Details for: CHM

Gene ID: 1121

Symbol: CHM

Ensembl ID: ENSG00000188419

Description: CHM Rab escort protein

Associated with

Other Information

Genular Protein ID: 3113907263

Symbol: RAE1_HUMAN

Name: Rab proteins geranylgeranyltransferase component A 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7981670

Title: Cloning and characterization of the human choroideremia gene.

PubMed ID: 7981670

DOI: 10.1093/hmg/3.7.1041

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1549574

Title: Isolation of a candidate gene for choroideremia.

PubMed ID: 1549574

DOI: 10.1073/pnas.89.6.2135

PubMed ID: 2215697

Title: Cloning of a gene that is rearranged in patients with choroideraemia.

PubMed ID: 2215697

DOI: 10.1038/347674a0

PubMed ID: 1598901

Title: Detection and characterization of point mutations in the choroideremia candidate gene by PCR-SSCP analysis and direct DNA sequencing.

PubMed ID: 1598901

PubMed ID: 1904992

Title: Analysis of choroideraemia gene.

PubMed ID: 1904992

DOI: 10.1038/351614b0

PubMed ID: 7957092

Title: Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.

PubMed ID: 7957092

DOI: 10.1002/j.1460-2075.1994.tb06860.x

PubMed ID: 18532927

Title: Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.

PubMed ID: 18532927

DOI: 10.1042/bj20080662

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21905166

Title: Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with rab geranylgeranyl transferase.

PubMed ID: 21905166

DOI: 10.1002/humu.21591

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26824392

Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

PubMed ID: 26824392

DOI: 10.7554/elife.12813

PubMed ID: 29125462

Title: Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

PubMed ID: 29125462

DOI: 10.7554/elife.31012

PubMed ID: 7951216

Title: Missense mutation in the choroideremia gene.

PubMed ID: 7951216

DOI: 10.1093/hmg/3.6.1017

PubMed ID: 19427510

Title: The functional effect of pathogenic mutations in Rab escort protein 1.

PubMed ID: 19427510

DOI: 10.1016/j.mrfmmm.2009.02.015

Sequence Information:

  • Length: 653
  • Mass: 73476
  • Checksum: 7CFFAECE7BA1F3AF
  • Sequence:
  • MADTLPSEFD VIVIGTGLPE SIIAAACSRS GRRVLHVDSR SYYGGNWASF SFSGLLSWLK 
    EYQENSDIVS DSPVWQDQIL ENEEAIALSR KDKTIQHVEV FCYASQDLHE DVEEAGALQK 
    NHALVTSANS TEAADSAFLP TEDESLSTMS CEMLTEQTPS SDPENALEVN GAEVTGEKEN 
    HCDDKTCVPS TSAEDMSENV PIAEDTTEQP KKNRITYSQI IKEGRRFNID LVSKLLYSRG 
    LLIDLLIKSN VSRYAEFKNI TRILAFREGR VEQVPCSRAD VFNSKQLTMV EKRMLMKFLT 
    FCMEYEKYPD EYKGYEEITF YEYLKTQKLT PNLQYIVMHS IAMTSETASS TIDGLKATKN 
    FLHCLGRYGN TPFLFPLYGQ GELPQCFCRM CAVFGGIYCL RHSVQCLVVD KESRKCKAII 
    DQFGQRIISE HFLVEDSYFP ENMCSRVQYR QISRAVLITD RSVLKTDSDQ QISILTVPAE 
    EPGTFAVRVI ELCSSTMTCM KGTYLVHLTC TSSKTAREDL ESVVQKLFVP YTEMEIENEQ 
    VEKPRILWAL YFNMRDSSDI SRSCYNDLPS NVYVCSGPDC GLGNDNAVKQ AETLFQEICP 
    NEDFCPPPPN PEDIILDGDS LQPEASESSA IPEANSETFK ESTNLGNLEE SSE

Genular Protein ID: 3829388678

Symbol: B4DRL9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 505
  • Mass: 57265
  • Checksum: 15F801C543052012
  • Sequence:
  • MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE 
    QPKKNRITYS QIIKEGRRFN IDLVSKLLYS RGLLIDLLIK SNVSRYAEFK NITRILAFRE 
    GRVEQVPCSR ADVFNSKQLT MVEKRMLMKF LTFCMEYEKY PDEYKGYEEI TFYEYLKTQK 
    LTPNLQYIVM HSIAMTSETA SSTIDGLKAT KNFLHCLGRY GNTPFLFPLY GQGELPQCFC 
    RMCAVFGGIY CLRHSVQCLV VDKESRKCKA IIDQFGQRII SEHFLVEDSY FPENMCSRVQ 
    YRQISRAVLI TDRSVLKTDS DQQISILTVP AEEPGTFAVR VIELCSSTMT CMKGTYLVHL 
    TCTSSKTARE DLESVVQKLF VPYTEMEIEN EQVEKPRILW ALYFNMRDSS DISRSCYNDL 
    PSNVYVCSGP DCGLGNDNAV KQAETLFQEI CPNEDFCPPP PNPEDIILDG DSLQPEASES 
    SAIPEANSET FKESTNLGNL EESSE

Genular Protein ID: 2027369497

Symbol: A8K545_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 653
  • Mass: 73492
  • Checksum: ED59BECE7E32A271
  • Sequence:
  • MADTLPSEFD VIVIGTGLPE SIIAAACSRS GRRVLHVDSR SYYGGNWASF SFSGLLSWLK 
    EYQENSDIVS DSPVWQDQIL ENEEAIALCR KDKTIQHVEV FCYASQDLHE DVEEAGALQK 
    NHALVTSANS TEAADSAFLP TEDESLSTMS CEMLTEQTPS SDPENALEVN GAEVTGEKEN 
    HCDDKTCVPS TSAEDMSENV PIAEDTTEQP KKNRITYSQI IKEGRRFNID LVSKLLYSRG 
    LLIDLLIKSN VSRYAEFKNI TRILAFREGR VEQVPCSRAD VFNSKQLTMV EKRMLMKFLT 
    FCMEYEKYPD EYKGYEEITF YEYLKTQKLT PNLQYIVMHS IAMTSETASS TIDGLKATKN 
    FLHCLGRYGN TPFLFPLYGQ GELPQCFCRM CAVFGGIYCL RHSVQCLVVD KESRKCKAII 
    DQFGQRIISE HFLVEDSYFP ENMCSRVQYR QISRAVLITD RSVLKTDSDQ QISILTVPAE 
    EPGTFAVRVI ELCSSTMTCM KGTYLVHLTC TSSKTAREDL ESVVQKLFVP YTEMEIENEQ 
    VEKPRILWAL YFNMRDSSDI SRSCYNDLPS NVYVCSGPDC GLGNDNAVKQ AETLFQEICP 
    NEDFCPPPPN PEDIILDGDS LQPEASESSA IPEANSETFK ESTNLGNLEE SSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.