Details for: PACSIN2

Gene ID: 11252

Symbol: PACSIN2

Ensembl ID: ENSG00000100266

Description: protein kinase C and casein kinase substrate in neurons 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 2.8
    Marker Score: 11,673
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 2.72
    Marker Score: 10,538
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.64
    Marker Score: 1,429
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.39
    Marker Score: 2,278
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.17
    Marker Score: 4,762
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.01
    Marker Score: 32,291
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.86
    Marker Score: 3,926
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.82
    Marker Score: 2,094
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.81
    Marker Score: 27,080
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.76
    Marker Score: 1,947
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.72
    Marker Score: 855
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.7
    Marker Score: 491
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.68
    Marker Score: 17,307
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.67
    Marker Score: 1,176
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.66
    Marker Score: 1,794
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.65
    Marker Score: 62,581
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.64
    Marker Score: 529
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.64
    Marker Score: 29,035
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.63
    Marker Score: 3,846
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.56
    Marker Score: 932
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.55
    Marker Score: 10,126
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.54
    Marker Score: 1,924
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.53
    Marker Score: 4,800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.51
    Marker Score: 474
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 1.5
    Marker Score: 1,484
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.49
    Marker Score: 1,286
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.47
    Marker Score: 1,131
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.45
    Marker Score: 1,283
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.42
    Marker Score: 537
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.42
    Marker Score: 2,066
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.41
    Marker Score: 819
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.38
    Marker Score: 50,726
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.36
    Marker Score: 2,624
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.36
    Marker Score: 30,313
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.36
    Marker Score: 714
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.35
    Marker Score: 2,386
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.32
    Marker Score: 919
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3
    Marker Score: 20,337
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.28
    Marker Score: 1,453
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.28
    Marker Score: 5,311
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.28
    Marker Score: 1,807
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.26
    Marker Score: 5,125
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.26
    Marker Score: 1,577
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.24
    Marker Score: 10,684
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.23
    Marker Score: 1,440
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.23
    Marker Score: 3,508
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.23
    Marker Score: 4,359
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.22
    Marker Score: 75,046
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.22
    Marker Score: 26,005
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.21
    Marker Score: 703
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.2
    Marker Score: 5,005
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.2
    Marker Score: 1,196
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.18
    Marker Score: 23,540
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.17
    Marker Score: 8,991
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.17
    Marker Score: 2,668
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.17
    Marker Score: 423
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.16
    Marker Score: 1,864
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.15
    Marker Score: 10,842
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 1.15
    Marker Score: 1,384
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.14
    Marker Score: 1,763
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.14
    Marker Score: 4,401
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.14
    Marker Score: 4,402
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.13
    Marker Score: 772
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.13
    Marker Score: 423
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.13
    Marker Score: 3,878
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.13
    Marker Score: 925
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.13
    Marker Score: 10,690
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.12
    Marker Score: 1,167
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.12
    Marker Score: 1,138
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.12
    Marker Score: 4,694
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.11
    Marker Score: 1,344
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.1
    Marker Score: 2,072
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.09
    Marker Score: 4,034
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.08
    Marker Score: 724
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.08
    Marker Score: 604
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.07
    Marker Score: 1,140
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.07
    Marker Score: 1,072
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.07
    Marker Score: 985
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 1.04
    Marker Score: 648
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.03
    Marker Score: 1,485
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.02
    Marker Score: 299
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.02
    Marker Score: 1,616
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 1.02
    Marker Score: 264
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.01
    Marker Score: 5,334
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.01
    Marker Score: 258
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.01
    Marker Score: 6,516
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.01
    Marker Score: 290
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.01
    Marker Score: 1,298
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1
    Marker Score: 6,383
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1
    Marker Score: 1,048
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,619
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.99
    Marker Score: 483
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,846
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.99
    Marker Score: 2,331
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.99
    Marker Score: 366
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.99
    Marker Score: 289
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.98
    Marker Score: 282
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.98
    Marker Score: 397
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,374
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.97
    Marker Score: 568

