Details for: CHGA

Gene ID: 1113

Symbol: CHGA

Ensembl ID: ENSG00000100604

Description: chromogranin A

Associated with

Other Information

Genular Protein ID: 2056518800

Symbol: CMGA_HUMAN

Name: Chromogranin-A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2445752

Title: The primary structure of human chromogranin A and pancreastatin.

PubMed ID: 2445752

DOI: 10.1016/s0021-9258(18)45486-5

PubMed ID: 3403545

Title: Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA.

PubMed ID: 3403545

DOI: 10.1016/s0021-9258(18)37995-x

PubMed ID: 8120054

Title: Human chromogranin A gene. Molecular cloning, structural analysis, and neuroendocrine cell-specific expression.

PubMed ID: 8120054

DOI: 10.1016/s0021-9258(17)37462-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3704195

Title: Chromogranin from normal human adrenal glands: purification by monoclonal antibody affinity chromatography and partial N-terminal amino acid sequence.

PubMed ID: 3704195

DOI: 10.1016/0167-0115(86)90040-6

PubMed ID: 2165909

Title: Isolation and characterization of a tumor-derived human protein related to chromogranin A and its in vitro conversion to human pancreastatin-48.

PubMed ID: 2165909

DOI: 10.1111/j.1432-1033.1990.tb19090.x

PubMed ID: 2830133

Title: Isolation of human pancreastatin fragment containing the active sequence from a glucagonoma.

PubMed ID: 2830133

DOI: 10.1016/0014-5793(88)80606-9

PubMed ID: 1577173

Title: Isolation and primary structure of a novel chromogranin A-derived peptide, WE-14, from a human midgut carcinoid tumour.

PubMed ID: 1577173

DOI: 10.1016/0014-5793(92)80266-j

PubMed ID: 12442257

Title: The spectrum of endogenous human chromogranin A-derived peptides identified using a modified proteomic strategy.

PubMed ID: 12442257

DOI: 10.1002/1615-9861(200211)2:11<1586::aid-prot1586>3.0.co;2-k

PubMed ID: 7535395

Title: Molecular characterization of immunoreactivities of peptides derived from chromogranin A (GE-25) and from secretogranin II (secretoneurin) in human and bovine cerebrospinal fluid.

PubMed ID: 7535395

DOI: 10.1016/0306-4522(94)90582-7

PubMed ID: 9852066

Title: Phosphorylation and O-glycosylation sites of human chromogranin A (CGA79-439) from urine of patients with carcinoid tumors.

PubMed ID: 9852066

DOI: 10.1074/jbc.273.51.34087

PubMed ID: 10781584

Title: Formation of the catecholamine release-inhibitory peptide catestatin from chromogranin A. Determination of proteolytic cleavage sites in hormone storage granules.

PubMed ID: 10781584

DOI: 10.1074/jbc.m001232200

PubMed ID: 14997482

Title: Identification and characterization of phosphorylated proteins in the human pituitary.

PubMed ID: 14997482

DOI: 10.1002/pmic.200300584

PubMed ID: 15723172

Title: New antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A.

PubMed ID: 15723172

DOI: 10.1007/s00018-004-4461-9

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 18541522

Title: Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressure.

PubMed ID: 18541522

DOI: 10.1093/cvr/cvn155

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 20116404

Title: Catestatin: a multifunctional peptide from chromogranin A.

PubMed ID: 20116404

DOI: 10.1016/j.regpep.2010.01.006

PubMed ID: 21214543

Title: Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines.

PubMed ID: 21214543

DOI: 10.1111/j.1365-2567.2010.03395.x

PubMed ID: 23234360

Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.

PubMed ID: 23234360

DOI: 10.1021/pr300963h

PubMed ID: 24723458

Title: Antioxidant properties of a human neuropeptide and its protective effect on free radical-induced DNA damage.

PubMed ID: 24723458

DOI: 10.1002/psc.2634

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25326458

Title: Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.

PubMed ID: 25326458

DOI: 10.1074/mcp.m114.043703

PubMed ID: 37453717

Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.

