Details for: PACSIN2

Gene ID: 11252

Symbol: PACSIN2

Ensembl ID: ENSG00000100266

Description: protein kinase C and casein kinase substrate in neurons 2

Associated with

Other Information

Genular Protein ID: 1131871953

Symbol: PACN2_HUMAN

Name: Protein kinase C and casein kinase substrate in neurons protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10431838

Title: PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins.

PubMed ID: 10431838

DOI: 10.1016/s0014-5793(99)00830-3

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11082044

Title: All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.

PubMed ID: 11082044

DOI: 10.1242/jcs.113.24.4511

PubMed ID: 11179684

Title: PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.

PubMed ID: 11179684

DOI: 10.1016/s0378-1119(00)00531-x

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21693584

Title: The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration.

PubMed ID: 21693584

DOI: 10.1242/jcs.080630

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23129763

Title: The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization.

PubMed ID: 23129763

DOI: 10.1074/jbc.m112.391078

PubMed ID: 23236520

Title: Versatile membrane deformation potential of activated pacsin.

PubMed ID: 23236520

DOI: 10.1371/journal.pone.0051628

PubMed ID: 22323287

Title: EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.

PubMed ID: 22323287

DOI: 10.1091/mbc.e11-09-0787

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23596323

Title: Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.

PubMed ID: 23596323

DOI: 10.1091/mbc.e13-01-0026

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29891700

Title: HIV-1 gag recruits PACSIN2 to promote virus spreading.

PubMed ID: 29891700

DOI: 10.1073/pnas.1801849115

PubMed ID: 31242077

Title: RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread.

PubMed ID: 31242077

DOI: 10.1091/mbc.e19-04-0197

PubMed ID: 31801866

Title: PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.

PubMed ID: 31801866

DOI: 10.1128/jvi.01531-19

PubMed ID: 19549836

Title: Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.

PubMed ID: 19549836

DOI: 10.1073/pnas.0902974106

PubMed ID: 20188097

Title: Mapping of the basic amino-acid residues responsible for tubulation and cellular protrusion by the EFC/F-BAR domain of pacsin2/Syndapin II.

PubMed ID: 20188097

DOI: 10.1016/j.febslet.2010.02.058

PubMed ID: 22573331

Title: Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules.

PubMed ID: 22573331

DOI: 10.1074/jbc.m112.358960

Sequence Information:

  • Length: 486
  • Mass: 55739
  • Checksum: 821DBEF65DAD1AA8
  • Sequence:
  • MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 
    EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF 
    HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK EVEAAKKAHH AACKEEKLAI SREANSKADP 
    SLNPEQLKKL QDKIEKCKQD VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR 
    LRFFREVLLE VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ 
    FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSTLNVPSN PAQSAQSQSS 
    YNPFEDEDDT GSTVSEKDDT KAKNVSSYEK TQSYPTDWSD DESNNPFSST DANGDSNPFD 
    DDATSGTEVR VRALYDYEGQ EHDELSFKAG DELTKMEDED EQGWCKGRLD NGQVGLYPAN 
    YVEAIQ

Genular Protein ID: 2330780069

Symbol: Q6FIA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 445
  • Mass: 51353
  • Checksum: 1DA87A2D42B5D5F9
  • Sequence:
  • MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 
    EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV KASLMNDDFE KIKNWQKEAF 
    HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK EVEAAKKAHH AACKEEKLAI SREANSKADP 
    SLNPEQLKKL QDKIEKCKQD VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR 
    LRFFREVLLE VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ 
    FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSVSSYEKT QSYPTDWSDD 
    ESNNPFSSTD ANGDSNPFDD DATSGTEVRV RALYDYEGQE HDELSFKAGD ELTKMEDEDE 
    QGWCKGRLDN GQVGLYPANY VEAIQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.