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PACSIN2 is a cytoskeletal protein that interacts with various signaling molecules, including protein kinase C (PKC) and casein kinase (CK). Its unique structure, comprising three ankyrin repeats and a C-terminal domain, enables it to bind to multiple proteins, modulating their activity and localization. PACSIN2 is also involved in the regulation of endocytosis, a process critical for maintaining cellular homeostasis and synaptic plasticity. Its expression is tightly regulated, with significant changes observed in response to neuronal activity, stress, and disease. **Pathways and Functions:** PACSIN2 is involved in several key cellular pathways, including: 1. **Actin Cytoskeleton Organization:** PACSIN2 interacts with actin-binding proteins, modulating the organization and dynamics of the actin cytoskeleton. 2. **Endocytosis:** PACSIN2 regulates the endocytic pathway, influencing the uptake of molecules and proteins into the cell. 3. **Synaptic Transmission:** PACSIN2 is involved in the regulation of glutamatergic synaptic transmission, a critical process for neuronal communication. 4. **Caveolin-mediated Endocytosis:** PACSIN2 interacts with caveolin, a protein that regulates the formation of caveolae, small invaginations of the plasma membrane. **Clinical Significance:** Dysregulation of PACSIN2 has been implicated in various diseases, including: 1. **Neurological Disorders:** PACSIN2 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Cancer:** PACSIN2 has been identified as a potential oncogene, with its expression elevated in various types of cancer, including breast, lung, and colon cancer. 3. **Neuropathic Pain:** PACSIN2 has been implicated in the regulation of neuropathic pain, a chronic condition characterized by pain in the absence of injury. In conclusion, PACSIN2 is a multifunctional protein that plays a critical role in maintaining cellular homeostasis and regulating various cellular processes. Its dysregulation has been implicated in various diseases, highlighting the importance of PACSIN2 in understanding the pathogenesis of neurological and non-neurological disorders. Further research is needed to elucidate the mechanisms by which PACSIN2 regulates cellular processes and to identify potential therapeutic targets for the treatment of these diseases.

Genular Protein ID: 1131871953

Symbol: PACN2_HUMAN

Name: Protein kinase C and casein kinase substrate in neurons protein 2

UniProtKB Accession Codes:

Q9UNF0 O95921 Q96HV9 Q9H0D3 Q9NPN1 Q9Y4V2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTAC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 4 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10431838

Title: PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins.

PubMed ID: 10431838

DOI: 10.1016/s0014-5793(99)00830-3

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11082044

Title: All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

PubMed ID: 11082044

DOI: 10.1242/jcs.113.24.4511

PubMed ID: 11179684

Title: PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.

PubMed ID: 11179684

DOI: 10.1016/s0378-1119(00)00531-x

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21693584

Title: The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration.

PubMed ID: 21693584

DOI: 10.1242/jcs.080630

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23129763

Title: The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization.

PubMed ID: 23129763

DOI: 10.1074/jbc.m112.391078

PubMed ID: 23236520

Title: Versatile membrane deformation potential of activated pacsin.

PubMed ID: 23236520

DOI: 10.1371/journal.pone.0051628

PubMed ID: 22323287

Title: EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.

PubMed ID: 22323287

DOI: 10.1091/mbc.e11-09-0787

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23596323

Title: Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.

PubMed ID: 23596323

DOI: 10.1091/mbc.e13-01-0026

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29891700

Title: HIV-1 gag recruits PACSIN2 to promote virus spreading.

PubMed ID: 29891700

DOI: 10.1073/pnas.1801849115

PubMed ID: 31242077

Title: RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread.

PubMed ID: 31242077

DOI: 10.1091/mbc.e19-04-0197

PubMed ID: 31801866

Title: PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.

PubMed ID: 31801866

DOI: 10.1128/jvi.01531-19

PubMed ID: 19549836

Title: Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.

PubMed ID: 19549836

DOI: 10.1073/pnas.0902974106

PubMed ID: 20188097

Title: Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II.

PubMed ID: 20188097

DOI: 10.1016/j.febslet.2010.02.058

PubMed ID: 22573331

Title: Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules.

PubMed ID: 22573331

DOI: 10.1074/jbc.m112.358960

Sequence Information:

  • Length: 486
  • Mass: 55739
  • Checksum: 821DBEF65DAD1AA8
  • Sequence:
    • MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 
EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF 
HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK EVEAAKKAHH AACKEEKLAI SREANSKADP 
SLNPEQLKKL QDKIEKCKQD VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR 
LRFFREVLLE VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ 
FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSTLNVPSN PAQSAQSQSS 
YNPFEDEDDT GSTVSEKDDT KAKNVSSYEK TQSYPTDWSD DESNNPFSST DANGDSNPFD 
DDATSGTEVR VRALYDYEGQ EHDELSFKAG DELTKMEDED EQGWCKGRLD NGQVGLYPAN 
YVEAIQ

Genular Protein ID: 2330780069

Symbol: Q6FIA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6FIA3

Database IDs:

ARBA 20 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ExpressionAtlas 1 GO 9 Gene3D 2 Genevisible 1 GenomeRNAi 1 HOGENOM 1 IntAct 1 InterPro 7 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Sequence Information:

  • Length: 445
  • Mass: 51353
  • Checksum: 1DA87A2D42B5D5F9
  • Sequence:
    • MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 
EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF 
HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK EVEAAKKAHH AACKEEKLAI SREANSKADP 
SLNPEQLKKL QDKIEKCKQD VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR 
LRFFREVLLE VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ 
FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSVSSYEKT QSYPTDWSDD 
ESNNPFSSTD ANGDSNPFDD DATSGTEVRV RALYDYEGQE HDELSFKAGD ELTKMEDEDE 
QGWCKGRLDN GQVGLYPANY VEAIQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.