PubMed ID: 37453717

DOI: 10.1016/j.mcpro.2023.100617

PubMed ID: 14759560

Title: Conformational preferences and activities of peptides from the catecholamine release-inhibitory (catestatin) region of chromogranin A.

PubMed ID: 14759560

DOI: 10.1016/j.regpep.2003.10.035

PubMed ID: 14740315

Title: Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.

PubMed ID: 14740315

DOI: 10.1086/381399

PubMed ID: 15326220

Title: The catecholamine release-inhibitory 'catestatin' fragment of chromogranin a: naturally occurring human variants with different potencies for multiple chromaffin cell nicotinic cholinergic responses.

PubMed ID: 15326220

DOI: 10.1124/mol.104.002139

PubMed ID: 17438154

Title: Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.

PubMed ID: 17438154

DOI: 10.1161/circulationaha.106.628859

PubMed ID: 17991725

Title: Proteolytic cleavage of human chromogranin a containing naturally occurring catestatin variants: differential processing at catestatin region by plasmin.

PubMed ID: 17991725

DOI: 10.1210/en.2007-0838

Sequence Information:

  • Length: 457
  • Mass: 50688
  • Checksum: 2F634E1A83FF0BB1
  • Sequence:
  • MRSAAVLALL LCAGQVTALP VNSPMNKGDT EVMKCIVEVI SDTLSKPSPM PVSQECFETL 
    RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF EDELSEVLEN QSSQAELKEA 
    VEEPSSKDVM EKREDSKEAE KSGEATDGAR PQALPEPMQE SKAEGNNQAP GEEEEEEEEA 
    TNTHPPASLP SQKYPGPQAE GDSEGLSQGL VDREKGLSAE PGWQAKREEE EEEEEEAEAG 
    EEAVPEEEGP TVVLNPHPSL GYKEIRKGES RSEALAVDGA GKPGAEEAQD PEGKGEQEHS 
    QQKEEEEEMA VVPQGLFRGG KSGELEQEEE RLSKEWEDSK RWSKMDQLAK ELTAEKRLEG 
    QEEEEDNRDS SMKLSFRARA YGFRGPGPQL RRGWRPSSRE DSLEAGLPLQ VRGYPEEKKE 
    EEGSANRRPE DQELESLSAI EAELEKVAHQ LQALRRG

Genular Protein ID: 3531950971

Symbol: G5E968_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 306
  • Mass: 34269
  • Checksum: C3B1FE96C770678D
  • Sequence:
  • MRSAAVLALL LCAGQVTALP VNSPMNKGDT EVMKCIVEVI SDTLSKPSPM PVSQECFETL 
    RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF EDELSEVLEN QSSQAELKGR 
    SEALAVDGAG KPGAEEAQDP EGKGEQEHSQ QKEEEEEMAV VPQGLFRGGK SGELEQEEER 
    LSKEWEDSKR WSKMDQLAKE LTAEKRLEGQ EEEEDNRDSS MKLSFRARAY GFRGPGPQLR 
    RGWRPSSRED SLEAGLPLQV RGYPEEKKEE EGSANRRPED QELESLSAIE AELEKVAHQL 
    QALRRG

Genular Protein ID: 1957959593

Symbol: Q86T07_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 367
  • Mass: 40456
  • Checksum: 86024ED83D2EF724
  • Sequence:
  • EPRAGELAGG STDRRTHAEA LRPQPRAGAT AARPRPPVQP PLARCLGARP HTASCSAPGS 
    AMRSAAVLAL LLCAGQVTAL PVNSPMNKGD TEVMKCIVEV ISDTLSKPSP MPVSQECFET 
    LRGDERILSI LRHQNLLKEL QDLALQGAKE RAHQQKKHSG FEDELSEVLE NQSSQAELKG 
    RSEALAVDGA GKPGAEEAQD PEGKGEQEHS QQKEEEEEMA VVPQGLFRGG KSGELEQEEE 
    RLSKEWEDSK RWSKMDQLAK ELTAEKRLEG QEEEEDNRDS SMKLSFRARA YGFRGPGPQL 
    RRGWRPSSRE DSLEAGLPLQ VRGYPEEKKE EEGSANRRPE DQELESLSAI EAELEKVAHQ 
    LQALRRG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.