Details for: CHD2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: lung goblet cell (CL1000143)
Fold Change: 2.89
Marker Score: 832 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.85
Marker Score: 60,802 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.77
Marker Score: 2,391 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.69
Marker Score: 91,523 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.62
Marker Score: 1,456 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.6
Marker Score: 41,769 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.57
Marker Score: 1,977 - Cell Name: germ cell (CL0000586)
Fold Change: 2.47
Marker Score: 4,323 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.46
Marker Score: 2,094 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.45
Marker Score: 10,238 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.44
Marker Score: 714 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.41
Marker Score: 6,768 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.38
Marker Score: 2,508 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 2.37
Marker Score: 2,729 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.36
Marker Score: 1,241 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.3
Marker Score: 34,325 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.28
Marker Score: 86,677 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 2.24
Marker Score: 1,699 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.23
Marker Score: 5,590 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.22
Marker Score: 17,048 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 2.22
Marker Score: 9,237 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.21
Marker Score: 39,176 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.19
Marker Score: 43,525 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.15
Marker Score: 1,251 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.14
Marker Score: 2,589 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.12
Marker Score: 1,054 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.12
Marker Score: 78,128 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.1
Marker Score: 2,831 - Cell Name: astrocyte (CL0000127)
Fold Change: 2.09
Marker Score: 1,815 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.07
Marker Score: 8,620 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.04
Marker Score: 856 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.03
Marker Score: 7,865 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.03
Marker Score: 2,301 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.03
Marker Score: 8,408 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.01
Marker Score: 2,956 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.96
Marker Score: 1,100 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.95
Marker Score: 9,592 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 1.94
Marker Score: 102,644 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.94
Marker Score: 1,517 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.94
Marker Score: 119,158 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.92
Marker Score: 18,089 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.91
Marker Score: 606 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.9
Marker Score: 2,104 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.9
Marker Score: 454 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.9
Marker Score: 1,133 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.89
Marker Score: 932 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.87
Marker Score: 19,312 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 1.87
Marker Score: 2,577 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 1.86
Marker Score: 12,143 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.86
Marker Score: 904 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.85
Marker Score: 1,079 - Cell Name: neuron (CL0000540)
Fold Change: 1.84
Marker Score: 7,488 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.84
Marker Score: 402 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.83
Marker Score: 1,248 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.83
Marker Score: 788 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.82
Marker Score: 3,320 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.82
Marker Score: 3,989 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.81
Marker Score: 3,491 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.81
Marker Score: 4,341 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.8
Marker Score: 730 - Cell Name: club cell (CL0000158)
Fold Change: 1.8
Marker Score: 2,096 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 1.79
Marker Score: 1,246 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.79
Marker Score: 17,007 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.78
Marker Score: 1,918 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 1.77
Marker Score: 1,454 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.77
Marker Score: 558 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.77
Marker Score: 2,184 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.77
Marker Score: 641 - Cell Name: basal cell (CL0000646)
Fold Change: 1.77
Marker Score: 2,279 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.76
Marker Score: 659 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.76
Marker Score: 718 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.75
Marker Score: 1,612 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.75
Marker Score: 15,026 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 1.75
Marker Score: 514 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.74
Marker Score: 1,851 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.74
Marker Score: 1,542 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.74
Marker Score: 1,162 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.73
Marker Score: 1,709 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.72
Marker Score: 601 - Cell Name: podocyte (CL0000653)
Fold Change: 1.71
Marker Score: 631 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.7
Marker Score: 708 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.7
Marker Score: 17,182 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.69
Marker Score: 682 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.68
Marker Score: 2,371 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 1.67
Marker Score: 374 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 1.67
Marker Score: 1,574 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 1.67
Marker Score: 2,989 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.66
Marker Score: 5,902 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.66
Marker Score: 829 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.66
Marker Score: 3,470 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 1.65
Marker Score: 1,661 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.65
Marker Score: 1,798 - Cell Name: naive T cell (CL0000898)
Fold Change: 1.65
Marker Score: 1,063 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.65
Marker Score: 1,028 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.65
Marker Score: 956 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.64
Marker Score: 4,013 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 1.64
Marker Score: 357 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.62
Marker Score: 7,513 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.62
Marker Score: 2,871 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.61
Marker Score: 441
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3849165456
Symbol: CHD2_HUMAN
Name: Chromodomain-helicase-DNA-binding protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9326634
Title: Characterization of the CHD family of proteins.
PubMed ID: 9326634
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 23708187
Title: Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1.
PubMed ID: 23708187
DOI: 10.1038/ng.2646
PubMed ID: 25356899
Title: De novo mutations in moderate or severe intellectual disability.
