Details for: DMC1

Gene ID: 11144

Symbol: DMC1

Ensembl ID: ENSG00000100206

Description: DNA meiotic recombinase 1

Associated with

Other Information

Genular Protein ID: 2053587806

Symbol: DMC1_HUMAN

Name: Meiotic recombination protein DMC1/LIM15 homolog

UniProtKB Accession Codes:

Q14565 A8K9A2 B4DMW6 Q08AI1 Q99498 Q9UH11

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 9 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 EMBL 9 EMDB 4 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 8 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 neXtProt 1

Citations:

PubMed ID: 8590282

Title: Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes.

PubMed ID: 8590282

DOI: 10.1093/dnares/2.4.183

PubMed ID: 8602360

Title: The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.

PubMed ID: 8602360

DOI: 10.1093/nar/24.3.470

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20729832

Title: Purified human BRCA2 stimulates RAD51-mediated recombination.

PubMed ID: 20729832

DOI: 10.1038/nature09399

PubMed ID: 21903585

Title: RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif.

PubMed ID: 21903585

DOI: 10.1074/jbc.m111.290015

PubMed ID: 21307306

Title: Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1).

PubMed ID: 21307306

DOI: 10.1073/pnas.1016454108

PubMed ID: 15125839

Title: Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1.

PubMed ID: 15125839

DOI: 10.1016/s1097-2765(04)00218-7

Sequence Information:

  • Length: 340
  • Mass: 37681
  • Checksum: 040A6E4CF1FEBFA2
  • Sequence:
    • MKEDQVVAEE PGFQDEEESL FQDIDLLQKH GINVADIKKL KSVGICTIKG IQMTTRRALC 
NVKGLSEAKV DKIKEAANKL IEPGFLTAFE YSEKRKMVFH ITTGSQEFDK LLGGGIESMA 
ITEAFGEFRT GKTQLSHTLC VTAQLPGAGG YPGGKIIFID TENTFRPDRL RDIADRFNVD 
HDAVLDNVLY ARAYTSEHQM ELLDYVAAKF HEEAGIFKLL IIDSIMALFR VDFSGRGELA 
ERQQKLAQML SRLQKISEEY NVAVFVTNQM TADPGATMTF QADPKKPIGG HILAHASTTR 
ISLRKGRGEL RIAKIYDSPE MPENEATFAI TAGGIGDAKE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.