FSTL1 | ENSG00000163430 | NCBI 11167

Details for: FSTL1

Gene ID: 11167

Symbol: FSTL1

Ensembl ID: ENSG00000163430

Description: follistatin like 1

Associated with

Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Post-translational protein phosphorylation
(R-HSA-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-HSA-381426)
Signaling by bmp
(R-HSA-201451)
Signaling by tgfb family members
(R-HSA-9006936)
Signal transduction
(R-HSA-162582)
Calcium ion binding
(GO:0005509)
Cell differentiation
(GO:0030154)
Endoplasmic reticulum lumen
(GO:0005788)
Endothelial cell differentiation
(GO:0045446)
Endothelial cell migration
(GO:0043542)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hematopoietic stem cell homeostasis
(GO:0061484)
Heparin binding
(GO:0008201)
Multicellular organism development
(GO:0007275)
Negative regulation of apoptotic process
(GO:0043066)
Protein binding
(GO:0005515)
Regulation of bmp signaling pathway
(GO:0030510)

Other Information

Proteins

Follistatin-related protein 1

Genular Protein ID: 480515202

Symbol: FSTL1_HUMAN

Name: Follistatin-related protein 1

UniProtKB Accession Codes:

Q12841 A8K523 B4DTT5 D3DN90 Q549Z0

Database IDs:

Citations:

PubMed ID: 7957230

Title: Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP). Cloning and sequence of the human homologue.

PubMed ID: 7957230

DOI: 10.1111/j.1432-1033.1994.0937b.x

PubMed ID: 9786430

Title: Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases.

PubMed ID: 9786430

DOI: 10.1093/intimm/10.9.1305

PubMed ID: 15638044

Title: Follistatin-related protein gene (FRP) is expressed in the synovial tissues of rheumatoid arthritis, but its polymorphisms are not associated with genetic susceptibility.

PubMed ID: 15638044

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 20860622

Title: DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-beta superfamily proteins.

PubMed ID: 20860622

DOI: 10.1111/j.1742-4658.2010.07816.x

PubMed ID: 20054002

Title: DIP2A functions as a FSTL1 receptor.

PubMed ID: 20054002

DOI: 10.1074/jbc.m109.069468

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22265692

Title: Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4.

PubMed ID: 22265692

DOI: 10.1016/j.febslet.2012.01.010

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 29212066

Title: Fstl1 Promotes Glioma Growth Through the BMP4/Smad1/5/8 Signaling Pathway.

PubMed ID: 29212066

DOI: 10.1159/000485759

Sequence Information:

Length: 308
Mass: 34986
Checksum: BD4C651FAFF24800
Sequence:

MWKRWLALAL ALVAVAWVRA EEELRSKSKI CANVFCGAGR ECAVTEKGEP TCLCIEQCKP 
HKRPVCGSNG KTYLNHCELH RDACLTGSKI QVDYDGHCKE KKSVSPSASP VVCYQSNRDE 
LRRRIIQWLE AEIIPDGWFS KGSNYSEILD KYFKNFDNGD SRLDSSEFLK FVEQNETAIN 
ITTYPDQENN KLLRGLCVDA LIELSDENAD WKLSFQEFLK CLNPSFNPPE KKCALEDETY 
ADGAETEVDC NRCVCACGNW VCTAMTCDGK NQKGAQTQTE EEMTRYVQEL QKHQETAEKT 
KRVSTKEI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FSTL1

Associated with

Other Information

Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP). Cloning and sequence of the human homologue. PubMed ID: 7957230

Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases. PubMed ID: 9786430

Follistatin-related protein gene (FRP) is expressed in the synovial tissues of rheumatoid arthritis, but its polymorphisms are not associated with genetic susceptibility. PubMed ID: 15638044

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Signal peptide prediction based on analysis of experimentally verified cleavage sites. PubMed ID: 15340161

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-beta superfamily proteins. PubMed ID: 20860622

DIP2A functions as a FSTL1 receptor. PubMed ID: 20054002

Initial characterization of the human central proteome. PubMed ID: 21269460

Follistatin-related protein/follistatin-like 1 evokes an innate immune response via CD14 and toll-like receptor 4. PubMed ID: 22265692

A single kinase generates the majority of the secreted phosphoproteome. PubMed ID: 26091039

Fstl1 Promotes Glioma Growth Through the BMP4/Smad1/5/8 Signaling Pathway. PubMed ID: 29212066