Details for: CHD1

Gene ID: 1105

Symbol: CHD1

Ensembl ID: ENSG00000153922

Description: chromodomain helicase DNA binding protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 433.8288
    Cell Significance Index: -67.4800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 257.0144
    Cell Significance Index: -65.1900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 155.7858
    Cell Significance Index: -73.5500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 154.3604
    Cell Significance Index: -62.7100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 138.3593
    Cell Significance Index: -71.1700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 109.6983
    Cell Significance Index: -73.6100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 66.2063
    Cell Significance Index: -63.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 57.9583
    Cell Significance Index: -71.4600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.7647
    Cell Significance Index: -69.0200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.3551
    Cell Significance Index: -72.4300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 16.5947
    Cell Significance Index: -50.9700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.5306
    Cell Significance Index: -33.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.7955
    Cell Significance Index: 74.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.6310
    Cell Significance Index: 147.6400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.3439
    Cell Significance Index: 381.2200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7433
    Cell Significance Index: 345.9700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.6291
    Cell Significance Index: 46.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4212
    Cell Significance Index: 285.0900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2862
    Cell Significance Index: 139.9000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0407
    Cell Significance Index: 54.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9061
    Cell Significance Index: 111.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8649
    Cell Significance Index: 118.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8486
    Cell Significance Index: 65.1200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8328
    Cell Significance Index: 53.7300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7951
    Cell Significance Index: 37.3700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7757
    Cell Significance Index: 278.2400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7225
    Cell Significance Index: 18.0600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7027
    Cell Significance Index: 126.6800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6490
    Cell Significance Index: 448.8600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6308
    Cell Significance Index: 569.5300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5769
    Cell Significance Index: 26.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5698
    Cell Significance Index: 73.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5265
    Cell Significance Index: 14.3300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4801
    Cell Significance Index: 212.2600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4429
    Cell Significance Index: 241.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3725
    Cell Significance Index: 48.1200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3453
    Cell Significance Index: 6.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3401
    Cell Significance Index: 9.8000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2435
    Cell Significance Index: 154.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2406
    Cell Significance Index: 14.7900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2395
    Cell Significance Index: 368.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1933
    Cell Significance Index: 364.0400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1789
    Cell Significance Index: 329.8500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1494
    Cell Significance Index: 28.4400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0992
    Cell Significance Index: 2.5500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0882
    Cell Significance Index: 1.6300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0882
    Cell Significance Index: 1.9100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0762
    Cell Significance Index: 2.1300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0754
    Cell Significance Index: 34.2100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0380
    Cell Significance Index: 2.6900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0309
    Cell Significance Index: 0.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0240
    Cell Significance Index: 32.7000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0098
    Cell Significance Index: 0.6700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0102
    Cell Significance Index: -1.0100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0348
    Cell Significance Index: -5.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0353
    Cell Significance Index: -26.1400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0391
    Cell Significance Index: -24.4200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0443
    Cell Significance Index: -32.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0706
    Cell Significance Index: -2.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0730
    Cell Significance Index: -55.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0807
    Cell Significance Index: -6.0200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0870
    Cell Significance Index: -49.0400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1338
    Cell Significance Index: -15.7800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1526
    Cell Significance Index: -17.4200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1666
    Cell Significance Index: -7.7700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1814
    Cell Significance Index: -18.5300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2118
    Cell Significance Index: -60.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2123
    Cell Significance Index: -44.7300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2243
    Cell Significance Index: -6.0000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2257
    Cell Significance Index: -32.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2658
    Cell Significance Index: -13.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2965
    Cell Significance Index: -19.9400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3286
    Cell Significance Index: -5.5400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3623
    Cell Significance Index: -42.2300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3728
    Cell Significance Index: -42.7200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4649
    Cell Significance Index: -16.1600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4837
    Cell Significance Index: -12.9600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4852
    Cell Significance Index: -21.4600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4932
    Cell Significance Index: -2.9800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4934
    Cell Significance Index: -31.1000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5000
    Cell Significance Index: -5.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5024
    Cell Significance Index: -52.3100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5242
    Cell Significance Index: -7.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5570
    Cell Significance Index: -14.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5878
    Cell Significance Index: -8.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.6032
    Cell Significance Index: -22.8400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6302
    Cell Significance Index: -33.0900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7100
    Cell Significance Index: -15.1200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8130
    Cell Significance Index: -64.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8617
    Cell Significance Index: -27.6000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.9025
    Cell Significance Index: -18.8900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9034
    Cell Significance Index: -15.1200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.9492
    Cell Significance Index: -7.7400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.9764
    Cell Significance Index: -17.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0638
    Cell Significance Index: -65.2200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.0791
    Cell Significance Index: -25.8800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.1474
    Cell Significance Index: -26.5100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -1.1627
    Cell Significance Index: -28.3700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.2577
    Cell Significance Index: -32.1300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.3069
    Cell Significance Index: -19.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CHD1 is a 43-kDa protein that belongs to the CHD family of chromatin remodelers. It possesses a chromodomain, a helicase domain, and a DNA binding domain, which enable it to interact with chromatin and other proteins. CHD1 is characterized by its ability to remodel chromatin structure, which is essential for the regulation of gene expression. It has been shown to interact with various transcription factors and co-regulators, influencing the recruitment of RNA polymerase II to specific gene loci. **Pathways and Functions:** CHD1 is involved in several key pathways, including: 1. **ATP-dependent chromatin remodeler activity:** CHD1 utilizes ATP hydrolysis to remodel chromatin structure, which is essential for the regulation of gene expression. 2. **DNA binding and helicase activity:** CHD1 binds to specific DNA sequences and exhibits helicase activity, which enables it to unwind DNA and facilitate chromatin remodeling. 3. **Chromatin binding and remodeling:** CHD1 interacts with histones and other chromatin-associated proteins to remodel chromatin structure and regulate gene expression. 4. **Esr-mediated signaling:** CHD1 has been shown to interact with estrogen receptor (ER) signaling pathways, influencing the regulation of estrogen-dependent gene expression. 5. **Histone binding and methylated histone binding:** CHD1 interacts with histones and methylated histones, which is essential for the regulation of chromatin structure and gene expression. **Clinical Significance:** CHD1 has been implicated in various diseases, including: 1. **Cancer:** CHD1 has been shown to be overexpressed in several types of cancer, including prostate cancer, breast cancer, and leukemia. Its overexpression is associated with poor prognosis and reduced survival rates. 2. **Immune disorders:** CHD1 has been implicated in the regulation of immune responses, including T-cell development and function. Dysregulation of CHD1 has been associated with autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Neurological disorders:** CHD1 has been implicated in the regulation of neuronal function and development. Dysregulation of CHD1 has been associated with neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, CHD1 is a multifunctional protein that plays a crucial role in chromatin remodeling, transcriptional regulation, and immune responses. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms of CHD1 and its potential therapeutic applications.

