ABCB8 | ENSG00000197150 | NCBI 11194

Details for: ABCB8

Gene ID: 11194

Symbol: ABCB8

Ensembl ID: ENSG00000197150

Description: ATP binding cassette subfamily B member 8

Associated with

Abc-family proteins mediated transport
(R-HSA-382556)
Mitochondrial abc transporters
(R-HSA-1369007)
Transport of small molecules
(R-HSA-382551)
Abc-type peptide transporter activity
(GO:0015440)
Atp-binding cassette (abc) transporter complex
(GO:0043190)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell volume homeostasis
(GO:0006884)
Mitochondrial atp-gated potassium channel complex
(GO:0062157)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial membrane
(GO:0031966)
Mitochondrial potassium ion transmembrane transport
(GO:0140141)
Mitochondrion
(GO:0005739)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Peptide transport
(GO:0015833)
Potassium ion transmembrane transport
(GO:0071805)
Protein binding
(GO:0005515)
Transmembrane transport
(GO:0055085)

Other Information

Proteins

MITOS_HUMAN

Genular Protein ID: 1808549608

Symbol: MITOS_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NUT2 A5D8W3 B2RBL8 B3KND2 B4DG02 G3XAP3 O95787 Q53GM0

Database IDs:

Citations:

PubMed ID: 9878413

Title: Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.

PubMed ID: 9878413

DOI: 10.1006/jmbi.1998.2259

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16259955

Title: Targeting of the mitochondrial membrane proteins to the cell surface for functional studies.

PubMed ID: 16259955

DOI: 10.1016/j.bbrc.2005.10.070

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 11829140

Title: Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.

PubMed ID: 11829140

DOI: 10.1007/s10038-002-8653-6

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 21046154

Title: Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8.

PubMed ID: 21046154

DOI: 10.1007/s00438-010-0586-8

PubMed ID: 25063848

Title: PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis.

PubMed ID: 25063848

DOI: 10.1096/fj.14-254045

PubMed ID: 30623799

Title: Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.

PubMed ID: 30623799

DOI: 10.1016/j.isci.2018.12.005

PubMed ID: 31435016

Title: Identification of an ATP-sensitive potassium channel in mitochondria.

PubMed ID: 31435016

DOI: 10.1038/s41586-019-1498-3

Sequence Information:

Length: 735
Mass: 79989
Checksum: B7E02B063E6C6F3B
Sequence:

MLVHLFRVGI RGGPFPGRLL PPLRFQTFSA VRNTWRNGKT GQLHKAEGEY SDGYRSSSLL 
RAVAHLRSQL WAHLPRAPLA PRWSPSAWCW VGGALLGPMV LSKHPHLCLV ALCEAEEAPP 
ASSTPHVVGS RFNWKLFWQF LHPHLLVLGV AVVLALGAAL VNVQIPLLLG QLVEVVAKYT 
RDHVGSFMTE SQNLSTHLLI LYGVQGLLTF GYLVLLSHVG ERMAVDMRRA LFSSLLRQDI 
TFFDANKTGQ LVSRLTTDVQ EFKSSFKLVI SQGLRSCTQV AGCLVSLSML STRLTLLLMV 
ATPALMGVGT LMGSGLRKLS RQCQEQIARA MGVADEALGN VRTVRAFAME QREEERYGAE 
LEACRCRAEE LGRGIALFQG LSNIAFNCMV LGTLFIGGSL VAGQQLTGGD LMSFLVASQT 
VQRSMANLSV LFGQVVRGLS AGARVFEYMA LNPCIPLSGG CCVPKEQLRG SVTFQNVCFS 
YPCRPGFEVL KDFTLTLPPG KIVALVGQSG GGKTTVASLL ERFYDPTAGV VMLDGRDLRT 
LDPSWLRGQV VGFISQEPVL FGTTIMENIR FGKLEASDEE VYTAAREANA HEFITSFPEG 
YNTVVGERGT TLSGGQKQRL AIARALIKQP TVLILDEATS ALDAESERVV QEALDRASAG 
RTVLVIAHRL STVRGAHCIV VMADGRVWEA GTHEELLKKG GLYAELIRRQ ALDAPRTAAP 
PPKKPEGPRS HQHKS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ABCB8

Associated with

Other Information

Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein. PubMed ID: 9878413

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Targeting of the mitochondrial membrane proteins to the cell surface for functional studies. PubMed ID: 16259955

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. PubMed ID: 11829140

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974

Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8. PubMed ID: 21046154

PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis. PubMed ID: 25063848

Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. PubMed ID: 30623799

Identification of an ATP-sensitive potassium channel in mitochondria. PubMed ID: 31435016