Details for: AKAP13
Associated with
Other Information
Genular Protein ID: 1452995007
Symbol: AKP13_HUMAN
Name: A-kinase anchor protein 13
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11696353
Title: Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling.
PubMed ID: 11696353
PubMed ID: 11546812
Title: AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation.
PubMed ID: 11546812
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9627117
Title: Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action.
PubMed ID: 9627117
PubMed ID: 9891067
Title: Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting.
PubMed ID: 9891067
PubMed ID: 8290273
Title: Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products.
PubMed ID: 8290273
PubMed ID: 1618839
Title: Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain.
PubMed ID: 1618839
PubMed ID: 11579095
Title: The proto-oncoprotein Brx activates estrogen receptor beta by a p38 mitogen-activated protein kinase pathway.
PubMed ID: 11579095
PubMed ID: 15249197
Title: Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2.
PubMed ID: 15249197
PubMed ID: 15229649
Title: Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex.
PubMed ID: 15229649
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16469733
Title: Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system.
PubMed ID: 16469733
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17537920
Title: The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy.
PubMed ID: 17537920
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21102438
Title: AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
PubMed ID: 21102438
DOI: 10.1038/ncb2130
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21224381
Title: A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation.
PubMed ID: 21224381
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23090968
Title: A-kinase-anchoring protein-Lbc anchors IkappaB kinase beta to support interleukin-6-mediated cardiomyocyte hypertrophy.
PubMed ID: 23090968
DOI: 10.1128/mcb.00887-12
PubMed ID: 23716597
Title: A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy.
PubMed ID: 23716597
DOI: 10.1128/mcb.00031-13
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 11285229
Title: A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.
PubMed ID: 11285229
PubMed ID: 25186459
Title: The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex.
PubMed ID: 25186459
DOI: 10.1042/bj20140606
PubMed ID: 24993829
Title: Structural insights into the activation of the RhoA GTPase by the lymphoid blast crisis (Lbc) oncoprotein.
PubMed ID: 24993829
Sequence Information:
- Length: 2813
- Mass: 307550
- Checksum: 6A8FDAC9A3D3B1F2
- Sequence:
MKLNPQQAPL YGDCVVTVLL AEEDKAEDDV VFYLVFLGST LRHCTSTRKV SSDTLETIAP GHDCCETVKV QLCASKEGLP VFVVAEEDFH FVQDEAYDAA QFLATSAGNQ QALNFTRFLD QSGPPSGDVN SLDKKLVLAF RHLKLPTEWN VLGTDQSLHD AGPRETLMHF AVRLGLLRLT WFLLQKPGGR GALSIHNQEG ATPVSLALER GYHKLHQLLT EENAGEPDSW SSLSYEIPYG DCSVRHHREL DIYTLTSESD SHHEHPFPGD GCTGPIFKLM NIQQQLMKTN LKQMDSLMPL MMTAQDPSSA PETDGQFLPC APEPTDPQRL SSSEETESTQ CCPGSPVAQT ESPCDLSSIV EEENTDRSCR KKNKGVERKG EEVEPAPIVD SGTVSDQDSC LQSLPDCGVK GTEGLSSCGN RNEETGTKSS GMPTDQESLS SGDAVLQRDL VMEPGTAQYS SGGELGGIST TNVSTPDTAG EMEHGLMNPD ATVWKNVLQG GESTKERFEN SNIGTAGASD VHVTSKPVDK ISVPNCAPAA SSLDGNKPAE SSLAFSNEET STEKTAETET SRSREESADA PVDQNSVVIP AAAKDKISDG LEPYTLLAAG IGEAMSPSDL ALLGLEEDVM PHQNSETNSS HAQSQKGKSS PICSTTGDDK LCADSACQQN TVTSSGDLVA KLCDNIVSES ESTTARQPSS QDPPDASHCE DPQAHTVTSD PVRDTQERAD FCPFKVVDNK GQRKDVKLDK PLTNMLEVVS HPHPVVPKME KELVPDQAVI SDSTFSLANS PGSESVTKDD ALSFVPSQKE KGTATPELHT ATDYRDGPDG NSNEPDTRPL EDRAVGLSTS STAAELQHGM GNTSLTGLGG EHEGPAPPAI PEALNIKGNT DSSLQSVGKA TLALDSVLTE EGKLLVVSES SAAQEQDKDK AVTCSSIKEN ALSSGTLQEE QRTPPPGQDT QQFHEKSISA DCAKDKALQL SNSPGASSAF LKAETEHNKE VAPQVSLLTQ GGAAQSLVPP GASLATESRQ EALGAEHNSS ALLPCLLPDG SDGSDALNCS QPSPLDVGVK NTQSQGKTSA CEVSGDVTVD VTGVNALQGM AEPRRENISH NTQDILIPNV LLSQEKNAVL GLPVALQDKA VTDPQGVGTP EMIPLDWEKG KLEGADHSCT MGDAEEAQID DEAHPVLLQP VAKELPTDME LSAHDDGAPA GVREVMRAPP SGRERSTPSL PCMVSAQDAP LPKGADLIEE AASRIVDAVI EQVKAAGALL TEGEACHMSL SSPELGPLTK GLESAFTEKV STFPPGESLP MGSTPEEATG SLAGCFAGRE EPEKIILPVQ GPEPAAEMPD VKAEDEVDFR ASSISEEVAV GSIAATLKMK QGPMTQAINR ENWCTIEPCP DAASLLASKQ SPECENFLDV GLGRECTSKQ GVLKRESGSD SDLFHSPSDD MDSIIFPKPE EEHLACDITG SSSSTDDTAS LDRHSSHGSD VSLSQILKPN RSRDRQSLDG FYSHGMGAEG RESESEPADP GDVEEEEMDS ITEVPANCSV LRSSMRSLSP FRRHSWGPGK NAASDAEMNH RSSMRVLGDV VRRPPIHRRS FSLEGLTGGA GVGNKPSSSL EVSSANAEEL RHPFSGEERV DSLVSLSEED LESDQREHRM FDQQICHRSK QQGFNYCTSA ISSPLTKSIS LMTISHPGLD NSRPFHSTFH NTSANLTESI TEENYNFLPH SPSKKDSEWK SGTKVSRTFS YIKNKMSSSK KSKEKEKEKD KIKEKEKDSK DKEKDKKTVN GHTFSSIPVV GPISCSQCMK PFTNKDAYTC ANCSAFVHKG CRESLASCAK VKMKQPKGSL QAHDTSSLPT VIMRNKPSQP KERPRSAVLL VDETATTPIF ANRRSQQSVS LSKSVSIQNI TGVGNDENMS NTWKFLSHST DSLNKISKVN ESTESLTDEG VGTDMNEGQL LGDFEIESKQ LEAESWSRII DSKFLKQQKK DVVKRQEVIY ELMQTEFHHV RTLKIMSGVY SQGMMADLLF EQQMVEKLFP CLDELISIHS QFFQRILERK KESLVDKSEK NFLIKRIGDV LVNQFSGENA ERLKKTYGKF CGQHNQSVNY FKDLYAKDKR FQAFVKKKMS SSVVRRLGIP ECILLVTQRI TKYPVLFQRI LQCTKDNEVE QEDLAQSLSL VKDVIGAVDS KVASYEKKVR LNEIYTKTDS KSIMRMKSGQ MFAKEDLKRK KLVRDGSVFL KNAAGRLKEV QAVLLTDILV FLQEKDQKYI FASLDQKSTV ISLKKLIVRE VAHEEKGLFL ISMGMTDPEM VEVHASSKEE RNSWIQIIQD TINTLNRDED EGIPSENEEE KKMLDTRARE LKEQLHQKDQ KILLLLEEKE MIFRDMAECS TPLPEDCSPT HSPRVLFRSN TEEALKGGPL MKSAINEVEI LQGLVSGNLG GTLGPTVSSP IEQDVVGPVS LPRRAETFGG FDSHQMNASK GGEKEEGDDG QDLRRTESDS GLKKGGNANL VFMLKRNSEQ VVQSVVHLYE LLSALQGVVL QQDSYIEDQK LVLSERALTR SLSRPSSLIE QEKQRSLEKQ RQDLANLQKQ QAQYLEEKRR REREWEARER ELREREALLA QREEEVQQGQ QDLEKEREEL QQKKGTYQYD LERLRAAQKQ LEREQEQLRR EAERLSQRQT ERDLCQVSHP HTKLMRIPSF FPSPEEPPSP SAPSIAKSGS LDSELSVSPK RNSISRTHKD KGPFHILSST SQTNKGPEGQ SQAPASTSAS TRLFGLTKPK EKKEKKKKNK TSRSQPGDGP ASEVSAEGEE IFC