Genular Protein ID: 3286497535

Symbol: CHD1_HUMAN

Name: Chromodomain-helicase-DNA-binding protein 1

UniProtKB Accession Codes:

O14646 Q17RZ3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 CarbonylDB 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EC 2 EMBL 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9326634

Title: Characterization of the CHD family of proteins.

PubMed ID: 9326634

DOI: 10.1073/pnas.94.21.11472

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16263726

Title: Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains.

PubMed ID: 16263726

DOI: 10.1074/jbc.c500395200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17433364

Title: Molecular implications of evolutionary differences in CHD double chromodomains.

PubMed ID: 17433364

DOI: 10.1016/j.jmb.2007.03.024

PubMed ID: 18042460

Title: Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing.

PubMed ID: 18042460

DOI: 10.1016/j.molcel.2007.11.010

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28866611

Title: Missense variants in the chromatin remodeler CHD1 are associated with neurodevelopmental disability.

PubMed ID: 28866611

DOI: 10.1136/jmedgenet-2017-104759

PubMed ID: 16372014

Title: Double chromodomains cooperate to recognize the methylated histone H3 tail.

PubMed ID: 16372014

DOI: 10.1038/nature04290

PubMed ID: 27591891

Title: The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain.

PubMed ID: 27591891

DOI: 10.1016/j.jmb.2016.08.028

Sequence Information:

