Details for: RCC1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.02
Marker Score: 2289 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.63
Marker Score: 6328 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167795 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.41
Marker Score: 1250 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.38
Marker Score: 1268 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.16
Marker Score: 3161 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.13
Marker Score: 1137 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.13
Marker Score: 7216 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.1
Marker Score: 2764 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 1.1
Marker Score: 826 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.08
Marker Score: 733 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.07
Marker Score: 726 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.06
Marker Score: 4407 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.03
Marker Score: 3044 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.03
Marker Score: 2164.5 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 1.01
Marker Score: 353 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71727 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47952 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.99
Marker Score: 15892 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.99
Marker Score: 686 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.98
Marker Score: 924 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30394 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 488 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2402 - Cell Name: Unknown (CL0000548)
Fold Change: 0.94
Marker Score: 688 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.94
Marker Score: 444 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5246 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.91
Marker Score: 1145.5 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2712 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.88
Marker Score: 440 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5294 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 311 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.86
Marker Score: 548 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.86
Marker Score: 917 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.86
Marker Score: 218 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.85
Marker Score: 2321 - Cell Name: malignant cell (CL0001064)
Fold Change: 0.83
Marker Score: 11186 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.83
Marker Score: 208 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.83
Marker Score: 1340 - Cell Name: contractile cell (CL0000183)
Fold Change: 0.82
Marker Score: 444 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.82
Marker Score: 12808 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.82
Marker Score: 1087 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.82
Marker Score: 3337 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.81
Marker Score: 1379 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.81
Marker Score: 42820 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 321 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 596 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.78
Marker Score: 378 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.78
Marker Score: 1128 - Cell Name: follicular B cell (CL0000843)
Fold Change: 0.77
Marker Score: 838.5 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.77
Marker Score: 1613 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 0.77
Marker Score: 1322 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.77
Marker Score: 1132.5 - Cell Name: stem cell (CL0000034)
Fold Change: 0.77
Marker Score: 1822 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.75
Marker Score: 2361 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 0.74
Marker Score: 272 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 380 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.71
Marker Score: 1025 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.71
Marker Score: 2797 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.71
Marker Score: 744 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.71
Marker Score: 443 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.7
Marker Score: 198 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.69
Marker Score: 2908 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.69
Marker Score: 278 - Cell Name: brush cell (CL0002204)
Fold Change: 0.69
Marker Score: 632 - Cell Name: club cell (CL0000158)
Fold Change: 0.69
Marker Score: 807 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.69
Marker Score: 977 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.69
Marker Score: 378 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.68
Marker Score: 729 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.68
Marker Score: 452 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.67
Marker Score: 1571 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.66
Marker Score: 691 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.66
Marker Score: 395.5 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.65
Marker Score: 4210.5 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.65
Marker Score: 403.5 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.65
Marker Score: 171 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.64
Marker Score: 267 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.64
Marker Score: 1136 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.64
Marker Score: 461 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.64
Marker Score: 312 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.63
Marker Score: 451 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.63
Marker Score: 150 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.63
Marker Score: 2331 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.63
Marker Score: 188 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.62
Marker Score: 309 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.62
Marker Score: 6307 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.62
Marker Score: 200 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.62
Marker Score: 407.5 - Cell Name: Unknown (CL0002371)
Fold Change: 0.62
Marker Score: 657 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.62
Marker Score: 767 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.61
Marker Score: 6904.5 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 0.61
Marker Score: 1067 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.61
Marker Score: 2639 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.61
Marker Score: 2102 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.61
Marker Score: 21043 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.61
Marker Score: 1424 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.6
Marker Score: 399 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.58
Marker Score: 7710 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.58
Marker Score: 519
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Other Information
Genular Protein ID: 3790097226
Symbol: RCC1_HUMAN
Name: Regulator of chromosome condensation
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3678831
Title: Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.
PubMed ID: 3678831
DOI: 10.1101/gad.1.6.585
PubMed ID: 1769659
Title: Complete nucleotide sequence of the human RCC1 gene involved in coupling between DNA replication and mitosis.
PubMed ID: 1769659
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7983178
Title: Mammalian cells have two functional RCC1 proteins produced by alternative splicing.
PubMed ID: 7983178
PubMed ID: 2236072
Title: A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation.
PubMed ID: 2236072
PubMed ID: 1944575
Title: Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1.
PubMed ID: 1944575
DOI: 10.1038/354080a0
PubMed ID: 12194828
Title: Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells.
PubMed ID: 12194828
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16820410
Title: Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.
PubMed ID: 16820410
DOI: 10.1242/jcs.03046
PubMed ID: 17435751
Title: N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.
