Details for: RASSF1

Gene ID: 11186

Symbol: RASSF1

Ensembl ID: ENSG00000068028

Description: Ras association domain family member 1

Associated with

Other Information

Genular Protein ID: 404652995

Symbol: RASF1_HUMAN

Name: Ras association domain-containing protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10888881

Title: Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

PubMed ID: 10888881

DOI: 10.1038/77083

PubMed ID: 11333291

Title: Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression.

PubMed ID: 11333291

DOI: 10.1093/jnci/93.9.691

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12024041

Title: The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.

PubMed ID: 12024041

DOI: 10.1128/mcb.22.12.4309-4318.2002

PubMed ID: 11857081

Title: The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1.

PubMed ID: 11857081

DOI: 10.1038/sj.onc.1205192

PubMed ID: 14729613

Title: Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.

PubMed ID: 14729613

DOI: 10.1158/0008-5472.can-03-2622

PubMed ID: 15205320

Title: RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics.

PubMed ID: 15205320

DOI: 10.1158/0008-5472.can-04-0267

PubMed ID: 14743218

Title: The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex.

PubMed ID: 14743218

DOI: 10.1038/ncb1091

PubMed ID: 15109305

Title: Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.

PubMed ID: 15109305

DOI: 10.1042/bj20040025

PubMed ID: 15753381

Title: Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5.

PubMed ID: 15753381

DOI: 10.1158/0008-5472.can-04-3896

PubMed ID: 15949439

Title: The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death.

PubMed ID: 15949439

DOI: 10.1016/j.molcel.2005.05.010

PubMed ID: 16510573

Title: Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

PubMed ID: 16510573

DOI: 10.1158/0008-5472.can-05-2951

PubMed ID: 18566590

Title: The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex.

PubMed ID: 18566590

DOI: 10.1038/emboj.2008.115

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 21199877

Title: The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.

PubMed ID: 21199877

DOI: 10.1074/jbc.m110.178210

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 21134643

Title: Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C.

PubMed ID: 21134643

DOI: 10.1016/j.str.2010.09.016

Sequence Information:

  • Length: 344
  • Mass: 39219
  • Checksum: 4071B8D044C1DB2D
  • Sequence:
  • MSGEPELIEL RELAPAGRAG KGRTRLERAN ALRIARGTAC NPTRQLVPGR GHRFQPAGPA 
    THTWCDLCGD FIWGVVRKGL QCARLSADCK FTCHYRCRAL VCLDCCGPRD LGWEPAVERD 
    TNVDEPVEWE TPDLSQAEIE QKIKEYNAQI NSNLFMSLNK DGSYTGFIKV QLKLVRPVSV 
    PSSKKPPSLQ DARRGPGRGT SVRRRTSFYL PKDAVKHLHV LSRTRAREVI EALLRKFLVV 
    DDPRKFALFE RAERHGQVYL RKLLDDEQPL RLRLLAGPSD KALSFVLKEN DSGEVNWDAF 
    SMPELHNFLR ILQREEEEHL RQILQKYSYC RQKIQEALHA CPLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.