016/S0169-328X(96)00231-8

Sequence Information:

  • Length: 34
  • Mass: 3724
  • Checksum: 22E9860105EF4104
  • Sequence:
  • MAAKTPSSEE SGLPKLPVPP LQQTLATYLQ CMRH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.