Details for: WWP2
Associated with
Other Information
Genular Protein ID: 1302462112
Symbol: WWP2_HUMAN
Name: NEDD4-like E3 ubiquitin-protein ligase WWP2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9169421
Title: Identification of novel human WW domain-containing proteins by cloning of ligand targets.
PubMed ID: 9169421
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9647693
Title: Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.
PubMed ID: 9647693
PubMed ID: 12167593
Title: Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.
PubMed ID: 12167593
PubMed ID: 12450395
Title: Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases.
PubMed ID: 12450395
DOI: 10.1021/bi020125b
PubMed ID: 11748237
Title: N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein.
PubMed ID: 11748237
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17719543
Title: Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.
PubMed ID: 17719543
PubMed ID: 19274063
Title: WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.
PubMed ID: 19274063
DOI: 10.1038/cr.2009.31
PubMed ID: 19343052
Title: Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
PubMed ID: 19343052
PubMed ID: 19651900
Title: The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.
PubMed ID: 19651900
DOI: 10.1128/mcb.00407-09
PubMed ID: 20858735
Title: Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.
PubMed ID: 20858735
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21572392
Title: SCF(FBXL15) regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.
PubMed ID: 21572392
PubMed ID: 21191027
Title: Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.
PubMed ID: 21191027
DOI: 10.1128/jvi.02045-10
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23236378
Title: Mammalian alpha arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with beta arrestins.
PubMed ID: 23236378
PubMed ID: 22315426
Title: Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.
PubMed ID: 22315426
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 26457515
Title: Structure of the HECT domain of human WWP2.
PubMed ID: 26457515
Sequence Information:
- Length: 870
- Mass: 98912
- Checksum: FCCD75CBA61F2204
- Sequence:
MASASSSRAG VALPFEKSQL TLKVVSAKPK VHNRQPRINS YVEVAVDGLP SETKKTGKRI GSSELLWNEI IILNVTAQSH LDLKVWSCHT LRNELLGTAS VNLSNVLKNN GGKMENMQLT LNLQTENKGS VVSGGELTIF LDGPTVDLGN VPNGSALTDG SQLPSRDSSG TAVAPENRHQ PPSTNCFGGR SRTHRHSGAS ARTTPATGEQ SPGARSRHRQ PVKNSGHSGL ANGTVNDEPT TATDPEEPSV VGVTSPPAAP LSVTPNPNTT SLPAPATPAE GEEPSTSGTQ QLPAAAQAPD ALPAGWEQRE LPNGRVYYVD HNTKTTTWER PLPPGWEKRT DPRGRFYYVD HNTRTTTWQR PTAEYVRNYE QWQSQRNQLQ GAMQHFSQRF LYQSSSASTD HDPLGPLPPG WEKRQDNGRV YYVNHNTRTT QWEDPRTQGM IQEPALPPGW EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH QFRFLCHSNA LPSHVKISVS RQTLFEDSFQ QIMNMKPYDL RRRLYIIMRG EEGLDYGGIA REWFFLLSHE VLNPMYCLFE YAGKNNYCLQ INPASSINPD HLTYFRFIGR FIAMALYHGK FIDTGFTLPF YKRMLNKRPT LKDLESIDPE FYNSIVWIKE NNLEECGLEL YFIQDMEILG KVTTHELKEG GESIRVTEEN KEEYIMLLTD WRFTRGVEEQ TKAFLDGFNE VAPLEWLRYF DEKELELMLC GMQEIDMSDW QKSTIYRHYT KNSKQIQWFW QVVKEMDNEK RIRLLQFVTG TCRLPVGGFA ELIGSNGPQK FCIDKVGKET WLPRSHTCFN RLDLPPYKSY EQLREKLLYA IEETEGFGQE
Genular Protein ID: 3666920049
Symbol: B4DHF6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 488
- Mass: 57781
- Checksum: AA073578DF0D4E1F
- Sequence:
MQHFSQRFLY QSSSASTDHD PLGPLPPGWE KRQDNGRVYY VNHNTRTTQW EDPRTQGMIQ EPALPPGWEM KYTSEGVRYF VDHNTRTTTF KDPRPGFESG TKQGSPGAYD RSFRWKYHQF RFLCHSNALP SHVKISVSRQ TLFEDSFQQI MNMKPYDLRR RLYIIMRGEE GLDYGGIARE WFFLLSHEVL NPMYCLFEYA GKNNYCLQIN PASSINPDHL TYFRFIGRFI AMALYHGKFI DTGFTLPFYK RMLNKRPTLK DLESIDPEFY NSIVWIKENN LEECGLELYF IQDMEILGKV TTHELKEGGE SIRVTEENKE EYIMLLTDWR FTRGVEEQTK AFLDGFNEVA PLEWLRYFDE KELELMLCGM QEIDMSDWQK STIYRHYTKN SKQIQWFWQV VKEMDNEKRI RLLQFVTGTC RLPVGGFAEL IGSNGPQKFC IDKVGKETWL PRSHTCFNRL DLPPYKSYEQ LREKLLYAIE ETEGFGQE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.