CORO1A | ENSG00000102879 | NCBI 11151

Details for: CORO1A

Gene ID: 11151

Symbol: CORO1A

Ensembl ID: ENSG00000102879

Description: coronin 1A

Associated with

Bacterial infection pathways
(R-HSA-9824439)
Disease
(R-HSA-1643685)
Infection with mycobacterium tuberculosis
(R-HSA-9635486)
Infectious disease
(R-HSA-5663205)
Prevention of phagosomal-lysosomal fusion
(R-HSA-9636383)
Response of mtb to phagocytosis
(R-HSA-9637690)
Suppression of phagosomal maturation
(R-HSA-9637687)
Actin binding
(GO:0003779)
Actin cytoskeleton organization
(GO:0030036)
Actin filament
(GO:0005884)
Actin filament binding
(GO:0051015)
Actin filament organization
(GO:0007015)
Actin monomer binding
(GO:0003785)
Axon
(GO:0030424)
Calcium ion transport
(GO:0006816)
Cell-cell junction
(GO:0005911)
Cell-substrate adhesion
(GO:0031589)
Cell migration
(GO:0016477)
Cellular response to interleukin-4
(GO:0071353)
Cortical actin cytoskeleton
(GO:0030864)
Cytoplasm
(GO:0005737)
Cytoskeletal protein binding
(GO:0008092)
Cytosol
(GO:0005829)
Early endosome
(GO:0005769)
Early endosome to recycling endosome transport
(GO:0061502)
Epithelial cell migration
(GO:0010631)
Extracellular exosome
(GO:0070062)
Glutamatergic synapse
(GO:0098978)
Homeostasis of number of cells within a tissue
(GO:0048873)
Immunological synapse
(GO:0001772)
Immunological synapse formation
(GO:0001771)
Innate immune response
(GO:0045087)
Lamellipodium
(GO:0030027)
Leukocyte chemotaxis
(GO:0030595)
Membrane
(GO:0016020)
Myosin heavy chain binding
(GO:0032036)
Natural killer cell degranulation
(GO:0043320)
Negative regulation of actin nucleation
(GO:0051126)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of vesicle fusion
(GO:0031339)
Nerve growth factor signaling pathway
(GO:0038180)
Neuron apoptotic process
(GO:0051402)
Nucleus
(GO:0005634)
Phagocytic cup
(GO:0001891)
Phagocytic vesicle
(GO:0045335)
Phagocytic vesicle membrane
(GO:0030670)
Phagocytosis
(GO:0006909)
Phagolysosome assembly
(GO:0001845)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Plasma membrane
(GO:0005886)
Positive chemotaxis
(GO:0050918)
Positive regulation of t cell migration
(GO:2000406)
Positive regulation of t cell proliferation
(GO:0042102)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of actin filament polymerization
(GO:0030833)
Regulation of cell shape
(GO:0008360)
Regulation of release of sequestered calcium ion into cytosol
(GO:0051279)
Rna binding
(GO:0003723)
T cell homeostasis
(GO:0043029)
T cell proliferation
(GO:0042098)
Thymocyte migration
(GO:0072679)
Uropod organization
(GO:0032796)
Vesicle fusion
(GO:0006906)

Other Information

Proteins

Coronin-1A

Genular Protein ID: 4196003433

Symbol: COR1A_HUMAN

Name: Coronin-1A

UniProtKB Accession Codes:

P31146 B2RBL1 Q2YD73

Database IDs:

Citations:

PubMed ID: 7758584

Title: Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif.

PubMed ID: 7758584

DOI: 10.1016/0014-5793(95)00393-n

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1286667

Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.

PubMed ID: 1286667

DOI: 10.1002/elps.11501301199

PubMed ID: 10338208

Title: A coat protein on phagosomes involved in the intracellular survival of mycobacteria.

PubMed ID: 10338208

DOI: 10.1016/s0092-8674(00)80754-0

PubMed ID: 19097825

Title: Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion.

PubMed ID: 19097825

DOI: 10.1016/j.clim.2008.11.002

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22016387

Title: GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A.

PubMed ID: 22016387

DOI: 10.1074/jbc.m111.222711

PubMed ID: 23100250

Title: Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin.

PubMed ID: 23100250

DOI: 10.1074/jbc.m112.349829

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 23522482

Title: Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation.

PubMed ID: 23522482

DOI: 10.1016/j.jaci.2013.01.042

Sequence Information:

Length: 461
Mass: 51026
Checksum: DE3FEDA57041515E
Sequence:

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI CEASGGGAFL 
VLPLGKTGRV DKNAPTVCGH TAPVLDIAWC PHNDNVIASG SEDCTVMVWE IPDGGLMLPL 
REPVVTLEGH TKRVGIVAWH TTAQNVLLSA GCDNVIMVWD VGTGAAMLTL GPEVHPDTIY 
SVDWSRDGGL ICTSCRDKRV RIIEPRKGTV VAEKDRPHEG TRPVRAVFVS EGKILTTGFS 
RMSERQVALW DTKHLEEPLS LQELDTSSGV LLPFFDPDTN IVYLCGKGDS SIRYFEITSE 
APFLHYLSMF SSKESQRGMG YMPKRGLEVN KCEIARFYKL HERRCEPIAM TVPRKSDLFQ 
EDLYPPTAGP DPALTAEEWL GGRDAGPLLI SLKDGYVPPK SRELRVNRGL DTGRRRAAPE 
ASGTPSSDAV SRLEEEMRKL QATVQELQKR LDRLEETVQA K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CORO1A

Associated with

Other Information

Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif. PubMed ID: 7758584

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. PubMed ID: 1286667

A coat protein on phagosomes involved in the intracellular survival of mycobacteria. PubMed ID: 10338208

Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion. PubMed ID: 19097825

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A. PubMed ID: 22016387

Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin. PubMed ID: 23100250

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation. PubMed ID: 23522482