Details for: CHM

Gene ID: 1121

Symbol: CHM

Ensembl ID: ENSG00000188419

Description: CHM Rab escort protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 304.5738
    Cell Significance Index: -47.3800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 182.1455
    Cell Significance Index: -46.2000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 101.2449
    Cell Significance Index: -47.8000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.9338
    Cell Significance Index: -36.1300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 38.5963
    Cell Significance Index: -47.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.1359
    Cell Significance Index: -36.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.8393
    Cell Significance Index: -45.1100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.1185
    Cell Significance Index: -47.8200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.6785
    Cell Significance Index: -35.8700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.8367
    Cell Significance Index: -19.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0247
    Cell Significance Index: 406.1500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.9784
    Cell Significance Index: 195.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.7216
    Cell Significance Index: 280.0100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.6248
    Cell Significance Index: 1467.0500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5652
    Cell Significance Index: 561.4100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5647
    Cell Significance Index: 310.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.2868
    Cell Significance Index: 79.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.2040
    Cell Significance Index: 67.5600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0979
    Cell Significance Index: 14.9800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.0973
    Cell Significance Index: 13.6100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.0816
    Cell Significance Index: 25.9400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.0784
    Cell Significance Index: 27.7200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.0610
    Cell Significance Index: 71.3400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9312
    Cell Significance Index: 101.2900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8548
    Cell Significance Index: 591.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.8495
    Cell Significance Index: 32.1700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8219
    Cell Significance Index: 36.3600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.7363
    Cell Significance Index: 17.0100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6627
    Cell Significance Index: 34.5200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6305
    Cell Significance Index: 37.8500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6169
    Cell Significance Index: 111.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5298
    Cell Significance Index: 100.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5228
    Cell Significance Index: 40.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.5035
    Cell Significance Index: 11.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4572
    Cell Significance Index: 249.6900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4553
    Cell Significance Index: 55.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4260
    Cell Significance Index: 29.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3505
    Cell Significance Index: 48.1300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3379
    Cell Significance Index: 7.3200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3014
    Cell Significance Index: 13.6600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2711
    Cell Significance Index: 5.8000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2537
    Cell Significance Index: 7.2400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2128
    Cell Significance Index: 5.3200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1860
    Cell Significance Index: 350.2400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1777
    Cell Significance Index: 273.6200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1763
    Cell Significance Index: 3.4400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1742
    Cell Significance Index: 77.0000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1453
    Cell Significance Index: 2.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1364
    Cell Significance Index: 3.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1004
    Cell Significance Index: 63.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0902
    Cell Significance Index: 2.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0869
    Cell Significance Index: 160.2800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0806
    Cell Significance Index: 36.5700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0686
    Cell Significance Index: 93.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0536
    Cell Significance Index: 2.5000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0456
    Cell Significance Index: 5.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0097
    Cell Significance Index: -7.1100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0169
    Cell Significance Index: -0.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0178
    Cell Significance Index: -2.5900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0203
    Cell Significance Index: -15.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0383
    Cell Significance Index: -23.9000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0505
    Cell Significance Index: -38.2000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0545
    Cell Significance Index: -30.7500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0614
    Cell Significance Index: -10.4800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0907
    Cell Significance Index: -4.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0941
    Cell Significance Index: -5.9300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1068
    Cell Significance Index: -2.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1094
    Cell Significance Index: -7.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1103
    Cell Significance Index: -5.7900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1136
    Cell Significance Index: -23.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1154
    Cell Significance Index: -13.2300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1393
    Cell Significance Index: -40.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1412
    Cell Significance Index: -14.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2047
    Cell Significance Index: -24.1400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2166
    Cell Significance Index: -25.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2480
    Cell Significance Index: -17.5400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2798
    Cell Significance Index: -5.9600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2802
    Cell Significance Index: -36.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3068
    Cell Significance Index: -31.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3136
    Cell Significance Index: -14.7400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3279
    Cell Significance Index: -37.4300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4028
    Cell Significance Index: -12.9000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4098
    Cell Significance Index: -30.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4331
    Cell Significance Index: -34.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4682
    Cell Significance Index: -13.4200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.4752
    Cell Significance Index: -3.8800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5048
    Cell Significance Index: -7.2600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5130
    Cell Significance Index: -6.1200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5399
    Cell Significance Index: -11.2000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.5545
    Cell Significance Index: -3.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5627
    Cell Significance Index: -15.3200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6103
    Cell Significance Index: -7.6100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.6684
    Cell Significance Index: -6.1600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.6775
    Cell Significance Index: -23.8100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6882
    Cell Significance Index: -10.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7534
    Cell Significance Index: -26.1800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7762
    Cell Significance Index: -47.5900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7765
    Cell Significance Index: -16.4800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.8074
    Cell Significance Index: -10.1900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8177
    Cell Significance Index: -26.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The CHM gene is a small gene that encodes a protein with a molecular weight of approximately 17 kDa. The protein is highly conserved across species and shares high sequence homology with other RAE1 proteins. The CHM gene is specifically expressed in neurons, where it plays a crucial role in regulating membrane trafficking and protein targeting. The protein is also involved in the regulation of small GTPase-mediated signal transduction, which is essential for various cellular processes, including vesicle-mediated transport and protein geranylgeranylation. **Pathways and Functions** The CHM gene is involved in several key pathways, including: 1. **Intracellular protein transport**: The CHM gene product, RAE1, is involved in the regulation of vesicle-mediated transport, which is essential for the movement of proteins and lipids within cells. 2. **Protein targeting to membrane**: The CHM gene product is involved in the targeting of proteins to specific membranes, which is essential for various cellular processes, including signal transduction and protein geranylgeranylation. 3. **Small GTPase-mediated signal transduction**: The CHM gene product is involved in the regulation of small GTPase-mediated signal transduction, which is essential for various cellular processes, including cell growth, differentiation, and survival. 4. **Protein geranylgeranylation**: The CHM gene product is involved in the geranylgeranylation of small GTPases, which is essential for the activation of these proteins and their subsequent regulation of cellular processes. **Clinical Significance** Dysregulation of the CHM gene has been implicated in various neurodegenerative disorders, including retinitis pigmentosa, a condition characterized by progressive vision loss. Mutations in the CHM gene have been identified in patients with retinitis pigmentosa, and these mutations are associated with impaired Rab geranylgeranylation and subsequent disruption of membrane trafficking. Additionally, the CHM gene has been implicated in other neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease, where dysregulation of membrane trafficking and protein targeting has been observed. In conclusion, the CHM gene plays a crucial role in regulating membrane trafficking and protein targeting in neurons, and dysregulation of this gene has been implicated in various neurodegenerative disorders. Further research is needed to fully understand the mechanisms by which the CHM gene regulates membrane trafficking and protein targeting, and to develop therapeutic strategies to treat these disorders.

