Details for: PTP4A3

Gene ID: 11156

Symbol: PTP4A3

Ensembl ID: ENSG00000184489

Description: protein tyrosine phosphatase 4A3

Associated with

Other Information

Genular Protein ID: 3348333201

Symbol: TP4A3_HUMAN

Name: Protein tyrosine phosphatase type IVA 3

UniProtKB Accession Codes:

O75365 Q8IVN5 Q99849 Q9BTW5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DEPOD 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 2 EMBL 5 EPD 1 Ensembl 16 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 4 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 6 Rhea 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9633825

Title: Multiple phosphotyrosine phosphatase mRNAs are expressed in the human lung fibroblast cell line WI-38.

PubMed ID: 9633825

PubMed ID: 11355880

Title: Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling.

PubMed ID: 11355880

DOI: 10.1006/bbrc.2001.4881

PubMed ID: 11598267

Title: A phosphatase associated with metastasis of colorectal cancer.

PubMed ID: 11598267

DOI: 10.1126/science.1065817

PubMed ID: 12235145

Title: The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis.

PubMed ID: 12235145

DOI: 10.1074/jbc.m206407200

PubMed ID: 12516958

Title: Pentamidine is an inhibitor of PRL phosphatases with anticancer activity.

PubMed ID: 12516958

PubMed ID: 12782572

Title: PRL-3 and PRL-1 promote cell migration, invasion, and metastasis.

PubMed ID: 12782572

PubMed ID: 15135076

Title: Structure of human PRL-3, the phosphatase associated with cancer metastasis.

PubMed ID: 15135076

DOI: 10.1016/j.febslet.2004.03.062

PubMed ID: 14704153

Title: Structural insights into molecular function of the metastasis-associated phosphatase PRL-3.

PubMed ID: 14704153

DOI: 10.1074/jbc.m312905200

Sequence Information:

  • Length: 173
  • Mass: 19535
  • Checksum: 15DF01999A9A3573
  • Sequence:
    • MARMNRPAPV EVSYKHMRFL ITHNPTNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK 
DGITVVDWPF DDGAPPPGKV VEDWLSLVKA KFCEAPGSCV AVHCVAGLGR APVLVALALI 
ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF KDPHTHKTRC CVM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.