ZHX1 | ENSG00000165156 | NCBI 11244

Details for: ZHX1

Gene ID: 11244

Symbol: ZHX1

Ensembl ID: ENSG00000165156

Description: zinc fingers and homeoboxes 1

Associated with

Cell differentiation
(GO:0030154)
Chromatin
(GO:0000785)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Metal ion binding
(GO:0046872)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Regulation of transcription by rna polymerase ii
(GO:0006357)

Other Information

Proteins

Zinc fingers and homeoboxes protein 1

Genular Protein ID: 1426201984

Symbol: ZHX1_HUMAN

Name: Zinc fingers and homeoboxes protein 1

UniProtKB Accession Codes:

Q9UKY1 Q8IWD8

Database IDs:

Citations:

PubMed ID: 10441475

Title: Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y.

PubMed ID: 10441475

DOI: 10.1006/bbrc.1999.1087

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10571058

Title: Identification of proteins that interact with NF-YA.

PubMed ID: 10571058

DOI: 10.1016/s0014-5793(99)01311-3

PubMed ID: 12237128

Title: Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1).

PubMed ID: 12237128

DOI: 10.1016/s0006-291x(02)02203-9

PubMed ID: 12659632

Title: Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.

PubMed ID: 12659632

DOI: 10.1042/bj20021866

PubMed ID: 12741956

Title: Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.

PubMed ID: 12741956

DOI: 10.1042/bj20030171

PubMed ID: 17056598

Title: ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.

PubMed ID: 17056598

DOI: 10.1074/jbc.m606664200

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17303076

Title: Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression.

PubMed ID: 17303076

DOI: 10.1016/j.bbrc.2007.01.187

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 19348505

Title: The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension.

PubMed ID: 19348505

DOI: 10.1021/bi9001997

PubMed ID: 20509910

Title: Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.

PubMed ID: 20509910

DOI: 10.1186/1472-6807-10-13

Sequence Information:

Length: 873
Mass: 98098
Checksum: 66CF1CEC5EF824E5
Sequence:

MASRRKSTTP CMVLASEQDP DLELISDLDE GPPVLTPVEN TRAESISSDE EVHESVDSDN 
QQNKKVEGGY ECKYCTFQTP DLNMFTFHVD SEHPNVVLNS SYVCVECNFL TKRYDALSEH 
NLKYHPGEEN FKLTMVKRNN QTIFEQTIND LTFDGSFVKE ENAEQAESTE VSSSGISISK 
TPIMKMMKNK VENKRIAVHH NSVEDVPEEK ENEIKPDREE IVENPSSSAS ESNTSTSIVN 
RIHPSTASTV VTPAAVLPGL AQVITAVSAQ QNSNLIPKVL IPVNSIPTYN AALDNNPLLL 
NTYNKFPYPT MSEITVLSAQ AKYTEEQIKI WFSAQRLKHG VSWTPEEVEE ARRKQFNGTV 
HTVPQTITVI PTHISTGSNG LPSILQTCQI VGQPGLVLTQ VAGTNTLPVT APIALTVAGV 
PSQNNIQKSQ VPAAQPTAET KPATAAVPTS QSVKHETALV NPDSFGIRAK KTKEQLAELK 
VSYLKNQFPH DSEIIRLMKI TGLTKGEIKK WFSDTRYNQR NSKSNQCLHL NNDSSTTIII 
DSSDETTESP TVGTAQPKQS WNPFPDFTPQ KFKEKTAEQL RVLQASFLNS SVLTDEELNR 
LRAQTKLTRR EIDAWFTEKK KSKALKEEKM EIDESNAGSS KEEAGETSPA DESGAPKSGS 
TGKICKKTPE QLHMLKSAFV RTQWPSPEEY DKLAKESGLA RTDIVSWFGD TRYAWKNGNL 
KWYYYYQSAN SSSMNGLSSL RKRGRGRPKG RGRGRPRGRP RGSKRINNWD RGPSLIKFKT 
GTAILKDYYL KHKFLNEQDL DELVNKSHMG YEQVREWFAE RQRRSELGIE LFEENEEEDE 
VIDDQEEDEE ETDDSDTWEP PRHVKRKLSK SDD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ZHX1

Associated with

Other Information

Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y. PubMed ID: 10441475

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of proteins that interact with NF-YA. PubMed ID: 10571058

Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1). PubMed ID: 12237128

Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3. PubMed ID: 12659632

Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. PubMed ID: 12741956

ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. PubMed ID: 17056598

A probability-based approach for high-throughput protein phosphorylation analysis and site localization. PubMed ID: 16964243

Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression. PubMed ID: 17303076

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Uncovering global SUMOylation signaling networks in a site-specific manner. PubMed ID: 25218447

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension. PubMed ID: 19348505

Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains. PubMed ID: 20509910