Genular Protein ID: 3113907263

Symbol: RAE1_HUMAN

Name: Rab proteins geranylgeranyltransferase component A 1

UniProtKB Accession Codes:

P24386 A1L4D2 O43732

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 2 GO 14 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7981670

Title: Cloning and characterization of the human choroideremia gene.

PubMed ID: 7981670

DOI: 10.1093/hmg/3.7.1041

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1549574

Title: Isolation of a candidate gene for choroideremia.

PubMed ID: 1549574

DOI: 10.1073/pnas.89.6.2135

PubMed ID: 2215697

Title: Cloning of a gene that is rearranged in patients with choroideraemia.

PubMed ID: 2215697

DOI: 10.1038/347674a0

PubMed ID: 1598901

Title: Detection and characterization of point mutations in the choroideremia candidate gene by PCR-SSCP analysis and direct DNA sequencing.

PubMed ID: 1598901

PubMed ID: 1904992

Title: Analysis of choroideraemia gene.

PubMed ID: 1904992

DOI: 10.1038/351614b0

PubMed ID: 7957092

Title: Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.

PubMed ID: 7957092

DOI: 10.1002/j.1460-2075.1994.tb06860.x

PubMed ID: 18532927

Title: Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.

PubMed ID: 18532927

DOI: 10.1042/bj20080662

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21905166

Title: Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with rab geranylgeranyl transferase.

PubMed ID: 21905166

DOI: 10.1002/humu.21591

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26824392

Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

PubMed ID: 26824392

DOI: 10.7554/elife.12813

PubMed ID: 29125462

Title: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

PubMed ID: 29125462

DOI: 10.7554/elife.31012

PubMed ID: 7951216

Title: Missense mutation in the choroideremia gene.

PubMed ID: 7951216

DOI: 10.1093/hmg/3.6.1017

PubMed ID: 19427510

Title: The functional effect of pathogenic mutations in Rab escort protein 1.

