Details for: HPS5

Gene ID: 11234

Symbol: HPS5

Ensembl ID: ENSG00000110756

Description: HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

Associated with

Other Information

Genular Protein ID: 90164122

Symbol: HPS5_HUMAN

Name: Alpha-integrin-binding protein 63

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12548288

Title: Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6.

PubMed ID: 12548288

DOI: 10.1038/ng1087

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10094488

Title: Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains.

PubMed ID: 10094488

DOI: 10.1016/s0014-5793(99)00151-9

PubMed ID: 15030569

Title: Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6.

PubMed ID: 15030569

DOI: 10.1111/j.1600-0854.2004.0171.x

PubMed ID: 17301833

Title: Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5.

PubMed ID: 17301833

DOI: 10.1038/sj.jid.5700737

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25189619

Title: HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes.

PubMed ID: 25189619

DOI: 10.1242/jcs.141978

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15296495

Title: Cellular, molecular and clinical characterization of patients with Hermansky-Pudlak syndrome type 5.

PubMed ID: 15296495

DOI: 10.1111/j.1600-0854.2004.00208.x

Sequence Information:

  • Length: 1129
  • Mass: 127449
  • Checksum: C4FBF4EC90D1B8ED
  • Sequence:
  • MAFVPVIPES YSHVLAEFES LDPLLSALRL DSSRLKCTSI AVSRKWLALG SSGGGLHLIQ 
    KEGWKHRLFL SHREGAISQV ACCLHDDDYV AVATSQGLVV VWELNQERRG KPEQMYVSSE 
    HKGRRVTALC WDTAILRVFV GDHAGKVSAI KLNTSKQAKA AAAFVMFPVQ TITTVDSCVV 
    QLDYLDGRLL ISSLTRSFLC DTEREKFWKI GNKERDGEYG ACFFPGRCSG GQQPLIYCAR 
    PGSRMWEVNF DGEVISTHQF KKLLSLPPLP VITLRSEPQY DHTAGSSQSL SFPKLLHLSE 
    HCVLTWTERG IYIFIPQNVQ VLLWSEVKDI QDVAVCRNEL FCLHLNGKVS HLSLISVERC 
    VERLLRRGLW NLAARTCCLF QNSVIASRAR KTLTADKLEH LKSQLDHGTY NDLISQLEEL 
    ILKFEPLDSA CSSRRSSISS HESFSILDSG IYRIISSRRG SQSDEDSCSL HSQTLSEDER 
    FKEFTSQQEE DLPDQCCGSH GNEDNVSHAP VMFETDKNET FLPFGIPLPF RSPSPLVSLQ 
    AVKESVSSFV RKTTEKIGTL HTSPDLKVRP ELRGDEQSCE EDVSSDTCPK EEDTEEEKEV 
    TSPPPEEDRF QELKVATAEA MTKLQDPLVL FESESLRMVL QEWLSHLEKT FAMKDFSGVS 
    DTDNSSMKLN QDVLLVNESK KGILDEDNEK EKRDSLGNEE SVDKTACECV RSPRESLDDL 
    FQICSPCAIA SGLRNDLAEL TTLCLELNVL NSKIKSTSGH VDHTLQQYSP EILACQFLKK 
    YFFLLNLKRA KESIKLSYSN SPSVWDTFIE GLKEMASSNP VYMEMEKGDL PTRLKLLDDE 
    VPFDSPLLVV YATRLYEKFG ESALRSLIKF FPSILPSDII QLCHHHPAEF LAYLDSLVKS 
    RPEDQRSSFL ESLLQPESLR LDWLLLAVSL DAPPSTSTMD DEGYPRPHSH LLSWGYSQLI 
    LHLIKLPADF ITKEKMTDIC RSCGFWPGYL ILCLELERRR EAFTNIVYLN DMSLMEGDNG 
    WIPETVEEWK LLLHLIQSKS TRPAPQESLN GSLSDGPSPI NVENVALLLA KAMGPDRAWS 
    LLQECGLALE LSEKFTRTCD ILRIAEKRQR ALIQSMLEKC DRFLWSQQA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.