Genular Protein ID: 3741129032
Symbol: B0AZU4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 385
- Mass: 42641
- Checksum: 001849D7DA7107C9
- Sequence:
MYERHKRRYS LCDISKVDRT VDVVLLKINR ENWCTIEPCP DAASLLASKQ SPECENFLDV GLGRECTSKQ GVLKRESGSD SDLFHSPSDD MDSIIFPKPE EEHLACDITG SSSSTDDTAS LDRHSSHGSD VSLSQILKPN RSRDRQSLDG FYSHGMGAEG RESESEPADP GDVEEEEMDS ITEVPANCSV LRSSMRSLSP FRRHSWGPGK NAASDAEMNH RSFSLEGLTG GAGVGNKPSS SLEVSSANAE ELRHPFSGEE RADSLVSLSE EDLESDQREH RMFDQQICHR SKQQGFNYCT SAISSPLTKS ISLMTISHPG LDNSRPFHST FHNTSANLTE SITEENYNFL PHSPSKKDSE WKSGTKVSRT FSYIKNKMSS SKKSK
Genular Protein ID: 3263593295
Symbol: A8MYJ1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
Sequence Information:
- Length: 1434
- Mass: 161841
- Checksum: E181F9F0421C7CC6
- Sequence:
MYERHKRRYS LCDISKVDRT VDVVLLKINR ENWCTIEPCP DAASLLASKQ SPECENFLDV GLGRECTSKQ GVLKRESGSD SDLFHSPSDD MDSIIFPKPE EEHLACDITG SSSSTDDTAS LDRHSSHGSD VSLSQILKPN RSRDRQSLDG FYSHGMGAEG RESESEPADP GDVEEEEMDS ITEVPANCSV LRSSMRSLSP FRRHSWGPGK NAASDAEMNH RSFSLEGLTG GAGVGNKPSS SLEVSSANAE ELRHPFSGEE RVDSLVSLSE EDLESDQREH RMFDQQICHR SKQQGFNYCT SAISSPLTKS ISLMTISHPG LDNSRPFHST FHNTSANLTE SITEENYNFL PHSPSKKDSE WKSGTKVSRT FSYIKNKMSS SKKSKEKEKE KDKIKEKEKD SKDKEKDKKT VNGHTFSSIP VVGPISCSQC MKPFTNKDAY TCANCSAFVH KGCRESLASC AKVKMKPKGS LQAHDTSSLP TVIMRNKPSQ PKERPRSAVL LVDETATTPI FANRRSQQSV SLSKSVSIQN ITGVGNDENM SNTWKFLSHS TDSLNKISKV NESTESLTDE GVGTDMNEGQ LLGDFEIESK QLEAESWSRI IDSKFLKQQK KDVVKRQEVI YELMQTEFHH VRTLKIMSGV YSQGMMADLL FEQQMVEKLF PCLDELISIH SQFFQRILER KKESLVDKSE KNFLIKRIGD VLVNQFSGEN AERLKKTYGK FCGQHNQSVN YFKDLYAKDK RFQAFVKKKM SSSVVRRLGI PECILLVTQR ITKYPVLFQR ILQCTKDNEV EQEDLAQSLS LVKDVIGAVD SKVASYEKKV RLNEIYTKTD SKSIMRMKSG QMFAKEDLKR KKLVRDGSVF LKNAAGRLKE VQAVLLTDIL VFLQEKDQKY IFASLDQKST VISLKKLIVR EVAHEEKGLF LISMGMTDPE MVEVHASSKE ERNSWIQIIQ DTINTLNRDE DEGIPSENEE EKKMLDTRAR ELKEQLHQKD QKILLLLEEK EMIFRDMAEC STPLPEDCSP THSPRVLFRS NTEEALKGGP LMKSAINEVE ILQGLVSGNL GGTLGPTVSS PIEQDVVGPV SLPRRAETFG GFDSHQMNAS KGGEKEEGDD GQDLRRTESD SGLKKGGNAN LVFMLKRNSE QVVQSVVHLY ELLSALQGVV LQQDSYIEDQ KLVLSERALT RSLSRPSSLI EQEKQRSLEK QRQDLANLQK QQAQYLEEKR RREREWEARE RELREREALL AQREEEVQQG QQDLEKEREE LQQKKGTYQY DLERLRAAQK QLEREQEQLR REAERLSQRQ TERDLCQVSH PHTKLMRIPS FFPSPEEPPS PSAPSIAKSG SLDSELSVSP KRNSISRTHK DKGPFHILSS TSQTNKGPEG QSQAPASTSA STRLFGLTKP KEKKEKKKKN KTSRSQPGDG PASEVSAEGE EIFC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.