PubMed ID: 19427510

DOI: 10.1016/j.mrfmmm.2009.02.015

Sequence Information:

  • Length: 653
  • Mass: 73476
  • Checksum: 7CFFAECE7BA1F3AF
  • Sequence:
    • MADTLPSEFD VIVIGTGLPE SIIAAACSRS GRRVLHVDSR SYYGGNWASF SFSGLLSWLK 
EYQENSDIVS DSPVWQDQIL ENEEAIALSR KDKTIQHVEV FCYASQDLHE DVEEAGALQK 
NHALVTSANS TEAADSAFLP TEDESLSTMS CEMLTEQTPS SDPENALEVN GAEVTGEKEN 
HCDDKTCVPS TSAEDMSENV PIAEDTTEQP KKNRITYSQI IKEGRRFNID LVSKLLYSRG 
LLIDLLIKSN VSRYAEFKNI TRILAFREGR VEQVPCSRAD VFNSKQLTMV EKRMLMKFLT 
FCMEYEKYPD EYKGYEEITF YEYLKTQKLT PNLQYIVMHS IAMTSETASS TIDGLKATKN 
FLHCLGRYGN TPFLFPLYGQ GELPQCFCRM CAVFGGIYCL RHSVQCLVVD KESRKCKAII 
DQFGQRIISE HFLVEDSYFP ENMCSRVQYR QISRAVLITD RSVLKTDSDQ QISILTVPAE 
EPGTFAVRVI ELCSSTMTCM KGTYLVHLTC TSSKTAREDL ESVVQKLFVP YTEMEIENEQ 
VEKPRILWAL YFNMRDSSDI SRSCYNDLPS NVYVCSGPDC GLGNDNAVKQ AETLFQEICP 
NEDFCPPPPN PEDIILDGDS LQPEASESSA IPEANSETFK ESTNLGNLEE SSE

Genular Protein ID: 3829388678

Symbol: B4DRL9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DRL9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 3 IntAct 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 2 PeptideAtlas 1 Pfam 2 ProteomicsDB 1 RefSeq 5 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 505
  • Mass: 57265
  • Checksum: 15F801C543052012
  • Sequence:
    • MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE 
QPKKNRITYS QIIKEGRRFN IDLVSKLLYS RGLLIDLLIK SNVSRYAEFK NITRILAFRE 
GRVEQVPCSR ADVFNSKQLT MVEKRMLMKF LTFCMEYEKY PDEYKGYEEI TFYEYLKTQK 
LTPNLQYIVM HSIAMTSETA SSTIDGLKAT KNFLHCLGRY GNTPFLFPLY GQGELPQCFC 
RMCAVFGGIY CLRHSVQCLV VDKESRKCKA IIDQFGQRII SEHFLVEDSY FPENMCSRVQ 
YRQISRAVLI TDRSVLKTDS DQQISILTVP AEEPGTFAVR VIELCSSTMT CMKGTYLVHL 
TCTSSKTARE DLESVVQKLF VPYTEMEIEN EQVEKPRILW ALYFNMRDSS DISRSCYNDL 
PSNVYVCSGP DCGLGNDNAV KQAETLFQEI CPNEDFCPPP PNPEDIILDG DSLQPEASES 
SAIPEANSET FKESTNLGNL EESSE

Genular Protein ID: 2027369497

Symbol: A8K545_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K545

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 3 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 2 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 1 SUPFAM 2

Sequence Information:

  • Length: 653
  • Mass: 73492
  • Checksum: ED59BECE7E32A271
  • Sequence:
    • MADTLPSEFD VIVIGTGLPE SIIAAACSRS GRRVLHVDSR SYYGGNWASF SFSGLLSWLK 
EYQENSDIVS DSPVWQDQIL ENEEAIALCR KDKTIQHVEV FCYASQDLHE DVEEAGALQK 
NHALVTSANS TEAADSAFLP TEDESLSTMS CEMLTEQTPS SDPENALEVN GAEVTGEKEN 
HCDDKTCVPS TSAEDMSENV PIAEDTTEQP KKNRITYSQI IKEGRRFNID LVSKLLYSRG 
LLIDLLIKSN VSRYAEFKNI TRILAFREGR VEQVPCSRAD VFNSKQLTMV EKRMLMKFLT 
FCMEYEKYPD EYKGYEEITF YEYLKTQKLT PNLQYIVMHS IAMTSETASS TIDGLKATKN 
FLHCLGRYGN TPFLFPLYGQ GELPQCFCRM CAVFGGIYCL RHSVQCLVVD KESRKCKAII 
DQFGQRIISE HFLVEDSYFP ENMCSRVQYR QISRAVLITD RSVLKTDSDQ QISILTVPAE 
EPGTFAVRVI ELCSSTMTCM KGTYLVHLTC TSSKTAREDL ESVVQKLFVP YTEMEIENEQ 
VEKPRILWAL YFNMRDSSDI SRSCYNDLPS NVYVCSGPDC GLGNDNAVKQ AETLFQEICP 
NEDFCPPPPN PEDIILDGDS LQPEASESSA IPEANSETFK ESTNLGNLEE SSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.