Details for: CHD3

Gene ID: 1107

Symbol: CHD3

Ensembl ID: ENSG00000170004

Description: chromodomain helicase DNA binding protein 3

Associated with

Other Information

Genular Protein ID: 4018974379

Symbol: CHD3_HUMAN

Name: Chromodomain-helicase-DNA-binding protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9688266

Title: Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family.

PubMed ID: 9688266

DOI: 10.1046/j.1432-1327.1998.2540558.x

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 9326634

Title: Characterization of the CHD family of proteins.

PubMed ID: 9326634

DOI: 10.1073/pnas.94.21.11472

PubMed ID: 7560064

Title: Molecular analysis of a major antigenic region of the 240 kD protein of Mi-2 autoantigen.

PubMed ID: 7560064

DOI: 10.1172/jci118218

PubMed ID: 9804427

Title: Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.

PubMed ID: 9804427

DOI: 10.1038/27699

PubMed ID: 11230151

Title: Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.

PubMed ID: 11230151

DOI: 10.1101/gad.869501

PubMed ID: 14609633

Title: Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules.

PubMed ID: 14609633

DOI: 10.1016/j.virusres.2003.09.001

PubMed ID: 12505151

Title: Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3.

PubMed ID: 12505151

DOI: 10.1016/s0014-5793(02)03737-7

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16428440

Title: MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

PubMed ID: 16428440

DOI: 10.1128/mcb.26.3.843-851.2006

PubMed ID: 17626165

Title: Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.

PubMed ID: 17626165

DOI: 10.1091/mbc.e06-07-0604

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 27068747

Title: Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2alpha.

PubMed ID: 27068747

DOI: 10.1074/jbc.m115.713370

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28977666

Title: CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

PubMed ID: 28977666

DOI: 10.1093/nar/gkx711

PubMed ID: 33283408

Title: Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

PubMed ID: 33283408

DOI: 10.1111/febs.15650

PubMed ID: 29463886

Title: A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development.

PubMed ID: 29463886

DOI: 10.1038/s41380-018-0020-x

PubMed ID: 30397230

Title: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

PubMed ID: 30397230

DOI: 10.1038/s41467-018-06014-6

Sequence Information:

