HRH3 | ENSG00000101180 | NCBI 11255

Details for: HRH3

Gene ID: 11255

Symbol: HRH3

Ensembl ID: ENSG00000101180

Description: histamine receptor H3

Associated with

Amine ligand-binding receptors
(R-HSA-375280)
Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
Gpcr ligand binding
(R-HSA-500792)
Histamine receptors
(R-HSA-390650)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Adenylate cyclase-inhibiting g protein-coupled acetylcholine receptor signaling pathway
(GO:0007197)
Chemical synaptic transmission
(GO:0007268)
Cognition
(GO:0050890)
Dendrite
(GO:0030425)
G protein-coupled acetylcholine receptor activity
(GO:0016907)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
G protein-coupled serotonin receptor signaling pathway
(GO:0098664)
Histamine receptor activity
(GO:0004969)
Negative regulation of glutamate secretion
(GO:0014050)
Negative regulation of serotonin secretion
(GO:0014063)
Neurotransmitter secretion
(GO:0007269)
Plasma membrane
(GO:0005886)
Presynapse
(GO:0098793)
Regulation of norepinephrine secretion
(GO:0014061)
Synapse
(GO:0045202)

Other Information

Proteins

Histamine H3 receptor

Genular Protein ID: 3349913982

Symbol: HRH3_HUMAN

Name: Histamine H3 receptor

UniProtKB Accession Codes:

Q9Y5N1 Q4QRI7 Q9GZX2 Q9H4K8

Database IDs:

Citations:

PubMed ID: 10347254

Title: Cloning and functional expression of the human histamine H3 receptor.

PubMed ID: 10347254

DOI: 10.1124/mol.55.6.1101

PubMed ID: 11118334

Title: Molecular cloning and characterization of a new human histamine receptor, HH4R.

PubMed ID: 11118334

DOI: 10.1006/bbrc.2000.4008

PubMed ID: 11284713

Title: Genomic organization and characterization of splice variants of the human histamine H3 receptor.

PubMed ID: 11284713

DOI: 10.1042/0264-6021:3550279

PubMed ID: 11956964

Title: Structure of the human histamine H3 receptor gene (HRH3) and identification of naturally occurring variations.

PubMed ID: 11956964

DOI: 10.1007/s007020200036

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 445
Mass: 48671
Checksum: 2ACF7440FBE95B6C
Sequence:

MERAPPDGPL NASGALAGEA AAAGGARGFS AAWTAVLAAL MALLIVATVL GNALVMLAFV 
ADSSLRTQNN FFLLNLAISD FLVGAFCIPL YVPYVLTGRW TFGRGLCKLW LVVDYLLCTS 
SAFNIVLISY DRFLSVTRAV SYRAQQGDTR RAVRKMLLVW VLAFLLYGPA ILSWEYLSGG 
SSIPEGHCYA EFFYNWYFLI TASTLEFFTP FLSVTFFNLS IYLNIQRRTR LRLDGAREAA 
GPEPPPEAQP SPPPPPGCWG CWQKGHGEAM PLHRYGVGEA AVGAEAGEAT LGGGGGGGSV 
ASPTSSSGSS SRGTERPRSL KRGSKPSASS ASLEKRMKMV SQSFTQRFRL SRDRKVAKSL 
AVIVSIFGLC WAPYTLLMII RAACHGHCVP DYWYETSFWL LWANSAVNPV LYPLCHHSFR 
RAFTKLLCPQ KLKIQPHSSL EHCWK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: HRH3

Associated with

Other Information

Cloning and functional expression of the human histamine H3 receptor. PubMed ID: 10347254

Molecular cloning and characterization of a new human histamine receptor, HH4R. PubMed ID: 11118334

Genomic organization and characterization of splice variants of the human histamine H3 receptor. PubMed ID: 11284713

Structure of the human histamine H3 receptor gene (HRH3) and identification of naturally occurring variations. PubMed ID: 11956964

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052