PubMed ID: 25356899
PubMed ID: 33798445
Title: Progressive myoclonus epilepsies-Residual unsolved cases have marked genetic heterogeneity including dolichol-dependent protein glycosylation pathway genes.
PubMed ID: 33798445
Sequence Information:
- Length: 1828
- Mass: 211344
- Checksum: 13139D6059210F00
- Sequence:
MMRNKDKSQE EDSSLHSNAS SHSASEEASG SDSGSQSESE QGSDPGSGHG SESNSSSESS ESQSESESES AGSKSQPVLP EAKEKPASKK ERIADVKKMW EEYPDVYGVR RSNRSRQEPS RFNIKEEASS GSESGSPKRR GQRQLKKQEK WKQEPSEDEQ EQGTSAESEP EQKKVKARRP VPRRTVPKPR VKKQPKTQRG KRKKQDSSDE DDDDDEAPKR QTRRRAAKNV SYKEDDDFET DSDDLIEMTG EGVDEQQDNS ETIEKVLDSR LGKKGATGAS TTVYAIEANG DPSGDFDTEK DEGEIQYLIK WKGWSYIHST WESEESLQQQ KVKGLKKLEN FKKKEDEIKQ WLGKVSPEDV EYFNCQQELA SELNKQYQIV ERVIAVKTSK STLGQTDFPA HSRKPAPSNE PEYLCKWMGL PYSECSWEDE ALIGKKFQNC IDSFHSRNNS KTIPTRECKA LKQRPRFVAL KKQPAYLGGE NLELRDYQLE GLNWLAHSWC KNNSVILADE MGLGKTIQTI SFLSYLFHQH QLYGPFLIVV PLSTLTSWQR EFEIWAPEIN VVVYIGDLMS RNTIREYEWI HSQTKRLKFN ALITTYEILL KDKTVLGSIN WAFLGVDEAH RLKNDDSLLY KTLIDFKSNH RLLITGTPLQ NSLKELWSLL HFIMPEKFEF WEDFEEDHGK GRENGYQSLH KVLEPFLLRR VKKDVEKSLP AKVEQILRVE MSALQKQYYK WILTRNYKAL AKGTRGSTSG FLNIVMELKK CCNHCYLIKP PEENERENGQ EILLSLIRSS GKLILLDKLL TRLRERGNRV LIFSQMVRML DILAEYLTIK HYPFQRLDGS IKGEIRKQAL DHFNADGSED FCFLLSTRAG GLGINLASAD TVVIFDSDWN PQNDLQAQAR AHRIGQKKQV NIYRLVTKGT VEEEIIERAK KKMVLDHLVI QRMDTTGRTI LENNSGRSNS NPFNKEELTA ILKFGAEDLF KELEGEESEP QEMDIDEILR LAETRENEVS TSATDELLSQ FKVANFATME DEEELEERPH KDWDEIIPEE QRKKVEEEER QKELEEIYML PRIRSSTKKA QTNDSDSDTE SKRQAQRSSA SESETEDSDD DKKPKRRGRP RSVRKDLVEG FTDAEIRRFI KAYKKFGLPL ERLECIARDA ELVDKSVADL KRLGELIHNS CVSAMQEYEE QLKENASEGK GPGKRRGPTI KISGVQVNVK SIIQHEEEFE MLHKSIPVDP EEKKKYCLTC RVKAAHFDVE WGVEDDSRLL LGIYEHGYGN WELIKTDPEL KLTDKILPVE TDKKPQGKQL QTRADYLLKL LRKGLEKKGA VTGGEEAKLK KRKPRVKKEN KVPRLKEEHG IELSSPRHSD NPSEEGEVKD DGLEKSPMKK KQKKKENKEN KEKQMSSRKD KEGDKERKKS KDKKEKPKSG DAKSSSKSKR SQGPVHITAG SEPVPIGEDE DDDLDQETFS ICKERMRPVK KALKQLDKPD KGLNVQEQLE HTRNCLLKIG DRIAECLKAY SDQEHIKLWR RNLWIFVSKF TEFDARKLHK LYKMAHKKRS QEEEEQKKKD DVTGGKKPFR PEASGSSRDS LISQSHTSHN LHPQKPHLPA SHGPQMHGHP RDNYNHPNKR HFSNADRGDW QRERKFNYGG GNNNPPWGSD RHHQYEQHWY KDHHYGDRRH MDAHRSGSYR PNNMSRKRPY DQYSSDRDHR GHRDYYDRHH HDSKRRRSDE FRPQNYHQQD FRRMSDHRPA MGYHGQGPSD HYRSFHTDKL GEYKQPLPPL HPAVSDPRSP PSQKSPHDSK SPLDHRSPLE RSLEQKNNPD YNWNVRKT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.