PubMed ID: 17435751
DOI: 10.1038/ncb1572
PubMed ID: 18762580
Title: Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1.
PubMed ID: 18762580
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20668449
Title: NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein.
PubMed ID: 20668449
DOI: 10.1038/nature09343
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22215983
Title: Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts.
PubMed ID: 22215983
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 29040603
Title: Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation.
PubMed ID: 29040603
DOI: 10.1093/jmcb/mjx045
PubMed ID: 34564892
Title: Dominant KPNA3 Mutations Cause Infantile-Onset Hereditary Spastic Paraplegia.
PubMed ID: 34564892
DOI: 10.1002/ana.26228
PubMed ID: 9510255
Title: The 1.7-A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller.
PubMed ID: 9510255
DOI: 10.1038/32204
PubMed ID: 11336674
Title: Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1).
PubMed ID: 11336674
PubMed ID: 29042532
Title: Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
PubMed ID: 29042532
Sequence Information:
- Length: 421
- Mass: 44969
- Checksum: F6D225AF81928305
- Sequence:
MSPKRIAKRR SPPADAIPKS KKVKVSHRSH STEPGLVLTL GQGDVGQLGL GENVMERKKP ALVSIPEDVV QAEAGGMHTV CLSKSGQVYS FGCNDEGALG RDTSVEGSEM VPGKVELQEK VVQVSAGDSH TAALTDDGRV FLWGSFRDNN GVIGLLEPMK KSMVPVQVQL DVPVVKVASG NDHLVMLTAD GDLYTLGCGE QGQLGRVPEL FANRGGRQGL ERLLVPKCVM LKSRGSRGHV RFQDAFCGAY FTFAISHEGH VYGFGLSNYH QLGTPGTESC FIPQNLTSFK NSTKSWVGFS GGQHHTVCMD SEGKAYSLGR AEYGRLGLGE GAEEKSIPTL ISRLPAVSSV ACGASVGYAV TKDGRVFAWG MGTNYQLGTG QDEDAWSPVE MMGKQLENRV VLSVSSGGQH TVLLVKDKEQ S
Genular Protein ID: 3876311110
Symbol: A0A0S2Z404_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 452
- Mass: 48146
- Checksum: A31255E99A01A25F
- Sequence:
MSPKRIAKRR SPPADAIPKS KKVKDTRAAA SRRVPGARSC QGACGPSPPD QKTRPVSHRS HSTEPGLVLT LGQGDVGQLG LGENVMERKK PALVSIPEDV VQAEAGGMHT VCLSKSGQVY SFGCNDEGAL GRDTSVEGSE MVPGKVELQE KVVQVSAGDS HTAALTDDGR VFLWGSFRDN NGVIGLLEPM KKSMVPVQVQ LDVPVVKVAS GNDHLVMLTA DGDLYTLGCG EQGQLGRVPE LFANRGGRQG LERLLVPKCV MLKSRGSRGH VRFQDAFCGA YFTFAISHEG HVYGFGLSNY HQLGTPGTES CFIPQNLTSF KNSTKSWVGF SGGQHHTVCM DSEGKAYSLG RAEYGRLGLG EGAEEKSIPT LISRLPAVSS VACGASVGYA VTKDGRVFAW GMGTNYQLGT GQDEDAWSPV EMMGKQLENR VVLSVSSGGQ HTVLLVKDKE QS
Genular Protein ID: 1865271710
Symbol: A0A0S2Z3I4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 438
- Mass: 46753
- Checksum: 223B8046E301E535
- Sequence:
MSPKRIAKRR SPPADAIPKS KKVKDTRAAA SRRVPGARSC QVSHRSHSTE PGLVLTLGQG DVGQLGLGEN VMERKKPALV SIPEDVVQAE AGGMHTVCLS KSGQVYSFGC NDEGALGRDT SVEGSEMVPG KVELQEKVVQ VSAGDSHTAA LTDDGRVFLW GSFRDNNGVI GLLEPMKKSM VPVQVQLDVP VVKVASGNDH LVMLTADGDL YTLGCGEQGQ LGRVPELFAN RGGRQGLERL LVPKCVMLKS RGSRGHVRFQ DAFCGAYFTF AISHEGHVYG FGLSNYHQLG TPGTESCFIP QNLTSFKNST KSWVGFSGGQ HHTVCMDSEG KAYSLGRAEY GRLGLGEGAE EKSIPTLISR LPAVSSVACG ASVGYAVTKD GRVFAWGMGT NYQLGTGQDE DAWSPVEMMG KQLENRVVLS VSSGGQHTVL LVKDKEQS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.