Details for: POLI
Associated with
Other Information
Genular Protein ID: 3746991990
Symbol: POLI_HUMAN
Name: DNA polymerase iota
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16177791
Title: DNA sequence and analysis of human chromosome 18.
PubMed ID: 16177791
DOI: 10.1038/nature03983
PubMed ID: 10458907
Title: Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta.
PubMed ID: 10458907
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11013228
Title: Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota.
PubMed ID: 11013228
PubMed ID: 11251121
Title: 5'-deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro.
PubMed ID: 11251121
PubMed ID: 11387224
Title: Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template.
PubMed ID: 11387224
PubMed ID: 12410315
Title: Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.
PubMed ID: 12410315
DOI: 10.1038/nature01117
PubMed ID: 12606586
Title: Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.
PubMed ID: 12606586
DOI: 10.1093/emboj/cdf618
PubMed ID: 14630940
Title: A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair.
PubMed ID: 14630940
DOI: 10.1101/gad.1146103
PubMed ID: 15199127
Title: Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa.
PubMed ID: 15199127
PubMed ID: 15254543
Title: Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.
PubMed ID: 15254543
DOI: 10.1038/nature02692
PubMed ID: 27555320
Title: Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota.
PubMed ID: 27555320
Sequence Information:
- Length: 740
- Mass: 83006
- Checksum: C1A5BF0894E91FDF
- Sequence:
MEKLGVEPEE EGGGDDDEED AEAWAMELAD VGAAASSQGV HDQVLPTPNA SSRVIVHVDL DCFYAQVEMI SNPELKDKPL GVQQKYLVVT CNYEARKLGV KKLMNVRDAK EKCPQLVLVN GEDLTRYREM SYKVTELLEE FSPVVERLGF DENFVDLTEM VEKRLQQLQS DELSAVTVSG HVYNNQSINL LDVLHIRLLV GSQIAAEMRE AMYNQLGLTG CAGVASNKLL AKLVSGVFKP NQQTVLLPES CQHLIHSLNH IKEIPGIGYK TAKCLEALGI NSVRDLQTFS PKILEKELGI SVAQRIQKLS FGEDNSPVIL SGPPQSFSEE DSFKKCSSEV EAKNKIEELL ASLLNRVCQD GRKPHTVRLI IRRYSSEKHY GRESRQCPIP SHVIQKLGTG NYDVMTPMVD ILMKLFRNMV NVKMPFHLTL LSVCFCNLKA LNTAKKGLID YYLMPSLSTT SRSGKHSFKM KDTHMEDFPK DKETNRDFLP SGRIESTRTR ESPLDTTNFS KEKDINEFPL CSLPEGVDQE VFKQLPVDIQ EEILSGKSRE KFQGKGSVSC PLHASRGVLS FFSKKQMQDI PINPRDHLSS SKQVSSVSPC EPGTSGFNSS SSSYMSSQKD YSYYLDNRLK DERISQGPKE PQGFHFTNSN PAVSAFHSFP NLQSEQLFSR NHTTDSHKQT VATDSHEGLT ENREPDSVDE KITFPSDIDP QVFYELPEAV QKELLAEWKR AGSDFHIGHK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.