  • Length: 1710
  • Mass: 196688
  • Checksum: D888AAA46FDA31B1
  • Sequence:
    • MNGHSDEESV RNSSGESSQS DDDSGSASGS GSGSSSGSSS DGSSSQSGSS DSDSGSESGS 
QSESESDTSR ENKVQAKPPK VDGAEFWKSS PSILAVQRSA ILKKQQQQQQ QQQHQASSNS 
GSEEDSSSSE DSDDSSSEVK RKKHKDEDWQ MSGSGSPSQS GSDSESEEER EKSSCDETES 
DYEPKNKVKS RKPQNRSKSK NGKKILGQKK RQIDSSEEDD DEEDYDNDKR SSRRQATVNV 
SYKEDEEMKT DSDDLLEVCG EDVPQPEEEE FETIERFMDC RIGRKGATGA TTTIYAVEAD 
GDPNAGFEKN KEPGEIQYLI KWKGWSHIHN TWETEETLKQ QNVRGMKKLD NYKKKDQETK 
RWLKNASPED VEYYNCQQEL TDDLHKQYQI VERIIAHSNQ KSAAGYPDYY CKWQGLPYSE 
CSWEDGALIS KKFQACIDEY FSRNQSKTTP FKDCKVLKQR PRFVALKKQP SYIGGHEGLE 
LRDYQLNGLN WLAHSWCKGN SCILADEMGL GKTIQTISFL NYLFHEHQLY GPFLLVVPLS 
TLTSWQREIQ TWASQMNAVV YLGDINSRNM IRTHEWTHHQ TKRLKFNILL TTYEILLKDK 
AFLGGLNWAF IGVDEAHRLK NDDSLLYKTL IDFKSNHRLL ITGTPLQNSL KELWSLLHFI 
MPEKFSSWED FEEEHGKGRE YGYASLHKEL EPFLLRRVKK DVEKSLPAKV EQILRMEMSA 
LQKQYYKWIL TRNYKALSKG SKGSTSGFLN IMMELKKCCN HCYLIKPPDN NEFYNKQEAL 
QHLIRSSGKL ILLDKLLIRL RERGNRVLIF SQMVRMLDIL AEYLKYRQFP FQRLDGSIKG 
ELRKQALDHF NAEGSEDFCF LLSTRAGGLG INLASADTVV IFDSDWNPQN DLQAQARAHR 
IGQKKQVNIY RLVTKGSVEE DILERAKKKM VLDHLVIQRM DTTGKTVLHT GSAPSSSTPF 
NKEELSAILK FGAEELFKEP EGEEQEPQEM DIDEILKRAE THENEPGPLT VGDELLSQFK 
VANFSNMDED DIELEPERNS KNWEEIIPED QRRRLEEEER QKELEEIYML PRMRNCAKQI 
SFNGSEGRRS RSRRYSGSDS DSISEGKRPK KRGRPRTIPR ENIKGFSDAE IRRFIKSYKK 
FGGPLERLDA IARDAELVDK SETDLRRLGE LVHNGCIKAL KDSSSGTERT GGRLGKVKGP 
TFRISGVQVN AKLVISHEEE LIPLHKSIPS DPEERKQYTI PCHTKAAHFD IDWGKEDDSN 
LLIGIYEYGY GSWEMIKMDP DLSLTHKILP DDPDKKPQAK QLQTRADYLI KLLSRDLAKK 
EALSGAGSSK RRKARAKKNK AMKSIKVKEE IKSDSSPLPS EKSDEDDDKL SESKSDGRER 
SKKSSVSDAP VHITASGEPV PISEESEELD QKTFSICKER MRPVKAALKQ LDRPEKGLSE 
REQLEHTRQC LIKIGDHITE CLKEYTNPEQ IKQWRKNLWI FVSKFTEFDA RKLHKLYKHA 
IKKRQESQQN SDQNSNLNPH VIRNPDVERL KENTNHDDSS RDSYSSDRHL TQYHDHHKDR 
HQGDSYKKSD SRKRPYSSFS NGKDHRDWDH YKQDSRYYSD REKHRKLDDH RSRDHRSNLE 
GSLKDRSHSD HRSHSDHRLH SDHRSSSEYT HHKSSRDYRY HSDWQMDHRA SSSGPRSPLD 
QRSPYGSRSP FEHSVEHKST PEHTWSSRKT

Genular Protein ID: 62369221

Symbol: B3KT33_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KT33

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 301
  • Mass: 35853
  • Checksum: E0B9ADAA441DD6D1
  • Sequence:
    • MFSFTGVLVI YEVLKKCIGK LISLRVCSIE GCVCVYVFVP GGKEFHEKKL NIFHQTNLIC 
LFLNSSRNLW IFVSKFTEFD ARKLHKLYKH AIKKRQESQQ NSDQNSNLNP HVIRNPDVER 
LKENTNHDDS SRDSYSSDRH LTQYHDHHKD RHQGDSYKKS DSRKRPYSSF SNGKDHRDWD 
HYKQDSRYYS DREKHRKLDD HRSRDHRSNL EGSLKDRSHS DHRSHSDHRL HSDHRSSSEY 
THHKSSRDYR YHSDWQMDHR ASSSGPRSPL DQRSPYGSRS PFEHSVEHKS TPEHTWSSRK 
T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.