FAF1 | ENSG00000185104 | NCBI 11124

Details for: FAF1

Gene ID: 11124

Symbol: FAF1

Ensembl ID: ENSG00000185104

Description: Fas associated factor 1

Associated with

Apoptotic process
(GO:0006915)
Cd95 death-inducing signaling complex
(GO:0031265)
Cytoplasmic sequestering of nf-kappab
(GO:0007253)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Erad pathway
(GO:0036503)
Heat shock protein binding
(GO:0031072)
Nf-kappab binding
(GO:0051059)
Nuclear envelope
(GO:0005635)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Ooplasm
(GO:1990917)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of dna replication
(GO:0045740)
Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
(GO:1902043)
Positive regulation of protein-containing complex assembly
(GO:0031334)
Positive regulation of protein catabolic process
(GO:0045732)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase binding
(GO:0019901)
Protein kinase regulator activity
(GO:0019887)
Regulation of cell adhesion
(GO:0030155)
Regulation of protein catabolic process
(GO:0042176)
Ubiquitin binding
(GO:0043130)
Ubiquitin protein ligase binding
(GO:0031625)
Vcp-npl4-ufd1 aaa atpase complex
(GO:0034098)

Other Information

Proteins

FAS-associated factor 1

Genular Protein ID: 567817011

Symbol: FAF1_HUMAN

Name: FAS-associated factor 1

UniProtKB Accession Codes:

Q9UNN5 Q549F0 Q9UF34 Q9UNT3 Q9Y2Z3

Database IDs:

Citations:

PubMed ID: 10462485

Title: Identification and characterization of human Fas associated factor 1, hFAF1.

PubMed ID: 10462485

DOI: 10.1006/bbrc.1999.1217

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21978668

Title: The NLRP12 pyrin domain: structure, dynamics, and functional insights.

PubMed ID: 21978668

DOI: 10.1016/j.jmb.2011.09.024

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26842564

Title: Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.

PubMed ID: 26842564

DOI: 10.1038/ncomms10612

PubMed ID: 11243799

Title: The UBX domain: a widespread ubiquitin-like module.

PubMed ID: 11243799

DOI: 10.1006/jmbi.2000.4462

PubMed ID: 19722279

Title: Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1.

PubMed ID: 19722279

DOI: 10.1002/pro.237

Sequence Information:

Length: 650
Mass: 73954
Checksum: 7FB9018B9A230488
Sequence:

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGGET 
IPGPAFNPAS HPASAPTSSS SSAFRPVMPS RQIVERQPRM LDFRVEYRDR NVDVVLEDTC 
TVGEIKQILE NELQIPVSKM LLKGWKTGDV EDSTVLKSLH LPKNNSLYVL TPDLPPPSSS 
SHAGALQESL NQNFMLIITH REVQREYNLN FSGSSTIQEV KRNVYDLTSI PVRHQLWEGW 
PTSATDDSMC LAESGLSYPC HRLTVGRRSS PAQTREQSEE QITDVHMVSD SDGDDFEDAT 
EFGVDDGEVF GMASSALRKS PMMPENAENE GDALLQFTAE FSSRYGDCHP VFFIGSLEAA 
FQEAFYVKAR DRKLLAIYLH HDESVLTNVF CSQMLCAESI VSYLSQNFIT WAWDLTKDSN 
RARFLTMCNR HFGSVVAQTI RTQKTDQFPL FLIIMGKRSS NEVLNVIQGN TTVDELMMRL 
MAAMEIFTAQ QQEDIKDEDE REARENVKRE QDEAYRLSLE ADRAKREAHE REMAEQFRLE 
QIRKEQEEER EAIRLSLEQA LPPEPKEENA EPVSKLRIRT PSGEFLERRF LASNKLQIVF 
DFVASKGFPW DEYKLLSTFP RRDVTQLDPN KSLLEVKLFP QETLFLEAKE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FAF1

Associated with

Other Information

Identification and characterization of human Fas associated factor 1, hFAF1. PubMed ID: 10462485

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. PubMed ID: 10810093

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

The NLRP12 pyrin domain: structure, dynamics, and functional insights. PubMed ID: 21978668

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. PubMed ID: 26842564

The UBX domain: a widespread ubiquitin-like module. PubMed ID: 11243799

Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1. PubMed ID: 19722279