Details for: ADRM1

Gene ID: 11047

Symbol: ADRM1

Ensembl ID: ENSG00000130706

Description: ADRM1 26S proteasome ubiquitin receptor

Associated with

Other Information

Genular Protein ID: 561572428

Symbol: ADRM1_HUMAN

Name: Proteasomal ubiquitin receptor ADRM1

UniProtKB Accession Codes:

Q16186 A0PKB1 Q96FJ7 Q9H1P2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 25 PDBsum 18 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 5 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8033103

Title: Molecular cloning and characterization of the complementary DNA of an M(r) 110,000 antigen expressed by human gastric carcinoma cells and upregulated by gamma-interferon.

PubMed ID: 8033103

PubMed ID: 16990800

Title: A novel proteasome-interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.

PubMed ID: 16990800

DOI: 10.1038/sj.emboj.7601338

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17139257

Title: hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37.

PubMed ID: 17139257

DOI: 10.1038/sj.emboj.7601450

PubMed ID: 16815440

Title: Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor.

PubMed ID: 16815440

DOI: 10.1016/j.jmb.2006.06.011

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16906146

Title: Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

PubMed ID: 16906146

DOI: 10.1038/ncb1460

PubMed ID: 17323924

Title: Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.

PubMed ID: 17323924

DOI: 10.1021/bi061994u

PubMed ID: 18497817

Title: Proteasome subunit Rpn13 is a novel ubiquitin receptor.

PubMed ID: 18497817

DOI: 10.1038/nature06926

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24811749

Title: Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

PubMed ID: 24811749

DOI: 10.1002/embj.201386906

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31375563

Title: Acute unfolding of a single protein immediately stimulates recruitment of ubiquitin protein ligase E3C (UBE3C) to 26S proteasomes.

PubMed ID: 31375563

DOI: 10.1074/jbc.ra119.009654

PubMed ID: 20471946

Title: Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2.

PubMed ID: 20471946

DOI: 10.1016/j.molcel.2010.04.019

PubMed ID: 24752541

Title: Mechanism of the Rpn13-induced activation of Uch37.

PubMed ID: 24752541

DOI: 10.1007/s13238-014-0046-z

PubMed ID: 25702870

Title: Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G.

PubMed ID: 25702870

DOI: 10.1016/j.molcel.2014.12.039

PubMed ID: 25702872

Title: Structural basis for the activation and inhibition of the UCH37 deubiquitylase.

PubMed ID: 25702872

DOI: 10.1016/j.molcel.2015.01.016

PubMed ID: 27396824

Title: Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 reveal distinct binding mechanisms between substrate receptors and shuttle factors of the proteasome.

PubMed ID: 27396824

DOI: 10.1016/j.str.2016.05.018

Sequence Information:

  • Length: 407
  • Mass: 42153
  • Checksum: 2D38811DCA231864
  • Sequence:
    • MTTSGALFPS LVPGSRGASN KYLVEFRAGK MSLKGTTVTP DKRKGLVYIQ QTDDSLIHFC 
WKDRTSGNVE DDLIIFPDDC EFKRVPQCPS GRVYVLKFKA GSKRLFFWMQ EPKTDQDEEH 
CRKVNEYLNN PPMPGALGAS GSSGHELSAL GGEGGLQSLL GNMSHSQLMQ LIGPAGLGGL 
GGLGALTGPG LASLLGSSGP PGSSSSSSSR SQSAAVTPSS TTSSTRATPA PSAPAAASAT 
SPSPAPSSGN GASTAASPTQ PIQLSDLQSI LATMNVPAGP AGGQQVDLAS VLTPEIMAPI 
LANADVQERL LPYLPSGESL PQTADEIQNT LTSPQFQQAL GMFSAALASG QLGPLMCQFG 
LPAEAVEAAN KGDVEAFAKA MQNNAKPEQK EGDTKDKKDE EEDMSLD

Genular Protein ID: 3091870365

Symbol: A0A087WX59_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WX59

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 2 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17323924

Title: Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.

PubMed ID: 17323924

DOI: 10.1021/bi061994u

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 368
  • Mass: 37505
  • Checksum: 6D9C36FA320D7EE0
  • Sequence:
    • MTTSGALFPS LVPGSRGASN KYLVEFRAGK MSLKGTTVTP DKRKGLVYIQ QTDDSLIHFC 
WKDRTSGNVE DEPKTDQDEE HCRKVNEYLN NPPMPGALGA SGSSGHELSA LGGEGGLQSL 
LGNMSHSQLM QLIGPAGLGG LGGLGALTGP GLASLLGSSG PPGSSSSSSS RSQSAAVTPS 
STTSSTRATP APSAPAAASA TSPSPAPSSG NGASTAASPT QPIQLSDLQS ILATMNVPAG 
PAGGQQVDLA SVLTPEIMAP ILANADVQER LLPYLPSGES LPQTADEIQN TLTSPQFQQA 
LGMFSAALAS GQLGPLMCQF GLPAEAVEAA NKGDVEAFAK AMQNNAKPEQ KEGDTKDKKD 
EEEDMSLD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.