  • Length: 2000
  • Mass: 226592
  • Checksum: 4494F56E5D0E7083
  • Sequence:
  • MKAADTVILW ARSKNDQLRI SFPPGLCWGD RMPDKDDIRL LPSALGVKKR KRGPKKQKEN 
    KPGKPRKRKK RDSEEEFGSE RDEYREKSES GGSEYGTGPG RKRRRKHREK KEKKTKRRKK 
    GEGDGGQKQV EQKSSATLLL TWGLEDVEHV FSEEDYHTLT NYKAFSQFMR PLIAKKNPKI 
    PMSKMMTILG AKWREFSANN PFKGSAAAVA AAAAAAAAAV AEQVSAAVSS ATPIAPSGPP 
    ALPPPPAADI QPPPIRRAKT KEGKGPGHKR RSKSPRVPDG RKKLRGKKMA PLKIKLGLLG 
    GKRKKGGSYV FQSDEGPEPE AEESDLDSGS VHSASGRPDG PVRTKKLKRG RPGRKKKKVL 
    GCPAVAGEEE VDGYETDHQD YCEVCQQGGE IILCDTCPRA YHLVCLDPEL DRAPEGKWSC 
    PHCEKEGVQW EAKEEEEEYE EEGEEEGEKE EEDDHMEYCR VCKDGGELLC CDACISSYHI 
    HCLNPPLPDI PNGEWLCPRC TCPVLKGRVQ KILHWRWGEP PVAVPAPQQA DGNPDVPPPR 
    PLQGRSEREF FVKWVGLSYW HCSWAKELQL EIFHLVMYRN YQRKNDMDEP PPLDYGSGED 
    DGKSDKRKVK DPHYAEMEEK YYRFGIKPEW MTVHRIINHS VDKKGNYHYL VKWRDLPYDQ 
    STWEEDEMNI PEYEEHKQSY WRHRELIMGE DPAQPRKYKK KKKELQGDGP PSSPTNDPTV 
    KYETQPRFIT ATGGTLHMYQ LEGLNWLRFS WAQGTDTILA DEMGLGKTIQ TIVFLYSLYK 
    EGHTKGPFLV SAPLSTIINW EREFQMWAPK FYVVTYTGDK DSRAIIRENE FSFEDNAIKG 
    GKKAFKMKRE AQVKFHVLLT SYELITIDQA ALGSIRWACL VVDEAHRLKN NQSKFFRVLN 
    GYKIDHKLLL TGTPLQNNLE ELFHLLNFLT PERFNNLEGF LEEFADISKE DQIKKLHDLL 
    GPHMLRRLKA DVFKNMPAKT ELIVRVELSP MQKKYYKYIL TRNFEALNSR GGGNQVSLLN 
    IMMDLKKCCN HPYLFPVAAM ESPKLPSGAY EGGALIKSSG KLMLLQKMLR KLKEQGHRVL 
    IFSQMTKMLD LLEDFLDYEG YKYERIDGGI TGALRQEAID RFNAPGAQQF CFLLSTRAGG 
    LGINLATADT VIIFDSDWNP HNDIQAFSRA HRIGQANKVM IYRFVTRASV EERITQVAKR 
    KMMLTHLVVR PGLGSKAGSM SKQELDDILK FGTEELFKDE NEGENKEEDS SVIHYDNEAI 
    ARLLDRNQDA TEDTDVQNMN EYLSSFKVAQ YVVREEDKIE EIEREIIKQE ENVDPDYWEK 
    LLRHHYEQQQ EDLARNLGKG KRVRKQVNYN DAAQEDQDNQ SEYSVGSEEE DEDFDERPEG 
    RRQSKRQLRN EKDKPLPPLL ARVGGNIEVL GFNTRQRKAF LNAVMRWGMP PQDAFTTQWL 
    VRDLRGKTEK EFKAYVSLFM RHLCEPGADG SETFADGVPR EGLSRQQVLT RIGVMSLVKK 
    KVQEFEHING RWSMPELMPD PSADSKRSSR ASSPTKTSPT TPEASATNSP CTSKPATPAP 
    SEKGEGIRTP LEKEEAENQE EKPEKNSRIG EKMETEADAP SPAPSLGERL EPRKIPLEDE 
    VPGVPGEMEP EPGYRGDREK SATESTPGER GEEKPLDGQE HRERPEGETG DLGKREDVKG 
    DRELRPGPRD EPRSNGRREE KTEKPRFMFN IADGGFTELH TLWQNEERAA ISSGKLNEIW 
    HRRHDYWLLA GIVLHGYARW QDIQNDAQFA IINEPFKTEA NKGNFLEMKN KFLARRFKLL 
    EQALVIEEQL RRAAYLNLSQ EPAHPAMALH ARFAEAECLA ESHQHLSKES LAGNKPANAV 
    LHKVLNQLEE LLSDMKADVT RLPATLSRIP PIAARLQMSE RSILSRLASK GTEPHPTPAY 
    PPGPYATPPG YGAAFSAAPV GALAAAGANY SQMPAGSFIT AATNGPPVLV KKEKEMVGAL 
    VSDGLDRKEP RAGEVICIDD

