Details for: TREX2

Gene ID: 11219

Symbol: TREX2

Ensembl ID: ENSG00000183479

Description: three prime repair exonuclease 2

Associated with

Other Information

Genular Protein ID: 967024650

Symbol: TREX2_HUMAN

Name: Three prime repair exonuclease 2

UniProtKB Accession Codes:

Q9BQ50 Q45F08 Q9UN77

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 5 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EC 2 EMBL 6 EPD 1 Ensembl 7 EvolutionaryTrace 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 neXtProt 1

Citations:

PubMed ID: 10391904

Title: Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.

PubMed ID: 10391904

DOI: 10.1074/jbc.274.28.19655

PubMed ID: 11278605

Title: Structure and expression of the TREX1 and TREX2 3'-->5' exonuclease genes.

PubMed ID: 11278605

DOI: 10.1074/jbc.m010051200

PubMed ID: 11279105

Title: Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins.

PubMed ID: 11279105

DOI: 10.1074/jbc.m100623200

PubMed ID: 15661738

Title: The human TREX2 3' ->5'-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis.

PubMed ID: 15661738

DOI: 10.1074/jbc.m500108200

Sequence Information:

  • Length: 236
  • Mass: 25922
  • Checksum: 3363BE40CFCC2300
  • Sequence:
    • MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAVHRSSL ENPEHDESGA LVLPRVLDKL 
TLCMCPERPF TAKASEITGL SSEGLARCRK AGFDGAVVRT LQAFLSRQAG PICLVAHNGF 
DYDFPLLCAE LRRLGARLPR DTVCLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF 
RAEPSAAHSA EGDVHTLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.