Genular Protein ID: 1823138143

Symbol: Q2TAZ1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 661
  • Mass: 73526
  • Checksum: 61B9D39D2DC3B33C
  • Sequence:
  • GKRVRKQVNY NDAAQEDQDN QSEYSVGSEE EDEDFDERPE GRRQSKRQLR NEKDKPLPPL 
    LARVGGNIEV LGFNTRQRKA FLNAVMRWGM PPQDAFTTQW LVRDLRGKTE KEFKAYVSLF 
    MRHLCEPGAD GSETFADGVP REGLSRQQVL TRIGVMSLVK KKVQEFEHIN GRWSMPELMP 
    DPSADSKRSS RASSPTKTSP TTPEASATNS PCTSKPATPA PSEKGEGIRT PLEKEEAENQ 
    EEKPEKNSRI GEKMETEADA PSPAPSLGER LEPRKIPLED EVPGVPGEME PEPGYRGDRE 
    KSATESTPGE RGEEKPLDGQ EHRERPEGET GDLGKREDVK GDRELRPGPR DEPRSNGRRE 
    EKTEKPRFMF NIADGGFTEL HTLWQNEERA AISSGKLNEI WHRRHDYWLL AGIVLHGYAR 
    WQDIQNDAQF AIINEPFKTE ANKGNFLEMK NKFLARRFKL LEQALVIEEQ LRRAAYLNLS 
    QEPAHPAMAL HARFAEAECL AESHQHLSKE SLAGNKPANA VLHKVLNQLE ELLSDMKADV 
    TRLPATLSRI PPIAARLQMS ERSILSRLAS KGTEPHPTPA YPPGPYATPP GYGAAFSAAP 
    VGALAAAGAN YSQMPAGSFI TAATNGPPVL VKKEKEMVGA LVSDGLDRKE PRAGEVICID 
    D

Genular Protein ID: 802007798

Symbol: B3KWV4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 577
  • Mass: 63784
  • Checksum: 23EACA99690835BE
  • Sequence:
  • MRWGMPPQDA FTTQWLVRDL RGKTEKEFKA YVSLFMRHLC EPGADGSETF ADGVPREGLS 
    RQQVLTRIGV MSLVKKKVQE FEHINGRWSM PELMPDPSAD SKRSSRASSP TKTSPTTPEA 
    SATNSPCTSK PATPAPSEKG EGIRTPLEKE EAENQEEKPE KNSRIGEKME TEADAPSPAP 
    SLGERLEPRK IPLEDEVPGV PGEMEPEPGY RGDREKSATE STPGERGEEK PLDGQEHRER 
    PEGETGDLGK RAEDVKGDRE LRPGPRDEPR SNGRREEKTE KPRFMFNIAD GGFTELHTLW 
    QNEERAAISS GKLNEIWHRR HDYWLLAGIV LHGYARWQDI QNDAQFAIIN EPFKTEANKG 
    NFLEMKNKFL ARRFKLLEQA LVIEEQLRRA AYLNLSQEPA HPAMALHARF AEAECLAESH 
    QHLSKESLAG NKPANAVLHK VLNQLEELLS DMKADVTRLP ATLSRIPPIA ARLQMSERSI 
    LSRLASKGTE PHPTPAYPPG PYATPPGYGA AFSAAPVGAL AAAGANYSQM PAGSFITAAT 
    NGPPVLVKKE KEMVGALVSD GLDRKEPRAG EVICIDD

Genular Protein ID: 2132719813

Symbol: A0A8V8TR54_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 2114
  • Mass: 238543
  • Checksum: E9CAA6DDB4FC3A24
  • Sequence:
  • MASPLRDEEE EEEEMVVSEE EEEEEEEGDE EEEEEVEAAD EDDEEDDDEG VLGRGPGHDR 
    GRDRHSPPGC HLFPPPPPPP PPLPPPPPPP PPDKDDIRLL PSALGVKKRK RGPKKQKENK 
    PGKPRKRKKR DSEEEFGSER DEYREKSESG GSEYGTGPGR KRRRKHREKK EKKTKRRKKG 
    EGDGGQKQVE QKSSATLLLT WGLEDVEHVF SEEDYHTLTN YKAFSQFMRP LIAKKNPKIP 
    MSKMMTILGA KWREFSANNP FKGSAAAVAA AAAAAAAAVA EQVSAAVSSA TPIAPSGPPA 
    LPPPPAADIQ PPPIRRAKTK EGKGPGHKRR SKSPRVPDGR KKLRGKKMAP LKIKLGLLGG 
    KRKKGGSYVF QSDEGPEPEA EESDLDSGSV HSASGRPDGP VRTKKLKRGR PGRKKKKVLG 
    CPAVAGEEEV DGYETDHQDY CEVCQQGGEI ILCDTCPRAY HLVCLDPELD RAPEGKWSCP 
    HCEKEGVQWE AKEEEEEYEE EGEEEGEKEE EDDHMEYCRV CKDGGELLCC DACISSYHIH 
    CLNPPLPDIP NGEWLCPRCT CPVLKGRVQK ILHWRWGEPP VAVPAPQQAD GNPDVPPPRP 
    LQGRSEREFF VKWVGLSYWH CSWAKELQLE IFHLVMYRNY QRKNDMDEPP PLDYGSGEDD 
    GKSDKRKVKD PHYAEMEEKY YRFGIKPEWM TVHRIINHSV DKKGNYHYLV KWRDLPYDQS 
    TWEEDEMNIP EYEEHKQSYW RHRELIMGED PAQPRKYKKK KKELQGDGPP SSPTNDPTVK 
    YETQPRFITA TGGTLHMYQL EGLNWLRFSW AQGTDTILAD EMGLGKTIQT IVFLYSLYKE 
    GHTKGPFLVS APLSTIINWE REFQMWAPKF YVVTYTGDKD SRAIIRENEF SFEDNAIKGG 
    KKAFKMKREA QVKFHVLLTS YELITIDQAA LGSIRWACLV VDEAHRLKNN QSKFFRVLNG 
    YKIDHKLLLT GTPLQNNLEE LFHLLNFLTP ERFNNLEGFL EEFADISKED QIKKLHDLLG 
    PHMLRRLKAD VFKNMPAKTE LIVRVELSPM QKKYYKYILT RNFEALNSRG GGNQVSLLNI 
    MMDLKKCCNH PYLFPVAAME SPKLPSGAYE GGALIKSSGK LMLLQKMLRK LKEQGHRVLI 
    FSQMTKMLDL LEDFLDYEGY KYERIDGGIT GALRQEAIDR FNAPGAQQFC FLLSTRAGGL 
    GINLATADTV IIFDSDWNPH NDIQAFSRAH RIGQANKVMI YRFVTRASVE ERITQVAKRK 
    MMLTHLVVRP GLGSKAGSMS KQELDDILKF GTEELFKDEN EGENKEEDSS VIHYDNEAIA 
    RLLDRNQDAT EDTDVQNMNE YLSSFKVAQY VVREEDKIEE IEREIIKQEE NVDPDYWEKL 
    LRHHYEQQQE DLARNLGKGK RVRKQVNYND AAQEDQDNQS EYSVGSEEED EDFDERPEGR 
    RQSKRQLRNE KDKPLPPLLA RVGGNIEVLG FNTRQRKAFL NAVMRWGMPP QDAFTTQWLV 
    RDLRGKTEKE FKAYVSLFMR HLCEPGADGS ETFADGVPRE GLSRQQVLTR IGVMSLVKKK 
    VQEFEHINGR WSMPELMPDP SADSKRSSRA SSPTKTSPTT PEASATNSPC TSKPATPAPS 
    EKGEGIRTPL EKEEAENQEE KPEKNSRIGE KMETEADAPS PAPSLGERLE PRKIPLEDEV 
    PGVPGEMEPE PGYRGDREKS ATESTPGERG EEKPLDGQEH RERPEGETGD LGKREDVKGD 
    RELRPGPRDE PRSNGRREEK TEKPRFMFNI ADGGFTELHT LWQNEERAAI SSGKLNEIWH 
    RRHDYWLLAG IVLHGYARWQ DIQNDAQFAI INEPFKTEAN KGNFLEMKNK FLARRFKLLE 
    QALVIEEQLR RAAYLNLSQE PAHPAMALHA RFAEAECLAE SHQHLSKESL AGNKPANAVL 
    HKGKGRGGPA RGRAHNAASE PAGGVAERHE GGRDPPASHA VPNTPHRSPP SDVRAQHPQP 
    AGQQGHGASP HTGLPAGSLR YTSGVRGGLQ RRTRRGPGRR RRQLQPDACR VLHHSRHQRP 
    SSACEEGEGN GGGIGVRRAG SEGAPSRGGD LYRRLTGSQA CPSPRPRPRG RPPAQALGPA 
    ASPPPSPPLG PSLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.